Biotech-Products Laboratory

Biotech-Products Laboratory BIOTECH-PRODUCTS LABORATORY provides services in research collaboration, consultation and academic-i

04/07/2023

HealthLatest Top Article Revolutionising health with postbiotics By author - July 3, 2023 0 66 Share on Facebook Tweet on Twitter Dr Tan Joo Shun with the postbiotic product of Biotenova BY JOTISRI VASUDEVAN IN THE ever-evolving field of biotechnology, the emergence of postbiotics as a groundbreakin...

12/08/2021

Class II biosafety cabinet is defined as a ventilated cabinet for personnel, product and environmental protection for microbiological work or sterile pharmacy compounding.

It has been used by our research team to study the multi- and pan-resistant bacteria (also known as “superbugs”) which cause infections that are not treatable with existing antimicrobial medicines such as antibiotics. Interesting and challenging research.

12/08/2021

Incubator shaker is used for mixing, incubation and cultivation of biological liquid. Testing the new incubator shaker in our laboratory.

Purification of protein using a column chromatography. Column chromatography consists of a stationary solid phase that a...
03/07/2021

Purification of protein using a column chromatography. Column chromatography consists of a stationary solid phase that adsorbs and separates the compounds passing through it with the help of a liquid mobile phase.

A strict fermentation process is needed to produce the microbes or microbial metabolites like probiotics, enzymes, bacte...
20/06/2021

A strict fermentation process is needed to produce the microbes or microbial metabolites like probiotics, enzymes, bacteriocin and etc. Culture medium, temperature, pH, agitation speed, inoculum size, fermentation time, pressure, sterilisation, clean in place (CIP) and etc are the things to take into consideration. This is called 'Fermentation Technology'. Using the automated 150L bioreactor and 750L bioreactor, we can produce our desired microbial products via fermentation. So, do you know how to produce a yogurt drink?

Enterococcus faecium. E. faecium has long been recognised for its probiotic benefits and is widely used around the world...
20/06/2021

Enterococcus faecium. E. faecium has long been recognised for its probiotic benefits and is widely used around the world. One of the major benefits of E. faecium is that it is uniquely suited to survive the digestive process and flourish in the gut. It promotes a balanced gut environment by competing for resources that harmful organisms would otherwise consume and use to grow. It also competes with harmful organisms for adhesion sites – areas on the surface of cells to which other cells and molecules can bind. Hence, this ‘multitasking’ strain is commonly found in human probiotic supplements.

20/06/2021

A simple glass airlift bioreactor - the internal circulation and mixing are achieved by bubbling air. It is used to cultivate shear-sensitive aerobic microorganism.

A prototype of aqueous impregnated resins system (AIRS) for purifying antimicrobial peptide - bacteriocin from probiotic...
20/06/2021

A prototype of aqueous impregnated resins system (AIRS) for purifying antimicrobial peptide - bacteriocin from probiotics. Well done to my research team.

Chitin extraction from shrimp wastes by single step fermentation with Lactobacillus acidophilus. The astaxanthin (carote...
04/12/2020

Chitin extraction from shrimp wastes by single step fermentation with Lactobacillus acidophilus. The astaxanthin (carotenoids) and lactic acid co-produced in the hydrolysate are useful in many applications.

DOI: 10.1111/jfpp.14895

Extraction of C-phycocyanin from cyanobacteria, Phormidium tergestinum using aqueous two phase system. Amazing color-cha...
04/12/2020

Extraction of C-phycocyanin from cyanobacteria, Phormidium tergestinum using aqueous two phase system. Amazing color-changing before and after purification. The yellowish color of crude extract turns into light blue color C-phycocyanin.

DOI: 10.1080/10826068.2020.1808793

You may think freeze-drying or spray drying of probiotic, Lactobacillus acidophilus is a simple process. Indeed, we thou...
04/12/2020

You may think freeze-drying or spray drying of probiotic, Lactobacillus acidophilus is a simple process. Indeed, we thought that too. Finally, the cells survive after many formulation trials.

DOI:10.1080/09168451.2020.1770572

Our Lactobacillus ferment filtrate is produced by Lactobacillus bulgaricus, which is a probiotic ingredient with antimic...
04/12/2020

Our Lactobacillus ferment filtrate is produced by Lactobacillus bulgaricus, which is a probiotic ingredient with antimicrobial activity, soothing and maybe anti-aging properties due to its content of bacteriocin, lactic acid, hyaluronic acid and etc. Production of L. bulgaricus in skimmed milk makes the ferment filtrate scented.

DOI: 10.3390/molecules25225332

Green fungus - Trichoderma genus interacts with plants by inducing their defense system and promoting plant growth. Isol...
04/12/2020

Green fungus - Trichoderma genus interacts with plants by inducing their defense system and promoting plant growth. Isolation and growing the beautiful fungus make us know more on the world of tiny microorganism.

Bioethanol and animal feed production from palm kernel cake is a challenging work. Simultaneous saccharification and yea...
04/12/2020

Bioethanol and animal feed production from palm kernel cake is a challenging work. Simultaneous saccharification and yeast solid-state fermentation are conducted to produce high yield of bioethanol and total protein content.

What is bacteriocin? Bacteriocins are ribosomally synthesized antimicrobial peptides produced by various bacteria, inclu...
04/12/2020

What is bacteriocin?
Bacteriocins are ribosomally synthesized antimicrobial peptides produced by various bacteria, including food-grade lactic acid bacteria.
Morphology of Listeria monocytogenes ATCC 7644 was observed under transmission electron microscope. Figure A represents L. monocytogenes without the treatment of bacteriocin. Figure B represents L. monocytogenes with treatment of bacteriocin derived from Lactobacillus brevis C23, in which the L. monocytogenes cell wall was disrupted. It shows the potential of this antimicrobial peptide to be used as bio-preservative in food industry.

Fermentation is an Art of Science. Production of several beneficial microorganisms in 2-L bioreactor and scaled-up to 15...
04/12/2020

Fermentation is an Art of Science. Production of several beneficial microorganisms in 2-L bioreactor and scaled-up to 15-L bioreactor needs passion and patience. Symbiosis of lactic acid bacteria, Bacillus and yeast serves as a good probiotic solution.

Enzymatic hydrolysis of soybean pulp improves the functionalities while yeast fermentation enhances the total protein co...
04/12/2020

Enzymatic hydrolysis of soybean pulp improves the functionalities while yeast fermentation enhances the total protein content. Good medium formulation and bioprocess strategy are needed to make the process of making value-added food ingredient, bio-okara successful. Well done!

Lactobacillus acidophilus fermented okara with treatment of carbohydrase hydrolysis in a 2L shake flask. Metabolomic ana...
04/12/2020

Lactobacillus acidophilus fermented okara with treatment of carbohydrase hydrolysis in a 2L shake flask. Metabolomic analysis will be conducted to understand better on the fermentation mechanism.

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