25/10/2022
What causes female infertility?
There are many possible causes of infertility. However, it can be difficult to pinpoint the exact cause, and some couples have “unexplained” infertility or “multifactorial” infertility (multiple causes, often both male and female factors). Some possible causes of female factor infertility can include:
Problems with the uterus: This includes polyps, fibroids, septum or adhesions inside the cavity of the uterus. Polyps and fibroids can form on their own at any time, whereas other abnormalities (like a septum) are present at birth. Adhesions can form after a surgery like a dilation and curettage (D&C).
Problems with the fallopian tubes: The most common cause of “tubal factor” infertility is pelvic inflammatory disease, usually caused by chlamydia and gonorrhea.
Problems with ovulation: There are many reasons why a woman may not ovulate (release an egg) regularly. Hormonal imbalances, a past eating disorder, substance abuse, thyroid conditions, severe stress and pituitary tumors are all examples of things that can affect ovulation.
Problems with egg number and quality: Women are born with all the eggs they will ever have, and this supply can “run out” early before menopause. In addition, some eggs will have the wrong number of chromosomes and cannot fertilize or grow into a healthy fetus. Some of these chromosomal issues (such as “balanced translocation”) may affect all of the eggs. Others are random but become more common as a woman gets older.
Who is at risk for female infertility?
Many factors can increase a woman’s risk of female infertility. General health conditions, genetic (inherited) traits, lifestyle choices and age can all contribute to female infertility. Specific factors can include:
Age.
Hormone issue that prevents ovulation.
Abnormal menstrual cycle.
Obesity.
Being underweight.
Having a low body-fat content from extreme exercise.
Endometriosis.
Structural problems (problems with the fallopian tubes, uterus or ovaries).
Uterine fibroids.
Cysts.
Tumors.
Autoimmune disorders (lupus, rheumatoid arthritis, Hashimoto’s disease, thyroid gland conditions).
S*xually transmitted infections (STIs).
Polycystic O***y Syndrome (PCOS).
Primary O***y Insufficiency (POI).
Excessive substance use (heavy drinking).
Smoking.
DES syndrome (DES is a medication that was given to women to prevent complications in pregnancy like premature birth or miscarriage. However, this medication has caused infertility in some of the children of mothers who took DES.).
A past ectopic (tubal) pregnancy.
How does age impact female infertility?
As a woman ages, her chances of becoming pregnant decreases. Age is becoming a more common factor in female infertility because many couples are waiting to have children until their 30s or 40s. Women over age 35 have a higher risk of having fertility issues. The reasons for this include:
DIAGNOSIS AND TESTS:
Your healthcare provider will need to know about your menstrual periods, any past pregnancies, miscarriages, pelvic pain, unusual vaginal bleeding or discharge. You may also be asked about any past pelvic infections or sexually transmitted infections (STIs). Some questions may include:
Have you had any previous pregnancies or miscarriages?
Is your menstrual cycle normal and regular or painful and irregular?
Do you have heavy bleeding or abnormal discharge?
Do you have any pelvic pain?
Have you had any abdominal surgeries in the past?
Blood tests: The type of lab tests will depend on your health history and what diagnoses your doctor is considering. Examples of lab tests include thyroid testing, prolactin, female hormone, progesterone,PID etc.
MANAGEMENT AND TREATMENT
How is female infertility treated?
Once your healthcare provider has diagnosed female infertility and pinpointed the cause, there are a variety of treatment options. The cause of the infertility guides the type of treatment. For example, structural problems may be treated through surgery, while hormonal medications can be used for other issues (ovulation issues, thyroid conditions).
PREVENTION
Can female infertility be prevented?
Most forms of female infertility can predicted or prevented. However, the risk factors that may contribute to infertility can, in some cases, be controlled to prevent this condition. For example, lifestyle modifications, such as reducing alcohol consumption and quitting smoking,
Infertility can be incredibly stressful.😭