09/11/2025
Vs Albendazole For pregnant animals 👇
1. Early pregnancy is a sensitive period
👉During the first 1–6 weeks of pregnancy (depending on the species), the embryo is forming vital organs.
👉Many anthelmintic drugs (dewormers) can interfere with embryonic development or cause embryo death if given at this stage.
That’s why routine deworming is usually delayed until mid or late pregnancy, unless worms are causing serious health problems.
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💊 2. Why ivermectin can sometimes be used
Ivermectin has been shown in many studies (especially in cattle, sheep, and goats) to have a wide safety margin, even in early pregnancy, when given at recommended doses.
It does not easily cross the placenta in harmful amounts.
Therefore, it is considered safer than many other dewormers, such as albendazole, levamisole, or oxfendazole, which are known to cause embryo loss or deformities if used too early.
⚠️ 3. Still, use with caution
Even ivermectin should be avoided in very early pregnancy (first 2–4 weeks) unless necessary.
The general rule is:
> “Avoid all anthelmintics during the first trimester unless the animal’s health requires immediate treatment.”
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✅ Summary
Drug Type Early Pregnancy Use Reason
Ivermectin Usually safe Low risk to embryo
Albendazole / Fenbendazole / Levamisole Can cause embryo loss or defects
Closantel / Rafoxanide Toxic to early embryos