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17/11/2025

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05/11/2025

In a remarkable discovery, scientists have found that the brain can influence the gut microbiome in as little as two hours. Using mice models, researchers observed that brain signals rapidly altered the composition of gut bacteria revealing that communication between the brain and gut is not only mutual but astonishingly fast.

For years, we’ve known that gut microbes affect mood, immunity, and even cognition. But this study flips the script, showing that the brain can send signals that actively reshape the gut ecosystem. The finding highlights a dynamic, two-way relationship where stress, emotions, or brain activity can directly alter gut health.

This breakthrough opens exciting possibilities for future therapies. By understanding the pathways through which the brain communicates with gut microbes, scientists may develop treatments for digestive disorders, immune dysfunction, and even mental health conditions by targeting the mind itself.

Credit: Source — Nature Communications (2025), study on neural control of gut microbiome dynamics.

05/11/2025

🦷🔬 Scientists in Japan have created a drug that lets humans regrow lost teeth naturally!

The medication, created by researchers led by Dr. Katsu Takahashi at the Medical Research Institute Kitano Hospital, works by blocking a protein called USAG-1 that normally suppresses tooth growth.

In mouse trials, this inhibition successfully triggered the growth of brand-new teeth, and the team is now preparing for human clinical trials with the goal of making the treatment publicly available by 2030.

If successful, this therapy could transform dental care by giving people a third chance at growing their own teeth.

The science builds on decades of regenerative medicine research and the discovery that humans may have dormant “third set” tooth buds, much like animals such as sharks and elephants that naturally grow multiple sets of teeth.

Combined with ongoing advances in bone and dental pulp regeneration, scientists believe this approach could one day reverse tooth loss caused by genetics, injury, or aging. Within the next decade, what was once science fiction—regrowing teeth naturally—may become an everyday reality for patients around the world.

Read the paper here:
Ravi, V., Murashima-Suginami, A., Kiso, H., Tokita, Y., Huang, C.L., Bessho, K., Takagi, J., Sugai, M., Tabata, Y., Takahashi, K. Advances in tooth agenesis and tooth regeneration. Regenerative Therapy, Vol 22, March 2023, Pages 160–168.

What are your thoughts on this potential breakthrough? How could this change the future of dentistry?

For educational purposes. This content is based on publicly available scientific research.

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