27/07/2025
The power of 🥦
A natural molecule may soon revolutionize dental care.
Scientists have discovered that 3,3′-Diindolylmethane (DIM)—a compound found in cruciferous vegetables like broccoli—can eliminate up to 90% of the biofilm produced by Streptococcus mutans, the main bacteria behind dental plaque and cavities. This biofilm forms a sticky layer on teeth, leading to enamel erosion and tooth decay.
In lab studies, researchers from Ben-Gurion University, Sichuan University, and the National University of Singapore found that DIM effectively disrupts these biofilms without toxic side effects. This opens the door to a future where DIM could be added to toothpastes and mouthwashes to offer powerful, natural protection against cavities.
Even more intriguing? DIM has shown anti-cancer properties in previous research, suggesting its benefits may go beyond dental hygiene.
The findings were published in the journal Antibiotics, and scientists say this discovery could drastically improve how we prevent tooth decay—especially for populations with limited access to dental care.
If future studies confirm these effects in humans, DIM might just be the next big thing in oral health—transforming daily brushing into a science-backed shield against cavities.
Follow Science Sphere for regular scientific updates
RESEARCH PAPER 📄
Yifat Baruch et al, "3,3′-Diindolylmethane (DIM): A Potential Therapeutic Agent against Cariogenic Streptococcus mutans Biofilm", Antibiotics (2023)
