09/07/2021
Onderzoek naar het effect van trilling op tissue....langzaam maar zeker verschuift het huidige paradigma.
🔄 Exciting to finally see this research being conducted! TYPE 'YES' if you agree!--STANFORD RESEARCHERS DOCUMENTING EFFECTS OF SOUND FREQUENCIES ON HEART CELLS--
Heart cells are among the most densely packed in the body — about 100 million fit into a space the size of a sugar cube. The compact structure crams the cells so close together that they can communicate with one another and beat as one lump. For tissue engineers, however, it poses a tricky hurdle: Pack the cells too tightly and some won’t get proper nutrients; too loosely and they can’t coordinate a beat.
Cardiologist Sean Wu, MD, PhD, had been probing the problem when he met Utkan Demirci, PhD, an acoustic bioengineer and professor of radiology. “Utkan brought up this idea that we could use acoustics to pack the cells very densely and still maintain an ability to control and tune their organization — and we got really excited,” says Wu, associate professor of medicine.
Demirci’s idea exploits a type of acoustic signal that creates Faraday waves, which result from a physical perturbation at the interface of liquid and air (if you’ve ever flown in a turbulent plane with a beverage, you’ve witnessed Faraday waves in your cup). The waves cause ripples in the liquid, and anything floating in the liquid sloshes around too.Demirci and Sean Wu use acoustics to manipulate heart cells into intricate patterns. A simple change in frequency and amplitude puts the cells in motion, guides them to a new position and holds them in place.