
12/06/2025
Arnica Montana
Arnica montana is a popular traditional remedy widely used in complementary medicine for its wound-healing properties.
To understand the action of Arnica in wound healing, researchers in Italy evaluated the whole plant extract, in a wide range of dilutions, on THP-1 human cells, differentiated into mature macrophages and into an alternative IL-4-activated phenotype involved in tissue remodeling and healing.
Their findings?
"On macrophages differentiated towards the wound healing phenotype, A. montana affected the expression of several genes. This exploratory study provides new insights into the cellular and molecular mechanisms of action of A. montana as a promoter of healing, since some of the genes it modifies are key regulators of tissue remodelling, inflammation and chemotaxis."
Source: Olioso, D et al. Arnica montana effects on gene expression in a human macrophage cell line. Evaluation by quantitative Real-Time PCR Homeopathy, May, 2016 Volume 105 Issue 2, pages 131-147.