16/03/2026
NAD+ Supplements ❤️
Yesterday I wrote that injectable glutathione is my favorite supplement. Today I want to talk about injectable NAD, which is my second favorite.
Injectable glutathione gives me a very clean and smooth energy that lasts for hours. It is the kind of energy that both calms and energizes at the same time. It puts me in the perfect mood to take my white Maserati Grecale GT SUV to work and continue expanding manual osteopathy and naprapathy in the United States. 😀
Injectable NAD, on the other hand, gives a completely different type of energy. It is raw power like you have never experienced. The kind that makes you say YOLO and take the red Maserati GranTurismo Sport out for a topless drive. That car has a Ferrari engine and even when using only half of its power it feels incredibly fast. I have driven many cars in my life, but this is the only one where I have not yet dared to push the full power. 😀
One thing I admire so much about the United States is its healthcare system. Personal liberty is extremely important there, and people are allowed to have far more control over their own health compared to many other countries where governments impose heavy restrictions. In the U.S. it is much easier to access advanced testing, specialists, and innovative therapies. Recently, for example, Robert F. Kennedy Jr., the US Secretary of Health & Human Services lifted restrictions on several peptides that may have significant health benefits. Many other countries eventually follow the U.S., but often years later. If someone is interested in advanced anti-aging or cutting-edge therapies, the United States is often the best place to access them. ❤️
Currently NAD+ is one of the most popular anti-aging molecules used in the United States. NAD+ (nicotinamide adenine dinucleotide) is a critical molecule involved in mitochondrial energy production, DNA repair, and cellular aging. Levels naturally decline with age, stress, metabolic disease, and poor lifestyle habits.
There are several ways to increase NAD naturally. Exercise is one of the most powerful, especially aerobic exercise and high-intensity training. Intermittent fasting and mild calorie restriction can also increase NAD levels. Good sleep and proper circadian rhythm are important as well.
Certain foods support NAD production, including turkey, chicken, beef, liver, salmon, mushrooms, peanuts, avocados, and green peas. Polyphenols that activate NAD-related pathways may also help, such as resveratrol from red grapes, quercetin from apples and onions, catechins from green tea, and curcumin from turmeric. Sauna use, cold showers, maintaining healthy body weight, improving insulin sensitivity, lowering chronic inflammation, reducing sugar intake, and ensuring adequate intake of vitamin B3 (niacin), vitamin B2 (riboflavin), vitamin B6, magnesium, and zinc all support NAD metabolism.
There are also oral supplements such as NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide) that help the body increase NAD production. These supplements are relatively expensive, usually around $100 per month. Many people also take glutathione, CoQ10, and B-complex vitamins together with them to support mitochondrial function and NAD production.
The gold standard, however, is subcutaneous NAD injection. This is more expensive, typically ranging from about US$250 to US$700 per month. The injection can be done one to seven times per week, with three times per week being the most common schedule, followed by a break of two to four weeks.
NAD supports mitochondrial energy production and activates longevity pathways involved in DNA repair, metabolic regulation, and cellular stress resistance. It can improve insulin sensitivity, glucose metabolism, and fat oxidation. NAD may also support brain health and has been studied for possible neuroprotective effects in conditions such as Alzheimer’s disease, Parkinson’s disease, and stroke recovery. It may also improve muscle function, exercise capacity, cardiovascular health, and certain aspects of biological aging.
Unlike glutathione, which is generally considered very safe, the long-term effects of high-dose NAD therapy are still not fully known. It is also quite expensive. When combined with other supporting supplements, the monthly cost can easily reach between US$500 and US$1000. However, many wealthy individuals in the United States are using NAD therapies and the results can be impressive. It is not uncommon to see people in their 60s and 70s who look and function like people in their 40s or 50s.
Personally, I enjoy both glutathione and NAD injections. However, I like the feeling of glutathione slightly more. I used to take them on the same days, but the powerful stimulation from NAD tends to overpower the smooth energy of glutathione. Now on the two days per week that I take glutathione, I do not take NAD so that I can fully enjoy that clean and calm energy.
Together these supplements have improved many of my blood markers, including liver enzymes and several other health indicators.
If someone can only choose one, I would recommend glutathione. But if a person understands the risks and can afford it, using both can be a very powerful combination. With both bigger is not better. Slow dose is my preference.
Have a great day and God bless.
Dr. Shawn Pourgol, MBA, DC, DO, DN, PhD
Osteopath, Naprapath, Chiropractor & Founder of:
National Academy of Osteopathy (Canada, USA)
National University of Medical Sciences (USA, Spain, Panama)
Osteopathy Chronic Pain Clinics of Canada (380 clinics in 34 countries)
Florida Naprapathic Association
World Osteopathy Day
