17/04/2023
From Petri Dishes to Chips: How Biochemical Assays Enhance Organ-on-Chip Technology is the title of Flavio Bonanini's talk at this year's (which is on Tuesday, 25 April 2023 in Antwerp, Belgium or online).
From 2019, Flavio has been a Marie Sklodowska-Curie fellow student affiliated with MIMETAS, a biotech company located in Leiden, Netherlands, as part of the PoLiMeR consortium. His current focus is on liver models and contributes to the development of a throughput-capable organ-on-chip culture platform, which MIMETAS specialises in developing and commercialising.
The successful translation of pre-clinical research results into clinical practice remains a significant challenge for the pharmaceutical industry. Clinical trials often fail, have limited efficacy, or induce toxic side effects that were not anticipated. This is in part due to inadequate pre-clinical models, such as two-dimensional cell cultures, which do not mimic the complex environment cells find in vivo. Recent advances in organ-on-a-chip technology offer a promising avenue to model important aspects of human physiology in vitro.
MIMETAS' OrganoPlate® is an organ-on-a-chip platform that allows for controlled and complex cultivation of cellular systems in three dimensions, mimicking architecture, mechanical properties, cellular composition and biochemical functionalities of healthy and diseased organs. The integration of organ-on-a-chip technology and reliable assays could transform pre-clinical drug development by providing accurate and predictive models of human physiology.
Discover more during this year's Discover Glo. There are a few places left you will need to book on our website to secure a place at: https://bit.ly/3UJoGOi