14/11/2024
Let's understand 2 interesting FEATURES of ESTROGEN and it's CLINICAL SIGNIFICANCE in MENOPAUSE:
1. INSULIN and ESTROGEN are BEST FRIENDS:
- Estrogen ➡️ improves activity of BETA-CELLS of PANCREAS ➡️ improves insulin production and sensitivity.
- In MENOPAUSE ➡️ no estrogen ➡️ less beta-cell activity ➡️ INSULIN BECOMES SAD ➡️ less insulin production ➡️ risk of DIABETES!!
2. ESTROGEN and FAT DISTRIBUTION:
- Estrogen ➡️ decides where FAT is to be STORED in the body
- Estrogen ➡️ accumulates FAT in the HIPS and THIGH region.
- In MENOPAUSE ➡️ no ESTROGEN ➡️ FAT gets REDISTRIBUTED to VISCERAL AREA (ABDOMINAL AREA)
- Abdominal fat accumulation ➡️ high risk of insulin resistance ➡️ risk of metabolic syndrome, including diabetes!!
That's why it's said that the risk of metabolic syndrome or cardiovascular events increase once a female attains menopause!!
Dr Inayat Khan
