10/06/2025
It's the science that sets us apart from other products:
Dr. Martin Pall, PhD and Dr. Stephen Levine, PhD from Washington State University had their research findings published in a journal called Acta Physiologica Sinica titled, "Nrf2, a master regulator of detoxification and also antioxidant, antiinflammatory and other cytoprotective mechanisms, is raised by health promoting factors"
In this peer-reviewed publication, Drs. Pall and Levine proclaimed:
💥"We may be on the verge of a new literature on health effects of Nrf2 which may well become the most extraordinary therapeutic and most extraordinary preventive breakthrough in the history of medicine."
A BOLD and REVOLUTIONARY statement, but a TRUE one.
Would you like to know what else these scientists stated about Nrf2?
I am not making claims of cure, treatment, mitigation, or prevention. I am simply posting EXCERPTS from Drs. Paul and Levine's research :
💥Raising Nrf2 has been found to PREVENT and/or TREAT a large number of CHRONIC INFLAMMATORY diseases in animal models and/or humans.
💥Nrf2 has been shown more recently to have many cytoprotective effects that go far beyond antioxidant effects. These include activation of over two dozen genes involved in DETOXIFICATION of a wide variety of xenobiotic toxicants.
💥Nrf2 and the system that regulates Nrf2 LOWER INFLAMMATORY responses, IMPROVE MITOCHONDRIAL FUNCTION and STIMULATE AUTOPHAGY, a process by which both toxic protein aggregates and dysfunctional organelles can be degraded. Three of these effects, the LOWERING OXIDATIVE STRESS, INFLAMMATORY BIOCHEMISTRY and IMPROVING MITOCHONDRIAL FUNCTION should LOWER the PATHOPHYSIOLOGY involved in dozens of CHRONIC INFLAMMATORY DISEASES and so may be expected to be useful in the prevention or treatment of many common chronic diseases.
💥The important DETOXIFICATION roles of Nrf2 mean that raising Nrf2 activity is likely to be of particular importance to the HUNDREDS OF MILLIONS OF PEOPLE around the globe who are regularly exposed to toxic chemicals that cause diseases characterized by oxidative stress, inflammation and mitochondrial dysfunction, diseases which include most of the chronic diseases of 21st century life.
💥The components of Protandim were shown in cell culture to act synergistically in raising Nrf2 responses, probably due to the role of multiple signaling pathways in their actions in raising Nrf2.
💥The STUNNING apparent BREADTH of the EFFECTS of Nrf2 on diverse diseases produces a challenge for medicine. Medicine has historically focused mainly on the ways in which these various diseases differ from one another, as a way of understanding their differences. However it is possible that these DIVERSE CHRONIC INFLAMMATORY DISEASES ALL have a SIMILAR UNDERLYING MECHANISM and differ from one another primarily in their localization in the body, with the differences in localization being responsible for any differences in their etiologies.
******************
The scientists then list "diseases where raising Nrf2 is reported to be useful in prevention and/or treatment in animal models and/or humans".
Cardiovascular diseases including atherosclerosis, ischemic cardiovascular disease, vascular
endothelial dysfunction, and heart failure
Neurodegenerative diseases including Alzheimer’s, Parkinson’s, ALS, Huntington’s diseases
Cancer (prevention)
Chronic kidney diseases
Metabolic diseases: Type 2 diabetes; metabolic syndrome; obesity
Several types of toxic liver disease
Chronic lung diseases including emphysema, asthma, and pulmonary fibrosis
Sepsis
Autoimmune diseases
Inflammatory bowel disease
HIV/AIDS
Multiple sclerosis
Epilepsy
Hemoglobinopathies including sickle cell disease and β-thalassemia
Malaria
Spinal cord injury
Traumatic brain injury
Altitude sickness
The three classic Psychiatric diseases, major Depression, Schizophrenia and Bipolar disorder
Gastric ulcers
Glaucoma
Age-related macular degeneration
Cataract
Pathophysiological responses to herpes activation
Benign prostatic hyperplasia"
And I(Janine B) am going to add MTHFR gene mutation to that list !
