
22/09/2022
Loperamide is an antimotility agent. It is a drug treatment for diarrhea. Antimotility agents are not recommended for use in children as trial results appear contradictory and any benefits are small with unacceptable levels of side effects observed.
Loperamide is relatively free of CNS(central nervous system) effects at therapeutic doses, although CNS depression may be seen in overdose, particularly in children.
Reference:
Walker, R. & Whittlesea, C. (Eds.) (2012). Clinical Pharmacy and Therapeutics. Churchill Livingstone.