16/07/2025
Dr. Alan Beer was a trailblazer in the field of reproductive immunology. His work laid the foundation for Lymphocyte Immunotherapy (LIT), a treatment that helps women with unexplained infertility, recurrent pregnancy loss, or repeated IVF failure by addressing potential immune-related causes. Dr. Beer’s approach has helped countless couples build families when traditional fertility treatments fell short.
LIT (Lymphocyte Immunotherapy or Leukocyte Immunotherapy) is a type of immunotherapy used to support pregnancy by modulating the maternal immune response. It is primarily used in cases of recurrent pregnancy loss (RPL) or implantation failure where immune factors may be involved.
Purpose of LIT
LIT aims to help the maternal immune system develop tolerance to the paternal antigens present in the embryo, reducing the risk of immune-related pregnancy complications.
How LIT Works
Lymphocyte Collection – White blood cells (lymphocytes) are collected from the male partner or a donor.
Processing and Injection – These lymphocytes are prepared and injected into the female partner’s skin or bloodstream.
Immune Modulation – The woman’s immune system recognizes the paternal antigens and develops a regulatory response, promoting embryo implantation and a sustained pregnancy.
Conditions Treated with LIT
Recurrent Pregnancy Loss (RPL) – When immune rejection is suspected as a contributing factor.
Unexplained Infertility – Particularly in cases where immune dysfunction may be involved.
Repeated IVF Implantation Failure – For individuals who have undergone multiple unsuccessful embryo transfers.
LIT is part of a broader approach to immunological fertility treatments, helping to enhance maternal immune tolerance and improve pregnancy outcomes.
