𝕂𝔸𝕐𝔸 𝔽𝔼ℕ𝕌𝔸

10/01/2026

**pCAN

09/01/2026

05/01/2026

Congrats

02/01/2026

Toilet paper relies on short fibers and constant harvesting making it a perfect fit for fast-growing plants like h**p. From the paper itself to the cardboard tube, h**p pulp could and should replace tree-based materials in products like this.

28/12/2025

Des champignons pour traiter les TOC ? 🍄 Intrigant !

28/12/2025

CBD et THC : une lueur d'espoir contre le cancer ?

27/12/2025

27/12/2025

27/12/2025

27/12/2025

Vascular tone is one of those quiet functions that keeps us alive without asking for attention. It is the constant tightening and relaxing of blood vessels that regulates blood pressure, tissue oxygenation, and nutrient delivery. When that tone is lost or becomes rigid, everything downstream suffers. CBD and CBGa support this system not by forcing vessels open or shut, but by helping the body restore intelligent control through the ECS, our Master Regulator.

CBD has been the most studied in this area, and the data is clear. It supports healthy vasorelaxation through endothelial signaling, nitric oxide pathways, and calcium channel modulation. In simple terms, CBD helps blood vessels respond appropriately to demand rather than remaining locked in a stressed state. This was demonstrated in the study “Cannabidiol, a non-psychoactive constituent of cannabis, causes endothelium-dependent vasorelaxation in human mesenteric arteries,” published in 2005. The researchers showed that CBD directly relaxed human arteries via endothelial mechanisms, confirming its role in maintaining proper vascular tone.

CBGa works earlier in the biological chain. As the precursor to many cannabinoids, CBGa behaves more like a regulator than an actuator. It interacts with ion channels, inflammatory signaling, and lipid metabolism that influence how blood vessels behave under stress. Rather than directly pushing dilation, CBGa helps calm the inflammatory and oxidative signals that cause vessels to stiffen, constrict, or lose responsiveness over time. This is especially important in chronic conditions where vascular tone becomes dysfunctional due to long-term stress, inflammation, or metabolic imbalance.

CBG, which forms from CBGa, has also been shown to influence adrenergic and TRP channel activity involved in vascular control. In the study “Cannabigerol is a novel, well-characterized inhibitor of alpha2-adrenoceptor-mediated responses,” published in 2010, researchers demonstrated that CBG modulates receptor-driven vascular responses. CBGa feeds into this pathway upstream, supporting balance before dysfunction takes hold.

Together, CBD and CBGa do not act like blood pressure drugs. They do not override physiology. They support communication, responsiveness, and resilience inside the vascular system. Healthy tone is not about being relaxed all the time; it is about being able to respond. When vessels can listen again, circulation improves, pressure stabilizes, and the body does what it was designed to do: regulate itself.

-Mike Robinson, The Researcher OG