Dr. Manzar Ali Laparoscopic Surgeon at Multan

04/01/2026

پتے کی پتھری کیوں بنتی ہے اور اس سے کیسے بچا جا سکتا ہے۔
Why incidence of gallstones increasing in Pakistan 🇵🇰 🤔

02/01/2026

شوگر کے مریض سردیوں میں آگ یا ہیٹر سے پاؤں گرم نہ کریں 🙏

21/12/2025

A new study comparing bariatric surgery vs. GLP-1 medications found that surgical patients lost five times more weight after two years. Researchers say GLP-1s are helpful—but not a “magic bullet.”

Find out why surgery still delivers the biggest results in obesity treatment:
🔗 Read the full story here: https://www.anesthesiologynews.com/a/IjIBAA/f

19/12/2025

vs 🤔 💭
Good fats (unsaturated) improve heart health by lowering bad cholesterol (LDL), while bad fats (saturated, trans) raise LDL, increasing heart disease risk. Good fats are liquid at room temp (oils, avocado, nuts, fish); bad fats are solid (butter, red meat, processed foods). The key difference is their impact on cholesterol and inflammation, with unsaturated fats promoting health and saturated/trans fats causing harm when overconsumed.
Good Fats (Unsaturated)
Monounsaturated & Polyunsaturated Fats (MUFAs & PUFAs): Liquid at room temperature.
Benefits: Lower LDL ("bad") cholesterol, raise HDL ("good") cholesterol, reduce inflammation, support brain health, help absorb vitamins.
Sources: Olive oil, avocados, nuts (almonds, walnuts), seeds (flax, chia), fatty fish (salmon, mackerel).
Bad Fats (Saturated & Trans)
Saturated Fats: Solid at room temperature.
Trans Fats (Artificial): Solid or semi-solid at room temperature; largely banned due to extreme harm.
Benefits: None, they are harmful in excess.
Sources: Red meat, butter, cheese, fried foods, pastries, processed snacks, margarine (trans fats).
Harm: Increase LDL cholesterol, contribute to artery plaque, raise risk of heart disease, stroke, obesity.
How to Choose
Focus on: Monounsaturated (olive oil, avocado) and Polyunsaturated (omega-3s in fish, flax) fats.
Limit: Saturated fats (fatty meats, full-fat dairy).
Avoid: Artificial Trans Fats (fried/processed foods).

18/12/2025

For the SLEEVE HATERS: 830 SLEEVES with up to 14 years Follow Up
- 3️⃣ bariatric centers of excellence 🥇
- 🔟 year median follow up ✅
- %TWL = 29%
- 16% suboptimal response to surgery
- Weight Gain of >20% from nadir = 57.5%
- MAJOR ⬆️⬆️obesity related comorbidity resolution and LOW ⬇️⬇️ relapse rate.
- 🔟 % required revisional surgery 🤩🤩

I do NOT believe we should advertise sleeve as a bad operation or as the new band… apparently it is NOT!

09/12/2025

Obesity is a chronic inflammatory state. Fat tissue releases cytokines like TNF-a and IL-6 that disrupt insulin signaling, damage blood vessels and affect the liver, pancreas and even cognitive function.

This inflammatory environment explains why obesity increases the risk of diabetes, fatty liver, cardiovascular disease, sleep apnea and certain cancers.

Treating obesity reduces inflammation and restores metabolic balance.
Bariatric surgery significantly lowers inflammatory markers and improve metabolic function beyond weight loss alone.

Hypertension and Diabetes are the most common complications of obesity.

After metabolic and bariatric surgery, many patients see blood pressure and blood sugar normalize or require fewer medications.

Why? Reduced inflammation, improved insulin sensitivity, and better metabolic function all support cardiovascular health.

We encourage timely treatment of obesity to protect the heart and other vital organs.

Improving inflammation starts with addressing its source.

Regards 💐
Dr. Manzar Ali
Laparoscopic & Bariatric Surgeon
Professor & HOD Surgery MMDC, Multan
City Hospital Multan: 2.30 pm to 4.30 pm
Fatima Medical Centre 5:00pm to 7:00pm
Call / WhatsApp for Appointment
📲 +92 303 7300750

30/11/2025

Hunger isn't about discipline – it's a hormonal system.
In obesity, this system misfires: ghrelin rises too early, leptin stops signalling satiety, dopamine circuits weaken and GLP-1 levels fall.

This creates a hunger that feels stronger than your efforts, because it is.
Modern treatments focuses on correcting biology, not blaming behaviour.

When appetite signals normalize eating becomes manageable again.
If hunger feels louder than your habits, it deserves a medical evaluation.

You are welcome to consult regarding your hunger and weight management options with solution of obesity-related metabolic issues 👍

Regards 💐
Dr. Manzar Ali
Professor & HOD Surgery MMDC, Multan
General, Laparoscopic & Bariatric Surgeon
City Hospital Multan: 2:30 pm to 4.30 pm
Fatima Medical Centre 5:00 pm to 7:00 pm
Call/WhatsApp for Appointment 👇
📲 0303 7300750

27/11/2025

ہر کسی کو سمجھ لیتے ہیں یہ اپنے جیسا
اچھے لوگوں میں یہی بات بری ہوتی ہے

20/11/2025

11/11/2025

3 types of hunger explained "simply"

Hunger isn’t just about an empty stomach. Your brain receives signals from body composition, hormones, emotions, and even gut microbes. Here’s how the three major types work:

1️⃣ Homeostatic Hunger (Energy Balance Hunger)
This is your body’s “fuel gauge.” It rises and falls based on energy needs and metabolic signals.
What drives it: Ghrelin from the stomach stimulates hunger; leptin from fat cells and incretin hormones (GLP-1, PYY, CCK) reduce it.

What it does: Ensures your intake matches your energy needs for exercise, growth, and tissue repair.

🟢 Example: After a long run, homeostatic hunger pushes you to replace calories and glycogen.

2️⃣ Hedonic Hunger (Reward-Driven Hunger)
This is your “food pleasure” system. It’s triggered by sight, smell, habits, and emotions, not by actual energy needs.
What drives it: Brain reward circuits activated by highly palatable foods (sugar, fat, salt).

What it does: Encourages eating even when you’re not truly hungry. Weak satiety signals make it harder to stop.

🟢 Example: Craving dessert after dinner even though you’re full.

3️⃣ Microbiota-Driven Hunger (Gut Microbe Hunger)
Your gut bacteria also shape hunger signals by producing metabolites that influence hormones and the brain.

What drives it: Microbes generate compounds that mimic hunger or satiety signals, affect insulin, and modulate ghrelin, GLP-1, and PYY.

What it does: Links gut health to appetite regulation and metabolic control.

🟢 Example: Certain bacterial imbalances may increase cravings or weaken satiety, nudging overeating.

Fasano, A. (2025). The physiology of hunger. The New England Journal of Medicine, 392(4), 372–381.

30/10/2025

Inauguration of CT Scan services at Ibne Siena Hospital , Multan & MMDC. A great addition indeed 👍 Best Wishes 💐

26/10/2025

Always keep diathermy settings at low for fine and safe dissection. Gently handle tissues with respect. Look, hook and cook safely and carefully. Expect the unexpected and be ready to discover and deal accordingly.
Long OT list, Sunday, at Al-Kareem Medical Centre, Fatima Jinnah Town ,
Teaching & Learning is my passion 🙇‍♂️ hectic day 👍
I have dedicated my Sundays for my less affording patients 💐