23/07/2025
चक्कर लाग्ने रोग र उपचार ।
Clinical Case – Metronidazole-Induced Dizziness (With Polypharmacy Insight)
👩⚕️ A female patient in her early 30s, obese, with type 2 diabetes, presented with sudden onset of severe dizziness and headache.
Neurological and vestibular examination were unremarkable, and brain MRI showed no abnormalities.
🧪 Blood glucose levels were within normal range at the time of symptoms. There were no signs of diabetic complications or orthostatic hypotension.
🦷 She had been suffering from a dental infection with a draining abscess. Following multiple consultations with general practitioners and dentists, she received several overlapping prescriptions — all of which included metronidazole. The patient ended up taking more than 6 tablets daily for several consecutive days.
🟢 Notably, her symptoms began to improve after stopping metronidazole.
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🧠 Clinical Interpretation:
This presentation is highly suggestive of metronidazole-induced central dizziness, despite the absence of MRI abnormalities. While classic metronidazole neurotoxicity can show T2/FLAIR hyperintensities in areas like the dentate nuclei, such radiologic findings are not mandatory for diagnosis. The strong temporal relationship, in addition to symptom improvement post-discontinuation, supports the diagnosis.
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📌 Personal Clinical Insight – Polypharmacy as an Overlooked Cause:
> In my clinical experience, one of the most underestimated causes of dizziness is polypharmacy — even when the drugs involved are intended to treat dizziness itself.
This case reinforces how patients — especially those with chronic conditions like diabetes — often see multiple providers, accumulating redundant or interacting medications.
I’ve encountered multiple cases where withdrawal of unnecessary drugs (including antivertigo medications, sedatives, or antibiotics like metronidazole) led to dramatic improvement in balance and clarity.
🧠 Medication review should always be a core part of dizziness assessment.