29/12/2020
Early next year, dermatologists could have an exciting new acne drug to add to their arsenal of treatment options. Winlevi is a first-of-its-kind topical cream that was officially approved at the end of August by the United States Food and Drug Administration (FDA) for use in patients 12 years and older. The acne treatment is expected to be available at the beginning of 2021.
"Other commonly used acne medications include topical antibiotics and topical retinoids, but Winlevi, also called Clascoterone Cream 1%, is different in that it is the only topical medication that targets the androgen receptors in the skin," says board-certified dermatologist and founder of Eternal Dermatology, Ife Rodney. "The result is less sebum production and oil buildup."
Androgens are hormones that are responsible for driving sebum production and inflammation — both of which are leading causes of acne. According to a press release from Cassiopea, the pharmaceutical company behind the development of Winlevi, the drug's active ingredient, clascoterone, "acts by limiting the effects of these hormones," which thereby leads to fewer breakouts.
In clinical trials conducted by Cassiopea, Winlevi demonstrated a reduction in acne lesions and was well-tolerated when applied to the skin twice a day. The most common side effect, which occurred in 7 to 12 percent of patients, was mild erythema — aka reddening of the skin. (Other potential side effects include burning, itching, and peeling.)
"As with other topical acne medications, [Winlevi] may cause redness, dryness, and irritation of the skin," confirms Rodney. "You should also be careful to not apply it to very large areas of the skin or for long periods of time, as this may increase the risk of internal side effects, like hormonal imbalance."
New York City-based board-certified dermatologist Shari Marchbein tells Allure she's excited to try Winlevi and add it to her treatment armamentarium. That being said, she doesn't believe it'll be a complete cure-all.
"I feel it will work best as an additional treatment option in a comprehensive routine but, not necessarily as monotherapy," she says. "I also do not feel this will substitute for oral medications that mediate hormones, like Spironolactone."
Needless to say, this is definitely promising news for skin-care experts and those with acne alike.
More on acne:
How to Identify and Find the Best Treatment for Every Kind of Acne
Stress Acne Is Real — and Why You May Be Breaking Out Right Now
The Best Acne Kits for Clearing Up Breakouts, According to Dermatologists
Now check out 100 years of acne treatments:
Watch Now: Allure Video.
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Gallery: The 9 Best Shampoos for Scalp Psoriasis Recommended By Dermatologists (Allure)
Slide 1 of 10: Here's the lowdown on how to subscribe to Allure's print edition for more beauty routines, recommendations, and features. It's pretty safe to say that scalp problems of any nature (itchiness, flaking, and the like), are highly annoying to anyone suffering from them. But scalp psoriasis — a common condition characterized by thick, red scaly patches of skin that can cover the entire scalp and be chronic — is arguably the most painful and inconvenient of them all. Scalp psoriasis treatment often comes in the form of oils, steroid solutions, and even ointments, but basic care for it starts in the shower with the shampoo you use. Those battling scalp psoriasis want to aim for a formula that simultaneously sloughs away flakes as it soothes irritation. New York City-based dermatologist and founder of Smarter Skin Dermatology, Sejal Shah, says that you should look for a shampoo comprised of ingredients such as salicylic acid and coal tar, the latter of which is a dark liquid that's a by-product of the production of coke and coal gas from coal and is used in medications to treat psoriasis and seborrheic dermatitis. It may sound scary, but dermatologists say it significantly helps to slow down the rapid growth of skin cells while reducing inflammation. Ahead, find Shah's favorite shampoo picks for scalp psoriasis, as well as other expert recommendations. All products featured on Allure are independently selected by our editors. However, when you buy something through our retail links, we may earn an affiliate commission.
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1/10 SLIDES © Getty Images
Here's the lowdown on how to subscribe to Allure's print edition for more beauty routines, recommendations, and features.
It's pretty safe to say that scalp problems of any nature (itchiness, flaking, and the like), are highly annoying to anyone suffering from them. But scalp psoriasis — a common condition characterized by thick, red scaly patches of skin that can cover the entire scalp and be chronic — is arguably the most painful and inconvenient of them all. Scalp psoriasis treatment often comes in the form of oils, steroid solutions, and even ointments, but basic care for it starts in the shower with the shampoo you use.
Those battling scalp psoriasis want to aim for a formula that simultaneously sloughs away flakes as it soothes irritation. New York City-based dermatologist and founder of Smarter Skin Dermatology, Sejal Shah, says that you should look for a shampoo comprised of ingredients such as salicylic acid and coal tar, the latter of which is a dark liquid that's a by-product of the production of coke and coal gas from coal and is used in medications to treat psoriasis and seborrheic dermatitis. It may sound scary, but dermatologists say it significantly helps to slow down the rapid growth of skin cells while reducing inflammation. Ahead, find Shah's favorite shampoo picks for scalp psoriasis, as well as other expert recommendations.
All products featured on Allure are independently selected by our editors. However, when you buy something through our retail links, we may earn an affiliate commission.
Microsoft may earn an Affiliate Commission if you purchase something through recommended links in this article.
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