CombiBreed - English

CombiBreed - English Discover all about your pet with our genetic tests! From identifying breeds to disorders and traits.

Glycogen Storage Diseases (GSDs) are a group of metabolic disorders caused by defects in glycogen-processing enzymes. Th...
09/03/2026

Glycogen Storage Diseases (GSDs) are a group of metabolic disorders caused by defects in glycogen-processing enzymes. This test detects a mutation in the RBCK1 gene, linked to Polyglucosan Body Myopathy Type 1 (PGBM1) in Basset Hounds. The mutation leads to accumulation of abnormal glycogen (polyglucosan bodies) in muscle and cardiac tissue and is inherited in an autosomal recessive manner.

Affected dogs typically develop progressive muscle weakness, reduced exercise tolerance, and heart problems between 3 and 6 years of age. Cardiac glycogen buildup can cause cardiomyopathy, sometimes leading to sudden collapse or death. Early signs may be subtle, including lethargy, mild exercise intolerance, or respiratory difficulties.

This new test is available under test code H113.

Cerebellar Ataxia (CA) is a hereditary neurological disorder affecting the cerebellum, the part of the brain responsible...
06/03/2026

Cerebellar Ataxia (CA) is a hereditary neurological disorder affecting the cerebellum, the part of the brain responsible for coordination, balance, and fine motor control. In Flat-Coated Retrievers, a genetic variant disrupts normal neuronal function, impairing signal transmission between nerve cells and causing a gradual loss of coordinated movements. Affected dogs show typically loss of coordination (ataxia), a unsteady or “drunken” gait, head tremors, and difficulty with precise movements such as jumping, turning, or navigating stairs. Clinical signs usually appear in young puppies and progressively worsen over time.

This new test is available under test code H117.

This combination package for the American Akita is completely new!This Combination Pack is designed to provide you with ...
04/03/2026

This combination package for the American Akita is completely new!

This Combination Pack is designed to provide you with vital insights into your dog’s genetic health, traits and diversity and includes DNA tests for numerous important diseases and/or traits. In addition, we also calculate the Coefficient of Inbreeding (COI) and the percentage of Heterozygosity of your dog’s DNA. The COI shows the degree of inbreeding of your dog, whereas the Heterozygosity percentage is a measure of your dog’s individual genetic diversity.

This new test is available under test code H111.

Obesity is a common health concern in dogs. While factors like diet, exercise, and lifestyle all play important roles in...
02/03/2026

Obesity is a common health concern in dogs. While factors like diet, exercise, and lifestyle all play important roles in a dog’s weight, genetics also have a significant influence. A mutation in the gene DENND1B has been associated with an increased risk of obesity. This gene plays an important role in a brain signaling system that helps regulate appetite and energy balance (known as MC4R). When this system is disrupted, it can lead to increased hunger and reduced energy use, both of which promote weight gain. Obesity is not caused by DENND1B alone. Multiple genes, along with environmental factors, influence a dog’s weight.

This new test is available under test code: H172.

Achromatopsia is an eye disorder that can cause day blindness, sensitivity to light and a loss of colour vision. This pa...
27/02/2026

Achromatopsia is an eye disorder that can cause day blindness, sensitivity to light and a loss of colour vision. This particular form of the disorder is known as Achromatopsia-3, and is caused by a recessive mutation to the gene CNGB3. Affected dogs generally begin displaying symptoms of day blindness and photophobia (sensitivity to bright light) between the ages of 8 and 12 weeks. Only the dog’s bright-light vision is affected, vision remains normal in dim light.

This new test is available under test code H904 and has been added to the CombiBreed package for the Australian Shepherd test code H321.

A mutation in the KIT gene causes the white spotting coat pattern known as Dominant White 21 (W21) in horses. This autos...
25/02/2026

A mutation in the KIT gene causes the white spotting coat pattern known as Dominant White 21 (W21) in horses. This autosomal dominant mutation can range from small white markings to an entirely white coat. In Icelandic horses, W21 typically features a predominantly white face with speckles and irregular white patches across the body, most noticeable on the legs and belly.

This new test is available under test code P342.

REM sleep behaviour disorder (RBD) is a neurological condition observed in Russian Blue cats. It is caused by a mutation...
22/02/2026

REM sleep behaviour disorder (RBD) is a neurological condition observed in Russian Blue cats. It is caused by a mutation in the FAM8A1 gene. Symptoms of RBD in Russian Blue cats typically appear during adolescence or early adulthood, and their severity can vary between individuals. RBD episodes may progressively worsen over time. Early episodes can be mild and sporadic, including brief muscle twitches, sudden movements, or vocalizations during sleep. As the condition progresses, episodes may become more severe and frequent. Urinary issues can also occur, such as urinary retention, where the cat has difficulty fully emptying the bladder, sometimes leading to overflow incontinence or an enlarged bladder.

This new test is available under test code K342.

Ensure the genetic health of your breeding dogs with our comprehensive DNA Health Package. This package provides an in-d...
19/02/2026

Ensure the genetic health of your breeding dogs with our comprehensive DNA Health Package. This package provides an in-depth analysis of your dog’s genetic profile, offering valuable insights into health issues and hereditary traits. Screen for key hereditary conditions relevant to your breed, make informed pairing decisions, and support responsible breeding for a healthy future. A valuable tool for every dedicated dog breeder.

This test is available under test code: H860.

LAST CHANCE!Love is in our DNA!🧬A gift that truly matters this Valentine’s Day - personal, valuable, and meaningful.Get ...
13/02/2026

LAST CHANCE!

Love is in our DNA!🧬

A gift that truly matters this Valentine’s Day - personal, valuable, and meaningful.
Get a 10% discount on almost all DNA tests in the webshop.

Discount valid until 15 February 2026.
Not valid in combination with other discounts.

Note: Random parentage tests are excluded from this discount.

This combination package for alpacas is completely new! 🦙The A-locus (ASIP gene) plays a crucial role in producing coat ...
13/02/2026

This combination package for alpacas is completely new! 🦙

The A-locus (ASIP gene) plays a crucial role in producing coat patterns, contributing to the diversity of coat colours and patterns observed in alpacas. It influences where on the hair and body each of the two pigments, eumelanin (black/brown) and phaeomelanin (red/yellow) is expressed. A mutation in the A-locus typically results in a darker coat colour.

The E-locus contains the MCR1-gene and plays also a crucial role in coat patterns and colour. It determines whether eumelanin can be produced, and mutations here typically result in a lighter coat colour.

Together, the A-locus and E-locus interact to create the incredible variety of alpaca coat colours and patterns we see. Overall coat colour is also influenced by other factors, like Classic Grey, which adds even more diversity.

Polioencephalopathy is a hereditary neurological disorder that affects the grey matter of the brain, leading to movement...
12/02/2026

Polioencephalopathy is a hereditary neurological disorder that affects the grey matter of the brain, leading to movement abnormalities and progressive motor dysfunction. In Eurasier dogs, this condition has been linked to a mutation in the MECR-gene, which plays an important role in normal cellular metabolism. When this gene does not function properly, nerve cells in the brain cannot maintain normal metabolic processes, resulting in neurological impairment. The condition is inherited in an autosomal recessive manner.

This new test is available under test code H130 and has been added to the CombiBreed package for the Eurasier under test code H120.

Love is in our DNA!🧬A gift that truly matters this Valentine’s Day - personal, valuable, and meaningful.Get a 10% discou...
12/02/2026

Love is in our DNA!🧬

A gift that truly matters this Valentine’s Day - personal, valuable, and meaningful.
Get a 10% discount on almost all DNA tests in the webshop.

Discount valid until 15 February 2026.
Not valid in combination with other discounts.

Note: Random parentage tests are excluded from this discount.

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