Pharma Helper

26/12/2024

22/12/2024

.Stem Cell
These are undifferentiated cells that have the potential to become a variety of blood cells. They initially become:
Myeloid Stem Cells
Lymphoid Stem Cells
Dendritic Cells (via various intermediate cells)


Myeloid Stem Cells
Myeloid stem cells become:

Megakaryocytes that produce platelets
Reticulocytes become:
Red Blood Cells (RBCs)
Promyelocytes become:
Monocytes – Macrophages
Neutrophils
Eosinophils
Mast Cells
Basophils


Lymphoid Stem Cells
Lymphoid Stem Cells travel to the thymus gland and differentiate into:

B lymphocytes (B cells) (mature in the bone marrow) that differentiate into:
Plasma Cells
Memory B Cells
T lymphocytes (T cells) (mature in the thymus) that differentiate into:
CD4 cells (T helper cells)
CD8 cells (Cytotoxic T Cells)
Natural Killer Cells


Megakaryocytes

Large cells
Big lobulated nucleus
Produce platelets
Platelets are essential for blood clotting


Reticulocytes

Immature red blood cells
Remnant RNA material called reticulum in cytoplasm
Released from bone marrow
Normally 1% of red blood cells are reticulocytes
Higher percentage indicates rapid turnover of blood, such as in:
Acute blood loss
Haemolysis
Loose their reticulum after a few days – becoming:


Red Blood Cells (RBCs)

RBCs contain large quantities of haemoglobin, and carry oxygen from the lungs to the tissues
They survive about 3 months


Macrophages

Monocytes circulate the blood stream
Enter tissues and differentiate into macrophages
Live in most tissues in the body
Have “Toll-Like Receptors“
Recognise “Pathogen-associated molecular patterns” (PAMPs)
Kill pathogens and abnormal cells by phagocytosis
Release cytokines that initiate the inflammatory response
Activate the other cells of the immune system


Neutrophils

Circulate through the blood and lymphatic system
Migrate to areas of inflammation
Kill pathogens and abnormal cells by phagocytosis


Eosinophils

Important in responding to parasites
They normally sit waiting in tissues
Contain granules

09/12/2024

Koshi province loksewa pharmacy supervisor syllabus 2081/82

09/12/2024

Koshi province pharmacy supervisor loksewa vacancy 2081/82.

02/12/2024

लोक सेवा आयोग, काठमाडौं कार्यालयको बिज्ञापन नं. १२०५७-१२०६२/०८०-८१ (खुला/समावेशी), स्वास्थ्य सेवा, फार्मेसी समूह, पाँचौ तह, फार्मेसी सहायक पदको लिखित नतिजा

20/11/2024

Notice: pharmacists and assistant pharmacists should be on Appron!

19/11/2024

Civil service hospital pharmacy supervisor result(सिमित)2080/81

16/11/2024

लोक सेवा आयोग, पोखरा कार्यालयको बिज्ञापन नं १२९७४/०८०-८१ (महिला), स्वास्थ्य सेवा, फार्मेसी समूह, पाँचौं तह, फार्मेसी सहायक पदको लिखित नतिजा

15/11/2024

Result of dipayal office:- pharmacy supervisor fifth level 2080/2081

25/03/2024

Ephedra:
Synonyms: Ma-huang , tsaopen Ma-huang
Botanical name: Ephedra sinica
Parts used: dried stem or aerial parts
Family: ephedraceae
Chemical constituents: ephedrine(main constituents)
Pseudoephedrine, norephedrine
Uses:
- expectorant and demulcent
-relieves in rhinitis , whooping cough, and hay fever

22/03/2024

Glycosides Tricks to remember:
DiLiP SARD(शरद) STart CHinta : (Digitalis, Liquorice, Picrorrhiza, Senna, Aloes, Rhubarb, Dioscorea, Strophanthus, Chiraita)

22/03/2024

Alkaloids Tricks to Remember ;ROSE HAVE No Colour But Inside Cinn Blue Violet (Rauwolfia,Opium,Stramonium,Ergot, Hyoscyamus, Ashwagandha, Vinca, Ephedra, Nux-vomica, Coca, Belladona, Ipecacuanha,Cinchona,Berberis,Vasaka)