Advances in Clinical and Experimental Medicine

Advances in Clinical and Experimental Medicine 5-Year IF 2.0, IF 1.9, JCI (2024) 0.43, Scopus CiteScore 4.3, H-index 49 (SJR)
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📢1st Rare Disease Congress – Rare Diseases for Pediatricians and Family Physicians📢We cordially invite you to participat...
29/09/2025

📢1st Rare Disease Congress – Rare Diseases for Pediatricians and Family Physicians📢

We cordially invite you to participate in the 1st Rare Disease Congress - Rare Diseases for Pediatricians and Family Physicians, which will take place on November 21–22, 2025, at the Mercure Hotel in Wroclaw.

This is not a motto that has been defined: There is no disease whose incidence is so rare that it does not require our special attention.

Rare diseases pose a challenge to modern medicine, the healthcare system, and society as a whole. Although they are indeed rare, patients with rare diseases are numerous – in Poland, they may affect over 2.5–3 million people.

To date, nearly 8,000 conditions have been described that meet the definition of a rare disease (one person in 2,000 inhabitants). These diseases have a variety of symptoms, a progressive course, and often a poor prognosis. They encompass every field of medicine, so every doctor, nurse, physiotherapist, therapist, or other medical specialist undoubtedly encounters them in their practice. Early diagnosis and initiation of appropriate treatment are crucial.

Rare diseases, like all chronic diseases, require comprehensive and coordinated care. However, in medicine, pediatricians and family medicine physicians are closest to the patient with a rare disease. Therefore, to address the need to systematize and deepen knowledge about rare diseases, we invite you to the two-day First Congress of Rare Diseases, is organized by the Polish Society of Pediatric Endocrinology and Diabetology and the Polish Society of Congenital Metabolism, in cooperation with: the Polish Society of Human Genetics, the Polish Society of Pediatric Neurologists and the Polish Society of Family Medicine. The Congress will be a unique platform for exchanging knowledge, experiences, and the latest advancements in the field. The program includes thematic workshops and panel discussions. We believe that the opportunity for shared debate broadens diagnostic and therapeutic perspectives, building the potential and value of every physician.

This will also be an opportunity for our integration, which often creates new opportunities and opens doors in difficult clinical situations, improving the quality of life of patients suffering from rare diseases.

WE WARMLY INVITE YOU TO WROCLAW

MORE INFORMATION [IN POLISH]:

https://ptmr.info.pl/wydarzenia/i-kongres-chorob-rzadkich/

https://grupamedica.pl/wydarzenia/i-kongres-chorob-rzadkich-choroby-rzadkie-dla-pediatrow-i-lekarzy-rodzinnych-21-22-11-2025-hotel-mercure-wroclaw/

📢International Neuroscience Conference📢We are proud to serve as a patron of the International Neuroscience Conference (N...
29/09/2025

📢International Neuroscience Conference📢

We are proud to serve as a patron of the International Neuroscience Conference (NEURO-2025), which will take place on November 29–30, 2025, in Tbilisi, Georgia.

NEURO-2025 is the largest international neuroscience meeting in Georgia, bringing together leading experts, researchers, and clinicians from around the world to explore the latest advances in the field. The program will include keynote lectures, cutting-edge presentations, interactive discussions, and networking opportunities.

This year’s conference will focus on three key themes:

Decoding the Diseased Brain – neurochemical pathways, early markers, and precision diagnostics

Brain Circuitry and Cognition – from computational models to therapeutic innovation

Converging Neurotechnologies – restoring function and re-engineering brain health

NEURO-2025 aims to advance our understanding of neuroscience and neurosurgery, and to promote innovative solutions to current challenges in brain health.

More information is available at: https://neuroscience.edu.ge/

NEW REQUIREMENTS CONCERNING FIGURES IN ADV CLIN EXP MEDWe implemented new requirements regarding figures – they stem fro...
28/09/2025

NEW REQUIREMENTS CONCERNING FIGURES IN ADV CLIN EXP MED

We implemented new requirements regarding figures – they stem from stipulations issued by databases and digital archives in which our journal is indexed.

We accept up to 10 figures (2 figures in Research letters). Overtly complex figures will be divided into smaller ones and the number of figures will be counted again. A single figure can have no more than 6 panels (A–F). One panel means one chart – multiple small charts cannot form one panel.

All elements of each figure must be legible when viewed on an A4 page in a PDF file in full-screen mode, without zooming. Overtly complex figures with multiple charts/graphs combined into one panel cannot fulfill this requirement. Figures of low quality cannot be published, and consequently, papers with low-quality figures will not be published, even if accepted by peer reviewers.

Figures should be placed in separate files, not pasted into the main body of the text. Name your figure files with "Fig" and the figure number, e.g., Fig.1.tiff.

References to Figures should be placed according to the sequence of citing them in the manuscript. The text should include references to all figures.

Each figure should have a concise, self-explanatory caption describing accurately what the figure depicts. Captions for the figures should be placed at the end of the main body of the text. Do not embed the legend in the figure file. When applicable, be sure that both the figure captions and the figures themselves contain corresponding labels for multiple parts. Identify all elements found in the figure in the figure caption; and use boxes, circles, etc., as coordinate points in graphs. If any magnification is used in the photographs, indicate this by using scale bars within the figures themselves. All abbreviations used in a given table/figure should be explained below it or in the caption, even if a given abbreviation has already been explained in the text.

If Authors used in the work any figures, photographs, charts, tables, etc. which are not their work, and are protected by the copyright law, they shall be obliged to provide the Publisher with a written authorization to use such materials issued by the author’s economic rights holders. Identify previously published material by giving the original source in the form of a reference citation at the end of the figure caption.

OUR NEW TECHNICAL REQUIREMENTS:

https://advances.umw.edu.pl/source/Adv%20Clin%20Exp%20Med-figures-technical%20requirements.pdf

📰New category in our journal – Study Protocol articles 📰✅ Study Protocol articles provide a comprehensive overview of th...
28/09/2025

📰New category in our journal – Study Protocol articles 📰

✅ Study Protocol articles provide a comprehensive overview of the design of prospective research, aiming to facilitate the dissemination of ongoing studies and enhance transparency in clinical and biomedical research. These articles outline the hypothesis, rationale, methodology, and ethical considerations of the study, serving as a valuable resource for researchers and clinicians.

✅ We consider study protocols for proposed or ongoing prospective clinical research, provided that participant recruitment has not been completed at the time of submission. Protocols for retrospective studies, feasibility studies, or pilot studies are not eligible. Additionally, study protocols will not be considered if any articles reporting data from the study have already been published or are under review.

📌 Submission Guidelines 📌

• Study Protocol articles undergo peer review.
• The manuscript should not exceed 3,500 words.
• A maximum of 10 figures and/or tables may be included.
• The paper should follow a 5-part structure: Highlights, Introduction, Methodology, Discussion, Conclusion.
• The abstract should not exceed 300 words and follow a 4-part structure: Introduction, Methodology, Discussion, Conclusion.
• Formal ethical approval of an appropriate ethics committee is mandatory.
• For clinical studies, registration in a public clinical trial registry is mandatory prior to manuscript submission.
• Authors are strongly encouraged to follow the SPIRIT guidelines (SPIRIT Statement).

This structured approach ensures that Study Protocol articles contribute meaningfully to the research community while maintaining rigorous academic and ethical standards.

https://advances.umw.edu.pl/en/instructions-for-authors/

📢Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection onApplication of stem cell...
27/09/2025

📢Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on

Application of stem cells in human medicine – from basic science research to clinical trials 📢

Medicine in the twenty-first century is closely associated with stem cell research, based on advanced in vitro analyzes, the use of model animals, and their application in clinical trials. Experimental research requires understanding the physiological and morphological properties of stem cells and analyzing their ability to divide and differentiate into other cell types. The best-known stem cells are those derived from bone marrow and umbilical cord blood. However, in recent years, stem cells have been discovered in, for example, adipose tissue and Wharton jelly. Stem cells isolated from these tissues, once properly differentiated, are increasingly used for the treatment of bone and neurodegenerative diseases. In recent years, the number of therapies using stem cells has increased significantly. The ability of stem cells to differentiate makes them an increasingly common therapeutic tool in regenerative and reconstructive medicine.

Key words:

mesenchymal stem cells, embryonic stem cells, iPSCs, cancer stem cells, cell proliferation and differentiation, small extracellular vesicles, exosomes, omics, animal models, preclinical and clinical trials, regenerative medicine, reconstructive medicine

Articles submitted should be related to the topic of stem cells and their use in basic and clinical research. Topics may include:

• molecular research involving advanced genomic methods
• tissue and cell research
• studies on the morphological and physiological properties of stem cells
• studies on the proliferative and multidirectional differentiation capacity of stem cells
• studies on model animals
• use of stem cells in preclinical and clinical research
• therapies with stem cell
• stem cells in regenerative and reconstructive medicine
• stem cells in translational medicine

Review articles describing recent achievements in stem cell medicine, as well as original articles will be accepted.

MORE INFORMATION:

https://advances.umw.edu.pl/en/application-stem

📢1st Rare Disease Congress – Rare Diseases for Pediatricians and Family Physicians📢We cordially invite you to participat...
26/09/2025

📢1st Rare Disease Congress – Rare Diseases for Pediatricians and Family Physicians📢

We cordially invite you to participate in the 1st Rare Disease Congress – Rare Diseases for Pediatricians and Family Physicians, which will take place on November 21–22, 2025, at the Mercure Hotel in Wrocław.

Our journal took media patronage over this event.

This is not a motto that has been defined: There is no disease whose incidence is so rare that it does not require our special attention.

Rare diseases pose a challenge to modern medicine, the healthcare system, and society as a whole. Although they are indeed rare, patients with rare diseases are numerous – in Poland, they may affect over 2.5–3 million people.

To date, nearly 8,000 conditions have been described that meet the definition of a rare disease (one person in 2,000 inhabitants). These diseases have a variety of symptoms, a progressive course, and often a poor prognosis. They encompass every field of medicine, so every doctor, nurse, physiotherapist, therapist, or other medical specialist undoubtedly encounters them in their practice. Early diagnosis and initiation of appropriate treatment are crucial.

Rare diseases, like all chronic diseases, require comprehensive and coordinated care. However, in medicine, pediatricians and family medicine physicians are closest to the patient with a rare disease. Therefore, to address the need to systematize and deepen knowledge about rare diseases, we invite you to the two-day First Congress of Rare Diseases, is organized by the Polish Society of Pediatric Endocrinology and Diabetology and the Polish Society of Congenital Metabolism, in cooperation with: the Polish Society of Human Genetics, the Polish Pediatric Society, the Polish Society of Pediatric Neurologists and the Polish Society of Family Medicine.

The Congress will be a unique platform for exchanging knowledge, experiences, and the latest advancements in the field. The program includes thematic workshops and panel discussions. We believe that the opportunity for shared debate broadens diagnostic and therapeutic perspectives, building the potential and value of every physician.

This will also be an opportunity for our integration, which often creates new opportunities and opens doors in difficult clinical situations, improving the quality of life of patients suffering from rare diseases.

MORE INFORMATION [IN POLISH]:

https://ptmr.info.pl/wydarzenia/i-kongres-chorob-rzadkich/
https://grupamedica.pl/wydarzenia/i-kongres-chorob-rzadkich-choroby-rzadkie-dla-pediatrow-i-lekarzy-rodzinnych-21-22-11-2025-hotel-mercure-wroclaw/

💥We work with the best!💥Experts from Stanford University, under the supervision of Prof. John Ioannidis, in cooperation ...
25/09/2025

💥We work with the best!💥

Experts from Stanford University, under the supervision of Prof. John Ioannidis, in cooperation with Elsevier, prepared the 8th version of a publicly available database of top-cited scientists that provides standardized information on citations, h-index, co-authorship-adjusted hm-index, citations to papers in different authorship positions, and a composite indicator (c-score). This database includes a list of the top 2% most widely cited scientists in various disciplines. Separate data are shown for career-long and, separately, for single recent year impact. Metrics with and without self-citations and the ratio of citations to citing papers are given. The selection is based on the top 100,000 scientists by c-score (with and without self-citations) or a percentile rank of 2% or above in the sub-field. Career-long data are updated to end-of-2024 and single recent year data pertain to citations received during calendar year 2024. The selection is based on the top 100,000 scientists by c-score (with and without self-citations) or a percentile rank of 2% or above in the sub-field. This version is based on the August 1, 2025 snapshot from Scopus, updated to end of citation year 2024.

This list shows how many top researchers are in our Scientific Committee and among our section editors – 20! It’s clear proof that experienced and renowned specialists want to work with us and contribute to the development of Advances in Clinical and Experimental Medicine!

The congratulations go to: Sandra Maria Barbalho, Maria Magdalena Bujnowska-Fedak, Antonio Cano, Chong Chen, Breno Diniz, Chris Fox, Kinga Grzech-Leśniak, Donata Kurpas, Christopher S. Lee, Jerzy Leszek, Christos Lionis, Adam Matkowski, Monika Sawhney, James Sharman, Jamil Awad Shibli, Jacek Szepietowski, Robert Śmigiel, Masaru Tanaka, Izabella Uchmanowicz, and Ming Yi.

The database is available here:

https://elsevier.digitalcommonsdata.com/datasets/btchxktzyw/8


Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

🚀 Ahead of print🚀Diagnosis and management of traumatic injuries in pediatric patients secondary to dental local anesthes...
24/09/2025

🚀 Ahead of print🚀

Diagnosis and management of traumatic injuries in pediatric patients secondary to dental local anesthesia: A systematic review

Highlights

• Self-inflicted soft-tissue injuries after pediatric dental anesthesia are common, most often involving the lips, cheeks and tongue.
• These wounds can progress to infection, allergic reaction or neuropathy, so each must be considered in the clinical differential diagnosis.
• Rapid anesthetic reversal with intra-oral splints, phentolamine mesylate (OraVerse®) or photobiomodulation therapy shortens numbness time and lowers injury risk.
• Standardized anesthesia protocols and long-term, multicenter studies are essential to refine prevention, diagnosis and treatment of soft-tissue injuries in children.

https://advances.umw.edu.pl/en/ahead-of-print/204391/



Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

📢Meet the author of our latest editorial!📢Dr. Nasrollah Moradikor➡️READ THE EDITORIALNutrition & exercise for brain heal...
23/09/2025

📢Meet the author of our latest editorial!📢

Dr. Nasrollah Moradikor

➡️READ THE EDITORIAL

Nutrition & exercise for brain health: Enhancing cognitive function and neuroplasticity

https://advances.umw.edu.pl/en/ahead-of-print/208533/

➡️SHORT BIO

https://ojs.umw.edu.pl/files/acem/Moradikor-Biography%20%281%29.pdf

➡️MINI-INTERVIEW

1. Are there diets from specific world regions (apart from Mediterranean diet discussed in your paper) that are particularly beneficial for brain health?
Yes, besides the Mediterranean diet, several traditional diets around the world are linked to brain health. Nordic diets, rich in whole grains, fatty fish, fruits, and vegetables; Japanese and Okinawan diets, emphasizing fish, vegetables, soy, green tea, and fermented foods; and traditional Indian diets, including spices like turmeric and ginger, all provide antioxidants, omega-3 fatty acids, and anti-inflammatory compounds that protect cognitive function. These diets help support memory, attention, and overall brain health, slow brain aging, and, like the MIND diet, promote neuroplasticity while minimizing refined sugars and processed foods.

2. Why does high-intensity exercise has been shown to impair cognitive performance, in contrast to medium-intensity physical activity?
High-intensity exercise can sometimes impair cognitive performance because it puts the body under a lot of stress. During very intense activity, the body directs most of its blood and energy to the working muscles, which can reduce the oxygen and nutrients available to the brain, especially in areas like the prefrontal cortex that control memory, attention, and decision-making. At the same time, stress hormones like cortisol and adrenaline rise sharply, which can temporarily interfere with thinking and focus. High-intensity exercise can also cause metabolic strain, such as energy depletion and lactate buildup, which may affect brain function. In contrast, moderate-intensity exercise increases blood flow to the brain, supports the production of neurotrophic factors like BDNF, and improves mood and attention without overloading the brain, making it more effective for enhancing cognitive performance.

3. What are the lifestyle factors (especially diet and exercise habits) that could be improved among the general population in countries you know best (Georgia and Germany)?
In countries like Georgia and Germany, several lifestyle factors related to diet and exercise could be improved to better support brain health and overall well-being. In Georgia, traditional diets are often high in refined carbohydrates, saturated fats, and sugars, with limited intake of vegetables, fruits, and whole grains, and physical activity levels can be relatively low, especially in urban areas. Increasing consumption of antioxidant-rich foods, whole grains, healthy fats like those from fish or nuts, and reducing sugar and processed foods, along with encouraging regular moderate exercise, could enhance cognitive function and prevent chronic diseases. In Germany, although people generally have access to healthy foods, high consumption of processed meats, sugary snacks, and alcohol can be a concern, and sedentary behavior is increasing due to desk-based work and urban lifestyles. Promoting balanced diets rich in vegetables, fruits, and fish, reducing refined sugars and processed foods, and integrating daily physical activity, including aerobic and resistance exercises, could strengthen brain health, improve mood, and support healthy aging in the general population.

🚀Ahead of print🚀Assessment of the physical fitness status of patients with hematological malignancies qualified for hema...
22/09/2025

🚀Ahead of print🚀

Assessment of the physical fitness status of patients with hematological malignancies qualified for hematopoietic stem cell transplantation

Highlights

– Patients with hematological malignancies awaiting HSCT showed significantly reduced endurance and muscle strength compared to healthy adults, as measured by the 6MWT, TUG, and 30CST tests.

– Longer time from diagnosis to transplantation and multiple lines of systemic therapy were linked to poorer physical fitness outcomes, highlighting treatment-related deterioration.

– Prehabilitation tailored by physical fitness assessments may improve recovery and functional status after HSCT, reducing risks of sarcopenia, cachexia, and malnutrition.

– Findings underscore the importance of individualized rehabilitation programs for HSCT candidates, considering diagnosis type, therapy history, and timing to transplantation.

https://advances.umw.edu.pl/en/ahead-of-print/193825/


Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

📢 Our new manuscript withdrawal policy 📢✔️ Withdrawals initiated by authorsAuthors may withdraw their manuscript at any ...
21/09/2025

📢 Our new manuscript withdrawal policy 📢

✔️ Withdrawals initiated by authors
Authors may withdraw their manuscript at any stage of the editorial process. However, 2 conditions must be met for a withdrawal request to be processed:

– A clear and specific reason for withdrawal must be provided – both in the Editorial System and in the withdrawal statement.
– All authors must consent to the withdrawal. A statement signed by all authors should be scanned and submitted as a PDF file to the editorial office at [redakcja@umw.edu.pl] and/or uploaded to the Editorial System as an Additional File.

Until these conditions are fulfilled, the manuscript cannot be considered withdrawn.

Please note that if you intend to resubmit the manuscript, it is advisable to address necessary corrections during the initial verification or peer-review process rather than withdrawing the submission. A withdrawn and resubmitted manuscript is assessed as an entirely new submission – the previous (withdrawn) submission is not taken into consideration; in consequence, it prolongs the whole assessment process.

✔️ Withdrawals initiated by the editorial office
A manuscript will be withdrawn by the editorial office if:

– After acceptance, evidence for scientific misconduct is found
– Authors fail to sign the license agreement form within 30 days after acceptance
– Authors fail to pay the article processing charge (APC) within 30 days after acceptance
– Authors repeatedly fail to correct the galley proof or cease communication with the editorial office in this regard for more than 30 days.

✔️ Refund policy (withdrawals after the APC has already been paid)
Adv Clin Exp Med does not refund the APC once it has been paid. This policy applies in the following cases:
– When authors withdraw a manuscript after acceptance and payment of the APC (but before publication), regardless of the reason for withdrawal.
– When the manuscript is withdrawn by the editors due to the authors' failure to adequately correct errors or an attempt to change the authorship after acceptance (which violates our policy).
– When articles are retracted after publication due to author error or misconduct.
The APC is not a publication fee but an article-processing charge—it covers the costs of peer review, statistical review, editing, and typesetting. Since the majority of this work is completed before the APC is paid, refunds cannot be issued.
In exceptional cases, authors may appeal to the Editor-in-Chief, whose decision is final.

✔️ Withdrawal after acceptance due to funding limitations
We ask that authors submit papers to our journal only if they have funding. Before submitting, please make sure that you have the necessary funds to pay the APC in case of acceptance.
https://advances.umw.edu.pl/en/article-processing-charges/
Please note that our journal offers neither APC waivers nor discounts, including discounts for researchers from lower-income countries and countries against which international sanctions have been imposed.

✔️ Ethical considerations concerning withdrawals
Before you withdraw a paper, please consider that the editor and reviewers have likely already invested significant time reviewing your manuscript. The further along in the paper's peer-review process, the greater the ethical concern with withdrawing a manuscript, given that a considerable amount of time has been spent on the paper by reviewers, editors, and editorial assistants. Please let us know before withdrawing if there is anything we can do to avoid the withdrawal. We are happy to work with authors to remove any perceived barriers to publishing.
Please note that it is unethical and considered violating scientific norms (i.e., poor scientific practice bordering on scientific misconduct) to submit a paper still under consideration at a journal A to a different journal B. If you have already created a duplicate submission, please withdraw your paper from the other journal immediately and only submit it after receiving confirmation that your withdrawal request has been successfully processed. Otherwise, according to international best practices on publication ethics, a withdrawal may violate the research community's norms and may have negative consequences for the authors.

✔️ Withdrawing a published paper
Withdrawal is possible during the initial verification process, from the peer-review process or after acceptance, before publication. Withdrawing a paper after publication is called a retraction, please see https://advances.umw.edu.pl/en/appeals-complaints-corrections-retractions-commentaries for retraction policies.

📢Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on Advances in Cardiovascu...
20/09/2025

📢Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on Advances in Cardiovascular Care 📢

This Special Issue of the Advances in Clinical and Experimental Medicine will provide focused, comprehensive coverage of important clinical topics in cardiology. The issue will address selected clinical problems or conditions, including their pathophysiology, invasive and noninvasive diagnosis, drug therapy, surgical management, and rehabilitation.

This Special Issue aims to provide researchers with an opportunity to publish original research, meta-analyses and review articles related to recent advances in the cardiovascular field, with a particular focus on holistic and personalized management of patients with CVD.

Topic and format
Advances in Clinical and Experimental Medicine is therefore seeking original papers for a Special Collection focused on cardiovascular care.

MORE INFORMATION:

https://advances.umw.edu.pl/en/call-for-submissions-of-an-expression-of-interest-for-an-adv-clin-exp-med-special-collection-on-advances-in-cardiovascular-care


Izabella Uchmanowicz
Dr hab. Michał Czapla
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

Adres

Karola Marcinkowskiego 2-6
Wroclaw
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