27/01/2022
No 8
MALARIA
Definition; This is a mosquito-borne infectious disease that affects human and other animals.
Malaria causes symtoms that typically includes; fever, tiredness, vomiting and headache. In severe cases it can cause yellow skin, seizures, coma or death.
Symtoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have references of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symtoms. The partial resistance disappears over months to years if the person has no continuing exposure to mosquito bites.
Malaria is caused by single- celled microorganisms of plasmodium groups, it's spread exclusively through bites of infected Anopheles mosquitoes. The mosquito bite introduces the parasites from the mosquito' s saliva into a person's blood. The parasites travel to the liver where they mature and reproduce.
Five species of plasmodium can infect and spread by humans.
Most deaths are caused by P. falciparium, whereas P. vivax, P. ovale and P. malariae generally cause a milder form of malaria. The species P. knowlesi rarely cause disease in humans.
PREVENTION
Mosquito nets, insects repellent, mosquito control and medications.
TREATMENT:
Malaria is treated with antimalarial medications, the ones used depends on the type and severity if the disease. While medications against fever are commonly used, their effects on outcomes are not clear. Providing free antimalarial drugs to households may reduce childhood deaths when used appropriately.
Uncomplicated Malaria and severe/complicated malaria;
Simple or uncomplicated malaria may be treated with oral medications while severe /complicated can be treated with intravenous use of antimalarials.
Artemisinin in combination with other antimalarials (known as Artemisinin combination therapy or ACT) is about 90% effective when used to treat uncomplicated malaria.
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Pharm J C Obioha 27/1/2022