Doctor of Pharmacy

28/09/2025

Pharmaceutical Questions and answers for interviews.

What is Production?
All the activities involved in the manufacturing of a pharmaceutical product starting from receipt of raw materials to the completion of a finished product means, from Raw material Receipt to Finished product dispatch.

It contains the handling of manpower and recording of the manufacturing and the packing activity

What is the Batch Manufacturing Record(BMR)

BMR is a Document that provides a history of a batch that means how a product is manufactured step by step following written procedures.

It contains signs of qualified persons and operators involved in manufacturing.
What is Batch packaging Record (BPR)

Batch packaging record or BPR is the document that provides a history of batch packaging and in-process checks of Packaging.

Define Tablet
Tablet is a solid dosage form prepared by a combination of API and Excipients by application of pressure.

What is API
API stands for Active pharmaceutical ingredient.

API is a substance that gives pharmacological effects.

What are Excipients?
Inert materials which do not give any pharmacological effect.

Classification of Excipients for Solid Dosage form.

Diluents
Binders
Disintegrants
Glidents
Lubricants
Colourants
Flavours

Tests for Tablet
Weight variation
Thickness...

Read the complete article in the following

Read most commonly asked interview questions for pharma job especially related to the production department.

27/09/2025

Basic learning topics for QA professionals

QA interview questions
https://www.pharmainform.com/2022/10/quality-assurance-interview-questions.html

FDA form 583 and warning letter
https://www.pharmainform.com/2024/04/fda-form-483-and-warning-letter.html

Difference between QA and QC
https://www.pharmainform.com/2023/06/difference-between-qa-qc.html

FIFO,FEFO and LIFO
https://www.pharmainform.com/2024/01/fifo-fefo-lifo.html

What is a URS
https://www.pharmainform.com/2023/06/urs-user-requirement-specifications.html

Process validation
https://www.pharmainform.com/2021/05/validationprocess-validation.html

Qualification in pharma
https://www.pharmainform.com/2021/01/qualificationiqdqoqpqursfatsat.html

Difference between validation and calibration
https://www.pharmainform.com/2021/01/difference-between-validation-and-calibration.html

27/09/2025

A pharmacist wants to compress 100,000 tablets at 240 mg weight.According to the BP it should be compressed within which of the following weight ranges?

a)230 mg -246 mg
b)216 mg -264 mg
c)228 mg -252 mg
d)222 mg -258 mg

Read Answer in following
https://www.pharmainform.com/2021/01/weight-variation-during-tablet-compression.html

26/09/2025

👉Are You Among Those 90 % Pharmacists Who Are Not Aware Of This Concept?
👉Did You Ever Think That Blender Capacity In Kilograms Is a Wrong Concept?
👉Why Can't We Mix 100 kgs Of Metformin & 100 Kilograms of Aerosil In The Same Blender?
👉The Capacity Calculation Process Is Not Commonly Implemented?
👇👇👇👇👇
Do Read To Change Your Concept.

Capacity of blenders is taken in litres not in kilograms because if we take it in Kgs it does not remain same for denser and lighter products

26/09/2025

👉Reconciliation VS Pharmacist?
👉What is Product Reconciliation?
👉Learn Basic Product Reconciliation Calculations?
👉How to Calculate Yield?
👉What is Line Loss?
👉How to Calculate Line Loss?
👉Practical Examples Of Product Reconciliation?

Read all these in following
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Product reconciliation is a process that is used to calculate and monitor the line loss or yield of a product that is under manufacturing. Calculation of yield or line loss ... Read more

25/09/2025

Empty hard gelatin shells normally have _______ moisture.

a)7-10%
b)10-12%
c)13-16%
d)17-20%

Read answer in following
https://www.pharmainform.com/2021/03/capsuleshard-gelatin-capsulessoft-gelatin-capsules.html

25/09/2025

👉What Is Cleaning Validation?
👉Principle Of Cleaning Validation?
👉Worst Case Scenario?
👉FDA Guidelines?
👉Importance Of Cleaning Validation?
👉Steps Of Cleaning Validation?
👉Sampling Methods?
👉Acceptance Criteria?
👉What Is MACO?
👉What Is NOEL?

Read All In Following

Cleaning validation is a process that is gaining more & more attention day by day in the pharma industries. The reason behind its highest demand is that most of the ... Read more

24/09/2025

Multi-Tip Tooling For Compression Machine

Tablet compression machine tooling consists of upper punches, lower punches & dies. The number of punches & dies varies depending on the type & model of tablet compression machines. The compression machine tooling is used to convert the powder or granules into tablets. The size, shape, embossing & weight of tablets depend on the tooling used for the compression machine.

The conventional tooling used in pharma is known as single-tip tooling, as the punch consists of only one tip to compress the tablet & die has only one cavity/hole to fill the powder or granules for compression.

The new emerging concept for tablet compression machine tooling is multiple tooling. There are many benefits & constraints associated with multi-tip tooling, which will be discussed in this article, but first, we will learn what multi-tip tooling is.

Multi Tip Tooling
As the name indicates, in multi-tip tooling, each punch has more than one tip to compress the tablets & each die has more than one cavity to fill the powder or granules. The number of die cavities will be the same as the number of tips & number of tips may be 2,3,4,5, or more, depending on the punch size & tablet dimensions.

Why Use Multi-tip Tooling?
The main aim of replacing single-tip tooling with multi-tip tooling is to enhance the output or productivity of the compression machine, but how? Let’s try to understand with a practical example

For Single-tip Tooling
Suppose we have a double-feed tablet compression machine having...

Read the complete article in the following

In multi-tip tooling, each punch has more than one tip to compress tablets & each die has more than one cavity to fill the powder or granules

24/09/2025

👉Why we Use 70% IPA for Disinfection?
👉Why 100% IPA is not effective to kill microbes?
👉How to prepare 70% IPA?
👉Mechanism Of Killing Microbes?
👉Role of water along with IPA for disinfection?

Read all these in following
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100 % IPA does not kill microbes instead it coagulates the outer proteins rapidly which prevents further pe*******on of IPA

23/09/2025

👉What is Line?
👉What Clearance?
👉What is Type A,B & C Cleaning?
👉What to do when move from 500mg to 250mg?
👉What to do if Flavour of a product changes?
👉What to do if Color of a product changes?
👉Importance of Line Clearance?
👉Height of partition between two lines?

Read all these in following
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Line clearance is critical process performed in pharmaceuticals before the start-up of the Dispensing, manufacturing or packaging process.

22/09/2025

The tablet friability test is one of the most important tests performed for uncoated tablets in the pharmaceutical industry by using an apparatus known as the Roch friabilator.

If you want to learn details about the Roch friabilator then read the following article because in the current article, we will only discuss the formula used for the probability calculation or how we calculate tablet Friability.
Friability Formula

To calculate the friability of uncoated tablets we use the following formula,
W1-W2 ÷ W1 × 100

W1 is the initial weight of the tablets meaning the weight of tablets before the friability test is known as W1.

W2 is the weight of tablets after the friability.

How to calculate tablet Friability

Take the required number of uncoated tablets as per pharmacopoeial specifications.

Clean the tablets means remove powder particles attached to the outer surface of tablets with the help of a small brush.

Check the weight of these...

Read the complete article in the following
https://www.pharmainform.com/2024/10/how-to-calculate-friability-of-tablet.html

22/09/2025

A production pharmacist wants to manufacture 300,000 tablets of Amlodipine 5 mg.The assay of amlodipine is 98% calculate the amount of amlodipine required?Amlodipine is available in the form of amlodipine besylate.

a)1.50 kg
b)1.53 kg
c)2.047 kg
d)2.127 kg

Read Answer in following
https://www.pharmainform.com/2020/12/potency-or-assay-calculation-of-api.html