The Endocrine Club

The Endocrine Club General endocrinology and diabetes practical points
Chairman/admin :
Abdulqawi Almansari MBBS FACP FACE

Chairman Abdulqawi Almansari MD FACP FACE
Consultant endocrinologist
Myclinic alsafa Jeddah
American board of Endocrinology Diabetes and Metabolism2000
American Board internal Medicine 1998

08/05/2026

54 F HTN not controlled on Perndopril 5 mg what is the next step
1- increase Perindopril 10 mg
2- Add amkodipine 5 mg
3- Add Indapamide or HCTZ

08/05/2026

We recommend a short corticotropin test (250g) as the “gold standard” diagnostic
tool to establish the diagnosis. If a short corticotropin test is not possible in the first instance, we recommend an initial screening procedure comprising the measurement of morning plasma ACTH and cortisol levels.

Endo Society 2016

08/05/2026

Adding Ezetimibe to a Lower Statin Dose may be Better Tolerated with Forceful Reduction of LDL-c/Non-HDL-c than increasing statin
NICE 2022

08/05/2026

Apoplexy (sudden hemorrhage or infarction) of a microprolactinoma during pregnancy is rare but serious complication, characterized by sudden headache, visual disturbances, and vomiting
Review Eur J Endocrinol May 24;185(1):99-108.

08/05/2026

S Vit B12 Less than 180 nanograms (133 pmol) per litre is considered Confirmed vitamin B12 deficiency
NICE 2024

07/05/2026

We suggest that In PAI ( Primary Adrenal Insuffeciency) based on the individual clinical course, an increase in hydrocortisone dose should be implemented,
in particular during the third trimester

Endo Society 2016

07/05/2026

There is no role for routine testing for insulin, C-peptide, or proinsulin in most patients with diabetes. Differentiation between type 1 and type 2 diabetes may be made in most cases on the basis of the clinical presentation and the subsequent course. These assays are useful primarily for research purposes. Occasionally, C-peptide measurements may help distinguish type 1 from type 2 diabetes in ambiguous cases, such as patients who have a type 2 phenotype but present in ketoacidosis.

ADA Position Statement Executive Summary 2011

07/05/2026

Metformin is recommended for patients with T2D, CKD .
The dose should be reduced to 1,000 mg daily in patients eGFR 30–44and in some patients with eGFR 45–59 who are at high risk of lactic acidosis.
ADA/KDIGO 2022

07/05/2026

This metaanalysis found that extra BP reduction from combining drugs from 2 different classes is approximately 5 times greater than doubling the dose of 1 drug
Wald et al. Am J Med 2009;122:290–300

07/05/2026

In women, loss of adrenal androgens results in loss of axillary and p***c hair.
Endo Society 2016

06/05/2026

Explain to people starting treatment with vitamin B12 replacement that their symptoms could start to improve within 2 weeks, but this may take up to 3 months
NICE 2024

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