13/11/2025
UNDERSTANDING RHESUS (Rh) COMPATIBILITY IN PREGNANCY.
Did you know your blood type can affect your baby's health during pregnancy? Let's talk about something called Rhesus (Rh) compatibility - an important topic every expectant mother should know.
What is Rh factor?
The Rhesus (Rh) factor is a protein found on the surface of red blood cells.
If you have the protein → you are Rh positive (Rh+).
If you don't → you are Rh negative (Rh–).
N.B: This doesn't usually cause any problem – unless an Rh– mother is carrying an Rh+ baby.
Why It Matters:
During pregnancy or delivery, a small amount of the baby's blood can mix with the mother's.
If the mother is Rh– and the baby is Rh+, her immune system may see the baby's blood as "foreign" and make antibodies to fight it.
This is called Rh incompatibility.
Without treatment, these antibodies can cross the placenta in future pregnancies and destroy the next baby's red blood cells, leading to hemolytic disease of the newborn (HDN) – a serious condition.
There's an injection called Anti-D immunoglobulin (Rho(D) immune globulin).
It works like a shield to stop your body from making those harmful antibodies.
When is it given?
✅Around 28 weeks of pregnancy
✅Within 72 hours after delivery (if your baby is confirmed Rh+)
✅It may also be given after events like miscarriage, bleeding, or certain procedures (e.g., amniocentesis).
Knowing your Rh status early in pregnancy and getting the Anti-D injection on time can protect your current and future babies.
Always check with your healthcare provider – they'll guide you through the right timing and dosage.
© Christie 🌹