04/11/2025
Explore AMRA’s Latest Insights In Liver Disease Research @ AASLD 2025!
November is upon us and that means it is once again time for AASLD’s The Liver Meeting®! This year, the AMRA team is thrilled to be in attendance to share updates on Saturday, November 8th from three studies using our MRI-based muscle assessment biomarkers in MASH cirrhosis research, done in collaboration with our colleagues at Virginia Commonwealth University (VCU), Indiana University (IU), and Linköping University (LiU):
➡️ “Reduced Fat and Muscle Volumes in Decompensated Cirrhosis: A Whole-Body MRI Study” | Poster #2470
➡️ “Muscle Composition Matters: MRI-Based Myosteatosis Strongly Correlates with Physical Function in Cirrhosis” | Poster #2384
➡️ “Muscle quality, defined by low muscle volume and muscle fat index on MRI, is worse in decompensated NASH cirrhosis, but not in compensated MASH cirrhosis” | Poster #2642 | Presented by Dr. Samala, IU
These poster presentations highlight AMRA’s evaluation of muscle wasting in MASH and cirrhosis. Using our muscle assessment score (MAsS) biomarkers, the studies show that the prevalence of the adverse muscle composition phenotype, defined by low muscle volume z-score and high muscle fat infiltration, increases drastically in decompensated MASH cirrhosis.
In addition, strong correlations between the MAsS biomarkers and standard physical function tests in patients with decompensated cirrhosis is demonstrated. Collectively, these studies underscore the value of AMRA’s MRI-based MAsS biomarkers for use in evaluating muscle wasting in liver disease studies.
If you’ll be in DC next week, reach out to any of our team members - Mikael Forsgren, Maria Rydfjord, or Conrad Maurais, - who will be in attendance at The Liver Meeting®. Or contact info@amramedical.com to set up some time to discuss how AMRA’s MRI-based fat and muscle biomarkers can help you transform your trials in MASH, cirrhosis, and beyond.
We can’t wait to see you in DC!