Abuw Lubabah Chemist

02/07/2017

The effects of quinine and chloroquine antimalarial
treatments in the first trimester of pregnancy.
McGready R, et al. Trans R Soc Trop Med Hyg. 2002
Mar-Apr.
Show full citation
Abstract
Quinine (n = 246) was used to treat uncomplicated
Plasmodium falciparum and chloroquine (n = 130) was
used to treat P. vivax, in a total of 376 episodes of
malaria in the first trimester of pregnancy, in 300 Karen
women (Thailand, 1995-2000). Parasites were still
present on day 6 or 7 in 4.7% (11/234) of episodes
treated with quinine. The overall 28 day parasite
reappearance rate following quinine was 28.7%
(60/209) for primary treatments and 44% (11/25) for
re-treatments. Quinine treatment resulted in a high rate
of gametocyte carriage: person-gametocyte-weeks =
42.5 (95% CI 27.8-62.1) per 1000 woman-weeks. For
P. vivax, the reappearance rate for all episodes by day
28 was 4.5% (5/111). Significantly more women
complained of tinnitus following quinine treatment
compared to on admission: 64.5% (78/121) vs 31.6%
(59/187), P < 0.001. Using survival analysis, the
community rate of spontaneous abortion in women who
never had malaria in pregnancy, 17.8% (16.5-19.0), did
not differ significantly from rates in women treated with
quinine: 22.9% (95% CI 15.5-30.3), or chloroquine:
18.3% (95% CI 9.3-27.3), P = 0.42. Pregnancies
exposed to quinine or chloroquine and carried to term
did not have increased rates of congenital abnormality,
stillbirth or low birthweight. These results suggest that
therapeutic doses of quinine and chloroquine are safe
to use in the first trimester of pregnancy.
PMID: 12055810 [PubMed - indexed for MEDLINE]

12/06/2017

How can I reduce a fever during pregnancy without using medicine?

Suzanne Merrill-Nach

ob-gyn

Call your healthcare practitioner if you'repregnant and have a fever.

A temperature higher than 100.4 degrees Fahrenheit – or the illness causing the fever – could harm both you and your developing baby. A high fever increases the risk of birth defectsor miscarriage in early pregnancy. The higher the fever and the longer it lasts, the higher the risk.

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Once your doctor or midwife confirms that your fever is no cause for concern, you can decide how to handle it. If you want to lower your fever without using medicine like acetaminophen – or just don't have any on hand – you can try these methods:

Lie down and place a cool, damp washclothon your forehead.

Take a lukewarm tub bath or sponge bath. Avoid using cold water, since it can cause you to shiver, leading to a spike in temperature. Lukewarm water will work fine – your fever will fall as the water evaporates off your skin. (You may have heard that a sponge bath using rubbing alcohol will bring down a fever. Don't try this, as it can cool you down too quickly, prompting your body to reheat even further. Breathing in the vapors can be harmful, too.)

Drink plenty of fluids to stay hydrated and help cool your body from the inside out.

Turn on a fan. Don't let it blow directly on you, because that could cause you to become chilled. Instead, put it on a low setting and let it circulate the air around you.

Dress in one light layer of clothing. If you get chilled, wrap yourself in a light blanket until you're warm enough to remove it.

Stay indoors in a cool place. Or, if you're outside, stay in the shade.

Bringing your fever down won't cure your illness, but it can help you feel more comfortable and avoid dehydration.

19/02/2017

Measles is a highly contagious acute viral infection, transmitted by the airborne route (inhalation of respiratory droplets spread by infected individuals). The disease mainly affects children under 5yrs of age and can be prevented by immunization. So make sure your child is being immunized. Tnx.

14/03/2015

13/03/2015

SKELETON: Is the bony rigid framework that gives shapes, protection and support to certain delicate organs.

13/03/2015

The sciatic nerve is the largest nerve in the body. It is about 2cm wide at its origin. It passes through the greater sciatic foramen into the buttock then descends through the posterior aspect of the thigh supplying the hamstring muscles. At the level of the middle of the femur it divides to form the tibial and common peroneal nerves.

11/03/2015