Доктор Клиндухов Илья Анатольевич

06/05/2025

Early pregnancy symptoms can vary, but some of the most common include a missed period, light bleeding or spotting, breast changes, fatigue, and nausea or vomiting. Other possible early symptoms include increased urination, mood swings, and food cravings or aversions.

Youtube: https://www.youtube.com/
_______________________

F.B page: https://www.facebook.com/Ali1.ultrasound
_______________________

Google: Ali Ultrasound diagnostic services AUDS
_______________________

whatsapp.com: https://whatsapp.com/channel/0029VaOlAdw7j6g1FNkL4C2b
_______________________

Contact ▶ 0324 4117987

06/05/2025

Endometriosis is a common cause of pelvic pain affecting approximately 10% of reproductive-age women.

This narrative review summarizes the epidemiology, pathophysiology, diagnosis, and treatment of endometriosis. https://ja.ma/43ptzB1

05/05/2025

AJOG Expert Review: Single-cell technology: the key to an improved understanding of the human endometrium in health and disease - Single-cell RNA-sequencing analysis: distinguishing the normal and tumorigenic endometrium https://www.ajog.org/article/S0002-9378(24)00897-4/fulltext

05/05/2025

AJOG Expert Review: Uterine fibroids at single-cell resolution: unveiling cellular heterogeneity to improve understanding of pathogenesis and guide future therapies https://ow.ly/Tzz250VJx7n

28/04/2025

AJOG Expert Review: The adult o***y at single cell resolution: an expert review - A schematic overview of selected single-cell studies on adult pre-menopausal human ovaries
Key findings from studies conducted on ovarian tissue, manually isolated follicles, and oocyte collected during IVF treatments are illustrated, along with areas that have not yet been addressed by single-cell studies. https://ow.ly/Z31F50VIjQ2 ***y American College of Obstetricians and Gynecologists - ACOG American Society for Reproductive Medicine

20/04/2025

A novel pelvic magnetic resonance imaging measurement for pelvic organ prolapse evaluation - AUPCL measurement in the midsagittal plane
A, The AUPCL (area enclosed by blue dashed and solid lines) is defined as the sectional area bordered by the PCL (blue dashed line) superiorly and a curve (blue solid line) approximating the superficial edge of the UT, V, PB, ASC, and LP. The white lines delineate the boundaries of individual pelvic structures, which collectively form the inferior border of the AUPCL. AUPCL measurement: 25.8 cm2. B, Representation of the AUPCL (shaded blue area) in a patient with severe prolapse. AUPCL measurement: 33.9 cm2. https://ow.ly/cJ3e50VzVx6

17/04/2025

Cesarean scar niche: comparison of transvaginal ultrasound findings and uterine tissue samples after hysterectomy - Cesarean scar niche (internal)
A, An internal niche is characterized by a defect in the internal border of the cesarean scar site measuring more than 2 mm. The black dots represent residual myometrial thickness, while the white dots indicate adjacent myometrial thickness. B, The patient's uterus exhibited the formation of 2 distinct niches. C, The images depict an internal niche at the cesarean scar site, 1) internal niche, 2) adjacent myometrial thickness was defined as the distance between the serous layer and the endometrium up to 1 cm above the base of the defect where the myometrium is thickest, 3) residual myometrial thickness was defined as the distance between these 2 layers at the apex of the scar. D, Transvaginal ultrasonography of a cesarean scar niche. 1) Adjacent myometrial thickness, 2) residual myometrial thickness, 3) niche height, and 4) niche length. https://ow.ly/JOWR50VzBbe

28/03/2025

Declining ovarian function is a common cause of infertility among women in their late 30s to early 40s.

This JAMA Patient Page describes ovarian aging, its effect on fertility, and strategies to address infertility due to ovarian aging. https://ja.ma/3Y5vAQC

21/03/2025

21/03/2025

Tool for classifying tumor structural variants

Genomic structural variants (SVs) are key to understanding cancer and can inform treatment response.

Distinguishing cancer from normal SVs has the limitation of requiring paired normal samples.

The researchers looked at similarities and differences between 2 million germline and 115 thousand tumor SVs from a cohort of 963 patients from The Cancer Genome Atlas.

They identified features linked to transposon-mediated processes that are associated with germline SVs, while somatic SVs more frequently show features characteristic of chromoanagenesis.

The results enabled the authors to introduce the -Germline and Tumor Structural Variant (GaTSV), a classifier that accurately identifies cancer-specific SVs without matched normal tissue, based on genomic sequence context differences.

https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(25)00027-X
https://sciencemission.com/classifying-tumor-structural-variants