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CombiBreed - English

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CombiBreed - English

Discover all about your pet with our genetic tests! From identifying breeds to disorders and traits.

19/08/2025

🔬🧬Disproportionate Dwarfism is an inherited skeletal disorder in Dalmatians, caused by an autosomal recessive mutation in the PRKG2 gene. The condition results in shorter limbs in proportion to the body, while the torso and head remain normally shaped.

This test is available under test code H149 and has also been added to the Dalmatian breed package under test code H540.

14/08/2025

🧬Cerebellar Ataxia is an inherited neurological disorder caused by an autosomal recessive mutation in the RALGAPA1 gene. This mutation disrupts normal brain development and signal transmission, leading to coordination problems, tremors, and balance issues from around four weeks of age.

👉This new test is available under test code H156 and has been added to the CombiBreed package for the Belgian Shepherd under test code H513.

13/08/2025

Canine Multiple System Degeneration (CMSD) is a progressive neurological disorder involving degeneration across multiple regions of the central nervous system. Clinical signs usually appear between 10 and 14 weeks of age and include intention tremors, cerebellar ataxia, hypermetria, and impaired balance, often resulting in frequent falls. Due to the severity and progression of symptoms, most affected dogs are euthanized between 12 and 24 months to prevent further suffering.

Carrier status can be identified through DNA testing with our DNA test for CMSD in Chinese Crested Dogs (test code H165). This test is also part of the CombiBreed package for Chinese Crested Dogs with test code H514.

07/08/2025

Spastic Ataxia is an inherited neurological disorder in the Great Pyrenees, caused by a mutation in the SACS gene.The disease affects long nerve fibers, leading to coordination problems, muscle stiffness, and weakness in the hind limbs. Symptoms typically appear around 4 months of age and progressively worsen over time. Due to the gradual decline in mobility and quality of life, many affected dogs are euthanized between the ages of 4 and 7.

The test is available under test code H157 and has been included in both CombiBreed Great Pyrenees and the CombiBreed ‘Breeding Healthy Pets’ package for Belgium. This package is exclusively available at www.combibreed.com.

06/08/2025

In our webshop, we offer CombiBreed packages for many breeds. These packages include relevant DNA tests tailored to each breed.
Is your breed not listed? Let us know what you need — we’d love to hear from you!

TIP: Did you know you can also create your own package in our webshop? This allows you to order the DNA tests you want at a discounted package rate.

01/08/2025

Ensure the genetic health of your breeding cats with our comprehensive DNA Health Package. Screen for key hereditary diseases relevant to your breed, make informed pairing decisions, and support responsible, future-proof breeding. A valuable tool for every dedicated cat breeder.

30/07/2025

🧬Retinopathy with Vitamin E Deficiency (RVED), also known as Ataxia with Vitamin E Deficiency (AVED), is a hereditary neurological disorder seen in English Cocker Spaniels. It is caused by an autosomal recessive mutation - now identifiable with CombiBreed DNA test - that results in a loss of protein function and subsequent vitamin E deficiency. This deficiency can lead to retinal degeneration and vision impairment, and may also cause neurological symptoms in some cases.

👉This DNA test is available as a single test with testcode H164 or as part of the package CombiBreed English Cocker Spaniel (test code H598) or CombiBreed English Cocker Spaniel + AON (test code H273).

28/07/2025

🧬 The disease typically begins between 10 and 12 weeks of age, presenting as clusters of epileptic seizures - often occurring during sleep - and progresses rapidly, leading to severe neurological decline. Seizures are generally unresponsive to medication, and affected kittens are often euthanized at a young age due to poor prognosis.

The test is available under test code K339 and has been added to CombiBreed Bengal (test code K875).

25/07/2025

This test is available under test code H163 and includes five variants. It has also been added to the Welsh Corgi Pembroke panel (test code H584).

23/07/2025

👉🧬Swab collection: Follow the provided instructions carefully

As soon as we receive a swab, the DNA isolation process begins. For accurate and successful genetic testing, a sufficiently high DNA concentration is required. Sample collection is the most critical step in this process. It is therefore essential that the swab is taken correctly, following the provided instructions - this means swabbing firmly along the inner cheek lining, not just lightly on the surface.

If the DNA yield is too low, you will need to submit a new swab. This leads to delays, additional work, and possibly another visit to the veterinarian. Proper collection prevents these issues and ensures a smooth, reliable test result.

21/07/2025

🧬The condition is caused by impaired drainage of eye fluid, which damages the optic nerve and retina. Symptoms include dilated pupils, red eyes, a cloudy cornea, and possible behavioural changes due to pain.

👉The test is available under test code H906 and is included in the Basset Hound package under test code H525.

18/07/2025

🧬🐶This condition is caused by a mutation in the vWF gene and can lead to spontaneous bleeding, even without injury. Symptoms range from nosebleeds to life-threatening internal bleeding.

👉This new test is available with test code H167 and has also been added to the CombiBreed package for the Shetland Sheepdog with test code H586.

Adres

Agro Business Park 100
Wageningen
6708PW

Openingstijden

Maandag	08:00 - 16:30
Dinsdag	08:00 - 16:30
Woensdag	08:00 - 16:30
Donderdag	08:00 - 16:30
Vrijdag	08:00 - 16:30

Telefoon

+31317416402

Website

https://www.combibreed.com/

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