Journal of Huntington's Disease

09/01/2026

✨ Welcome to 2026! ✨

As we move into the new year, we’re reflecting on how to make our social media spaces more engaging, inclusive, and meaningful for our global community. 🌏💡

We’d love to hear from you: how do you like to engage with academic content online? What formats, topics, or types of discussion would make you most excited to interact with us this year? Your input will help shape content that connects and inspires across borders.

Share your thoughts in the comments, we can’t wait to learn from you! 💬

22/12/2025

As the year comes to a close, we’d like to wish everyone in the global Huntington’s disease community a peaceful holiday season.

We’re incredibly grateful to people with Huntington’s, their loved ones, advocates, researchers, and clinicians who continue to share knowledge and hope throughout the year.

Wishing you moments of rest, connection, and kindness, wherever you are in the world. 💙✨

Happy Holidays from all of us.

15/12/2025

🧠 Caring for people with HD (PwHD) can be incredibly challenging.

💜 Caregivers play a vital role in supporting PwHD, however, providing this support often comes with significant pressures.

A recently published review article brought together evidence from across the literature to explore what shapes the challenges faced by caregivers of PwHD. This included:

• The severity of symptoms experienced by the PwHD
• The availability of external support
• The caregiver’s own mental health

🚨 These findings highlight the urgent need for targeted support services and interventions that recognise and respond to the specific needs of caregivers for PwHD.

📖 See more details here: https://journals.sagepub.com/doi/full/10.1177/18796397251377237

01/12/2025

📏 How do we choose the “right” way to measure symptoms in Huntington’s disease (HD)?

Each approach, whether it’s self-report from people with HD (PwHD), clinician-rated assessments, or performance-based tests, offers a different piece of the picture. Understanding the strengths and limitations of these tools helps us make more informed decisions in both research and clinical care.

A recent study explored how these different types of measures compare, shedding light on where they align and where they diverge.

🔍 What the study found:
• PwHD self-reporting symptoms aligned strongly with how clinicians rated their motor symptoms, sleep/fatigue, and mental health.
• However, the alignment between self-reporting symptoms and clinician ratings was weaker for speech, swallowing, and cognitive symptoms.
• When PwHD self-reported symptoms this showed very minimal relationships with performance-based tests (e.g. wearable device-based estimates of sleep and activity).

💬 How do you think we should capture the full picture of Huntington’s disease? Leave your thoughts in the comments below.

🔗 See more details here: https://journals.sagepub.com/doi/full/10.1177/18796397251366313

24/11/2025

💜 Recognising emotions may become difficult for people with Huntington’s disease (PwHD).

A new review that looked at studies from January 1993 until January 2025 shows that identifying angry, fearful, disgusted, and sad facial expressions may be difficult for people with manifest (symptomatic) HD. However, identifying happy or neutral faces appeared to be fine.

Understanding this can help families, friends, caregivers, and healthcare professionals make sense of everyday changes for PwHD.

Have you seen this in your HD journey, whether personally, professionally, or as a caregiver?

🔗 To read more about this review, follow the link: https://journals.sagepub.com/doi/10.1177/18796397251390252

18/11/2025

The Journal of Translational Science in Rare Diseases has an open call for a new Editor in Chief. Read more here regarding the profile requirements and how to apply:

Subscription and open access journals from Sage, the world's leading independent academic publisher.

17/11/2025

The Journal of Huntington's Disease is pleased to share that a new Social Media Editor has joined our team. We look forward to enhancing our updates, sharing highlights from current and upcoming issues, and engaging more actively with our community.

Thank you for continuing to follow and support our journal.

28/10/2025

Call for Papers: The Journal of Huntington's Disease is calling for original research or review papers on the role of exercise and physical activity in HD, to be considered for a special edition. The submission deadline is March 1, 2026. More details on the scope and guest editors is available at: https://tinyurl.com/JHDexercise

Subscription and open access journals from Sage, the world's leading independent academic publisher.

07/10/2025

NEW TO READ: The Abstracts of the 1st Biennial Huntington's Disease Clinical Research Congress, October 11-13, 2025, Nashville, TN. The meeting advances clinical research and care in HD.

https://journals.sagepub.com/toc/huna/14/1_suppl

Table of contents for Journal of Huntington's Disease, 14, 1_suppl

30/09/2025

One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

11/09/2025

NEW RELEASE: Special Issue on Glia and Non-Neuronal Cells in Huntington's Disease!
➡️Guest Edited by Mahmoud Pouladi and Asa Petersen
📷Drs. Pouladi and Petersen have compiled a compendium of new reviews on the current state of our understanding of glia and non-neuronal cells and neuroinflammation in HD as well as the gaps in our knowledge, areas of research that would expand our knowledge, and how we might tackle therapeutics in light of dysregulation of these cell types and their interactions with neurons.
📷Read all paperps: https://journals.sagepub.com/toc/huna/14/3

Table of contents for Journal of Huntington's Disease, 14, 3

25/07/2025

Announcing the release of Journal of Huntington's Disease Volume 14, Issue 2! ➡️
📷New Clinical Trials Corner
📷 Review Article on Performance-based functional capacity measures and their suitability for clinical trials
📷And more:

Table of contents for Journal of Huntington's Disease, 14, 2