Maastricht Clinical Neuro Imaging

23/07/2024

On the merits and potential of advanced neuroimaging techniques in COVID-19: A scoping review
Noa van der Knaap et al. Neuroimage Clin. 2024.

01/07/2020

To those interested, thank you so much for liking this page!
My research focuses on the application of advanced MRI methodology and analysis methods in cognitive and other neurological disorders.
Although I'm more active on twitter (https://twitter.com/jfajansenphd), I occasionally update this page as well. Today, I'd like to refer you to my website, in which I list my main topics and some highlights.
https://www.jansenjfa.com/research/

Some of my favorite topics include Neurotransmitter MR Spectroscopy, Advanced Diffusion Models, High Field MR, and Myelin Imaging.

Thanks!

My research focuses on the application of advanced MRI methodology and analysis methods in cognitive and other neurological disorders. Click on the topics for some highlights (for complete list see Publications)

12/05/2020

The last chapter from Gerald’s PhD thesis made it to pubmed. The work described in this article was based on the MSc project from Floor Fasen, who was supervised by Gerald. We investigated the brain functional networks of children with Childhood Absence Epilepsy, and it was published in our frequent journal: Neuroimage Clinical. Enjoy!

While cognitive impairments are not generally considered to be part of the childhood absence epilepsy (CAE) syndrome, some recent studies report cognitive, mainly attentional, deficits. Here we set out to investigate the whole brain functional network of children with CAE and controls. Furthermore,....

09/04/2020

Geralds latest work, which combines Myelin imaging with DTI has also been published:

Constructing an Axonal-Specific Myelin Developmental Graph and Its Application to Childhood Absence Epilepsy
Gerhard S Drenthen et al. J Neuroimaging. 2020

https://onlinelibrary.wiley.com/doi/full/10.1111/jon.12707

On February 7th 2020 Gerald Drenthen succesfully defended his PhD thesis, in which he developed myelin MRI imaging techniques and applied these to children with absence epilepsy. These are some of his recent publications:

A new analysis approach for T2 relaxometry myelin water quantification: Orthogonal Matching Pursuit. Drenthen, G. S.; Backes, W. H.; Aldenkamp, A. P.; Op 't Veld, G. J.; and Jansen, J. F. A. Magn Reson Med, 81(5): 3292-3303. 2019.
http://www.ncbi.nlm.nih.gov/pubmed/30444019

Applicability and reproducibility of 2D multi-slice GRASE myelin water fraction with varying acquisition acceleration. Drenthen, G. S.; Backes, W. H.; Aldenkamp, A. P.; and Jansen, J. F. A. Neuroimage, 195: 333-339. 2019.
http://www.ncbi.nlm.nih.gov/pubmed/30965132

Lower myelin-water content of the frontal lobe in childhood absence epilepsy. Drenthen, G. S.; Fonseca Wald, E. L. A.; Backes, W. H.; Debeij-Van Hall, M. H. J. A.; Hendriksen, J. G. M.; Aldenkamp, A. P.; Vermeulen, R. J.; Klinkenberg, S.; and Jansen, J. F. A. Epilepsia, 60(8): 1689-1696. 2019.
http://www.ncbi.nlm.nih.gov/pubmed/31283841

On the merits of non-invasive myelin imaging in epilepsy, a literature review
Gerhard S Drenthen, Walter H Backes, Albert P Aldenkamp, R Jeroen Vermeulen, Sylvia Klinkenberg, Jacobus F A Jansen
Journal of Neuroscience Methods
Volume 338, 15 May 2020, 108687
https://www.sciencedirect.com/science/article/pii/S0165027020301096

30/03/2020

On February 7th 2020 Gerald Drenthen succesfully defended his PhD thesis, in which he developed myelin MRI imaging techniques and applied these to children with absence epilepsy. These are some of his recent publications:

A new analysis approach for T2 relaxometry myelin water quantification: Orthogonal Matching Pursuit. Drenthen, G. S.; Backes, W. H.; Aldenkamp, A. P.; Op 't Veld, G. J.; and Jansen, J. F. A. Magn Reson Med, 81(5): 3292-3303. 2019.
http://www.ncbi.nlm.nih.gov/pubmed/30444019

Applicability and reproducibility of 2D multi-slice GRASE myelin water fraction with varying acquisition acceleration. Drenthen, G. S.; Backes, W. H.; Aldenkamp, A. P.; and Jansen, J. F. A. Neuroimage, 195: 333-339. 2019.
http://www.ncbi.nlm.nih.gov/pubmed/30965132

Lower myelin-water content of the frontal lobe in childhood absence epilepsy. Drenthen, G. S.; Fonseca Wald, E. L. A.; Backes, W. H.; Debeij-Van Hall, M. H. J. A.; Hendriksen, J. G. M.; Aldenkamp, A. P.; Vermeulen, R. J.; Klinkenberg, S.; and Jansen, J. F. A. Epilepsia, 60(8): 1689-1696. 2019.
http://www.ncbi.nlm.nih.gov/pubmed/31283841

On the merits of non-invasive myelin imaging in epilepsy, a literature review
Gerhard S Drenthen, Walter H Backes, Albert P Aldenkamp, R Jeroen Vermeulen, Sylvia Klinkenberg, Jacobus F A Jansen
Journal of Neuroscience Methods
Volume 338, 15 May 2020, 108687
https://www.sciencedirect.com/science/article/pii/S0165027020301096

21/01/2020

We are recruiting a new PhD student on ultra-high field (7.0T) MRI in epilepsy.

The School for Mental Health and Neuroscience has a vacancy for a PhD student 4 years Project title: Value of Ultra High field MRI for focal epilepsy (EpiUltra study)

13/01/2020

The official press release (in Dutch) for our Horizon2020 grant capture, in which we will investigate heart failure and vascular dementia with advanced MRI techniques.

Nieuws | 13 januari 2020 Onderzoek naar gedeelde oorzaak hartfalen en vasculaire dementie Actueel › Nieuws › Onderzoek naar gedeelde oorzaak hartfalen en vasculaire dementie Europese miljoenensubsidie voor onderzoek naar de kleinste bloedvaatjes in hart en breinWetenschappers van het Maastricht ...

03/11/2019

https://m.limburger.nl/cnt/dmf20191101_00130680/hersenen-worden-sneller-ouder-door-diabetes

Diabetes maakt hersenen sneller ouder. Dit blijkt uit een studie naar ruim tweeduizend MRI-scans in het MUMC. Het ziekenhuis hoopt vooral dat mensen met pr...

02/11/2019

Some local media attention (De Limburger, Nov 2nd ‘19) for our recent work in Diabetes Care https://care.diabetesjournals.org/content/early/2019/10/09/dc19-0762.long

18/09/2019

Very happy with this one, our work on white matter connectivity in prediabetes and T2DM has been accepted in Diabetes Care (IF 15.27), a new high for me 🤗

05/09/2019

Very happy with this one, after inspiration from Vera Keil at the 2015 ISMRM, we are now able to show the merits of the spectral diffusion analysis in disease:
Spectral Diffusion Analysis of Intravoxel Incoherent Motion MRI in Cerebral Small Vessel Disease https://onlinelibrary.wiley.com/doi/full/10.1002/jmri.26920

15/08/2019

It took some perseverance, but our spectral IVIM work in cSVD has finally found its home in JMRI 😉