Journal of Parkinson's Disease

20/02/2026

"Six months of regular aerobic exercise can partially “normalize” disrupted brain communication in people with Parkinson’s disease, a new Canadian study suggests. By cycling for an hour three times a week, patients saw shifts in their brain networks that moved in the opposite direction of the disease’s typical pattern, suggesting that exercise may help the brain reorganize circuits related to movement and balance. Read more:

"https://parkinsonsnewstoday.com/news/new-imaging-shows-exercise-helps-normalize-parkinsons-brain/

Aerobic exercise may help "normalize" brain networks in people with Parkinson's by reorganizing key dopamine circuits, a study suggests.

18/02/2026

APDA joins the nation in mourning the passing of Reverend Jesse Jackson, a civil rights leader whose lifelong dedication to justice, equality, and human dignity changed the course of history. We honor his life, his leadership, and his advocacy — and we extend our deepest condolences to his family, loved ones, and all who were touched by his work.

We are also grateful for the strength he showed in publicly sharing his initial Parkinson’s diagnosis, which was later determined to be Progressive supranuclear palsy (PSP). His openness helped reduce stigma, encouraged others to seek support, and brought greater awareness to the challenges faced by people living with Parkinson’s and PSP.

02/02/2026

"Parkinson’s disease patients face an uncertain path, with motor symptoms like tremors and rigidity worsening at wildly different rates. Neuroimaging has faltered in reliable forecasts, but a new study deploys an explainable ensemble machine learning model on baseline blood transcriptomics to predict this trajectory, offering clinicians a peripheral blood test for precision prognosis."

Read More: https://www.webpronews.com/blood-genes-unlock-parkinsons-motor-fate-explainable-ai-reveals-progression-secrets/

A groundbreaking explainable ensemble ML model uses PPMI baseline blood transcriptomics to forecast Parkinson's motor progression, surpassing neuroimaging with interpretable gene insights into immune and mitochondrial drivers.

15/01/2026

This new Blog entry explains how the filmmaking project "Who's Dancing Now?" grew into a shared creative effort between people with Parkinson s disease (PwPD), film creators, and healthcare staff. PwPD helped shape the story, appeared in the film, promoted it, and organized events, which gave them a stronger sense of control and emotional well-being. A survey after the film's release showed that participants felt more self-acceptance, resilience, and social connection. The project shows that creative teamwork can strengthen patient confidence and improve public understanding, supporting community-based Parkinson's care.

Read the full blog here: https://www.linkedin.com/pulse/jpd-blog-section-what-happens-when-patients-create-journal-vi4ye/?trackingId=bduZxMVglNF7Cif6fLHJIA%3D%3D

08/01/2026

We are proud to announce that Georgina M. Aldridge, Matthew Weber and Lauren Walker are this year's recipients of the Parkinson Prize for best articles published in basic and clinical science.

Congratulations to the winners! The winning articles are:

Basic Science Winner: Alpha-Synuclein Pre-Formed Fibrils Injected into Prefrontal Cortex Primarily Spread to Cortical and Subcortical Structures, by Matthew A. Weber, et al. (https://journals.sagepub.com/doi/full/10.3233/JPD-230129)

Clinical Science Winner: Prevalence of Concomitant Pathologies in Parkinson's Disease: Implications for Prognosis, Diagnosis, and Insights into Common Pathogenic Mechanisms, by Lauren Walker and Johannes Attems
(https://journals.sagepub.com/doi/full/10.3233/JPD-230154)

The full news explaining the importance of the articles, authors' bio's and runner's up can be found here: https://tinyurl.com/parkprize2025

02/01/2026

Webinar: A deeper look at young onset Parkinson’s, 28 January 2026, 5-6pm GMT, 12-1pm ET.

In this webinar, Edinburgh University’s Professor Tilo Kunath will be joined by an expert panel to discuss what YOPD is and how it differs from idiopathic (typical) Parkinson’s, as well as the potential genetic links. Furthermore, the panel will explore research opportunities for people with YOPD.

You can register to attend this webinar live at: https://cureparkinsons.org.uk/2025/12/webinar-a-deeper-look-at-young-onset-parkinsons/

Held in partnership with the University of Edinburgh and the Journal of Parkinson’s Disease, with Edinburgh University’s Professor Tilo Kunath as chair,

19/12/2025

JPD will attend the World Parkinson's Congress 2026 in Phoenix Arizona, with a booth presence in the exhibit hall. We are happy and proud to announce that the the congress abstracts will again be published in JPD. We look forward to connecting with many of you there! Note that early registration for the meeting runs until January 15: https://wpc2026.org/

What: 7th World Parkinson CongressWho is invited: All stakeholders in the Parkinson’s communityWhen: Sun., May 24 – Wed., May 27, 2026Where: Phoenix, Arizona, USAAddress: Phoenix Convention Center

08/12/2025

DECEMBER ISSUE: https://journals.sagepub.com/toc/pkna/15/8

This issue includes Review article "Beyond the brain: The colorectal impact of Parkinson's disease" by Khan et al.

And a new entry of the special section Advice to People with Parkinson's in my Clinic on "How to manage running-induced dystonia", by Callisaya et al.

Table of contents for Journal of Parkinson’s Disease, 15, 8

08/12/2025

New groundbreaking article: A PLAN to address the Parkinson pandemic, by Dorsey at al.

"Parkinson's is one of the world's fastest growing brain diseases, and most of it is preventable. Adjusted for age, the prevalence of Parkinson's has increased 60% over the last thirty years. Chemicals in our food, water, and air are helping fuel its rise. Many of these are inhaled (come in through the nose) or ingested (enter through the gut). To address the Parkinson pandemic, we propose a “PLAN” to (1) Prevent the disease; (2) Learn why it starts; (3) Amplify the voices of those affected; and (4) Navigate the frontier of new treatments. By doing so, we can reach bold goals by 2035..."

Read more: https://journals.sagepub.com/doi/full/10.1177/1877718X251378115

The Parkinson pandemic continues to spread. Almost 12 million individuals now have the disease, nearly double the estimate from just six years ago. Its human-ma...

06/10/2025

New to Read: A Review article on "Care partner needs in Parkinson's disease: A systematic review of qualitative and quantitative data" by Hulshoff et al. This study looks into understanding the needs of care partners for persons with Parkinson's disease (PD), and how to ease their burden and help with their important role.

Background Care for persons with Parkinson's disease (PD) is to a great extent carried out by care partners. It is important to understand their needs to e...

03/10/2025

“We know that there are a variety of different biological drivers that potentially influence Parkinson’s, and so the aim of this funding call is to increase the odds in our favour for identifying a disease-modifying therapy for Parkinson’s by targeting different aspects of the condition. We hope that this will pave the way for future success and help us to find a cure more quickly.” – Dr Simon Stott, Director of Research

Exciting announcement! We are now accepting expressions of interest for our new £2 million funding call to encourage the testing of rationally designed combinations of two or more drugs with disease-modifying potential for Parkinson’s.

Researchers interested in applying will need to submit an expression of interest by 24 November to be considered. These will be reviewed internally, and those within our funding remit will be invited to submit a full application.

Find out more: https://buff.ly/PowBxQZ

03/10/2025

New Quarterly Webinar: Deep Brain Stimulation (DBS) for Parkinson's: The next steps.

Deep Brain Stimulation (DBS) is a surgical treatment for Parkinson’s that involves implanting electrodes in the brain. These electrodes produce electrical impulses that stimulate brain activity, which can help relieve Parkinson’s motor symptoms.

Presented by Edinburgh University, Journal of Parkinson’s Disease and Cure Parkinson’s, this edition focuses on DBS, with a special emphasis on an emerging form of this therapy: adaptive DBS. Edinburgh University’s Professor Tilo Kunath is joined by an expert panel to discuss what DBS is, how the therapy works and interacts with the brain, and whether DBS, especially adaptive DBS, could have a disease-modifying effect.

https://youtu.be/deBhcW-CbQQ

Deep Brain Stimulation (DBS) is a surgical treatment for Parkinson’s that involves implanting electrodes in the brain. These electrodes produce electrical im...