29/11/2025
The 5 Stages of Kidney Disease:
Chronic kidney disease (CKD) is a progressive condition categorized into five stages, each defined by how efficiently the kidneys are filtering waste, measured through a blood test called eGFR (estimated glomerular filtration rate).
In the early stages (1–3), kidney function remains relatively intact, but signs of damage—like protein in the urine—may begin to emerge. Most people in these stages may not feel symptoms, though Stage 3 can bring fatigue, swelling, or high blood pressure as waste begins to build up in the body.
As CKD advances to Stages 4 and 5, kidney function becomes severely impaired.
In Stage 4 (eGFR 15–29), serious complications like bone disease and heart issues may occur. By Stage 5 (eGFR below 15), kidney failure sets in, requiring dialysis or a kidney transplant for survival.
Monitoring both eGFR and urine albumin-to-creatinine ratio (uACR) helps doctors determine not only the stage of CKD, but also the risk of progression and related health complications.
Early detection and intervention can slow the disease and preserve kidney function for as long as possible.
Source: Reviewed by Lakhani, S. (2025, July 21). Stages of chronic kidney disease (CKD). National Kidney Foundation.