Acta Dermato-Venereologica

Acta Dermato-Venereologica Acta Dermato-Venereologica has rapid publication times and is amply illustrated with a large number of colour photographs to enhance understanding.

Acta Dermato-Venereologica (ActaDV) is a truly international Open Access journal for clinical and experimental research in the field of dermatology and venereology. Acta Dermato-Venereologica publishes high-quality manuscripts in English dealing with new observations on basic dermatological and venereological research, as well as clinical investigations. Each volume also features a number of Revie

w articles in special areas, as well as short Letters to the Editor to stimulate debate and to disseminate important clinical observations.

🔥Xeligekimab🔥 vs other IL‑17A inhibitors in patients with moderate‑to‑severe plaque psoriasis – comparable early respons...
09/05/2026

🔥Xeligekimab🔥 vs other IL‑17A inhibitors in patients with moderate‑to‑severe plaque psoriasis – comparable early response but stronger long‑term skin clearance and better infection‑related safety!

✅At week 12, PASI 75/90/100 responses are similar between xeligekimab and both comparators, with only a non‑significant numerical trend toward higher PASI 75 with secukinumab.

✅At week 52, xeligekimab achieves significantly higher PASI 100 vs secukinumab (57.8% vs 42.1%, p=0.005) and better DLQI 0/1 (68.8% vs 47.5%, p

Comparison of the Burden of Acne Vulgaris in China vs Globally: Insights from the Global Burden of Disease Study (2021) ...
29/04/2026

Comparison of the Burden of Acne Vulgaris in China vs Globally: Insights from the Global Burden of Disease Study (2021) and Projections to 2050

Authors: Rui Yuan, Haibo Long, Tian Li, Aijun Chen

The burden of acne vulgaris in China has increased over the past 3 decades, with a faster rise than the global average and a continued increase projected through 2050. Adolescents bear the main burden, and females are more affected than males. These findings highlight
the need for earlier recognition and better long-term management for adolescents and for females.

https://doi.org/10.2340/actadv.v106.adv-2025-0131

29/04/2026

A Reddish Nodule on the Scalp: A Quiz

Authors: Yuelin Li, Xiao Tan, Hong Ren, Guangquan Ji, Renqiong Chen

Clinical photos: Skin lesion on the scalp of the patient. The pathology showed confluent nests of basophilic tumour cells within the dermis, accompanied by hyaline material, foca mucin deposition and prominent fibrous tissue proliferation.

What is your diagnosis?
1: Metastatic adenoid cystic carcinoma.
2: Squamous cell carcinoma.
3: Trichilemmal carcinoma.
4: Cutaneous metastases from lung cancer

See https://doi.org/10.2340/actadv.v106.adv-2026-0426 for answer

Sun Protection Behaviours and Photosensitivity in Japanese Children: Toyama Adjunct Study of Japan Environment and Child...
29/04/2026

Sun Protection Behaviours and Photosensitivity in Japanese Children: Toyama Adjunct Study of Japan Environment and Children’s Study (JECS)

Authors: Megumi Mizawa, Kenta Matsumura, Teruhiko Makino, Akiko Tsuchida, Hidekuni Inadera, Tadamichi Shimizu

Children are exposed to much more sunlight than adults, yet little is known about how they protect their skin or how often they develop light-related skin problems. Using data from a large national child cohort in Japan, this study shows how common sun-protective behaviours are in young children and identifies family and social factors that influence these behaviours. It also reveals that some children develop skin symptoms after sun exposure without receiving a diagnosis. These findings can help parents, schools and healthcare providers improve early education, awareness and support for safe sun exposure in childhood.

https://doi.org/10.2340/actadv.v106.adv-2026-0397

Epidemiology and Comorbidity of Vitiligo in Germany: A Claims Data AnalysisAuthors: Theresa Klinger, Matthias Augustin, ...
29/04/2026

Epidemiology and Comorbidity of Vitiligo in Germany: A Claims Data Analysis

Authors: Theresa Klinger, Matthias Augustin, Susanne Baumeister, Jennifer Riedel, Claudia Grellmann, Anja Kamps, Markus Böhm, Kristina Hagenström

Vitiligo is more than just a cosmetic problem. Our study, based on 2 large data sets, sensitive case definitions, and matched comparison groups provides reliable epidemiological case numbers for vitiligo and associated comorbidities for the first time. We show that vitiligo affects many people and is often associated with other health problems such as hair loss, certain autoimmune diseases, and diabetes, but also with psychological distress such as depression or anxiety. These new findings help to better understand the full extent of the disease and underscore the need for more comprehensive, holistic care for those affected in our society.

https://doi.org/10.2340/actadv.v106.44468

Autologous Patch Healing vs Secondary Intent Healing after Mohs Micrographic Surgery: A Randomized Controlled TrialAutho...
29/04/2026

Autologous Patch Healing vs Secondary Intent Healing after Mohs Micrographic Surgery: A Randomized Controlled Trial

Authors: Marie K. Hjorth, Ewa A. Burian, Tonny Karlsmark, Mette Mogensen, Martin Glud, Anna Ahm Harager, Anthony Rossi, Katrine E. Karmisholt

This randomized controlled study investigates wound healing after facial tumour removal by Mohs micrographic surgery. The intervention group healed with a patch made from their own blood and the control group healed with secondary intent. The wounds were evaluated after surgery on day 12, 19, and after 6 months. We investigated whether there were adverse events, measured transepidermal water loss and wound size area, and evaluated clinical photos. The wounds were evaluated blinded by the Patient and Observer Scar Assessment Scale. We found no difference regarding epithelialization in the 2 groups. No clinical infection or recurrence of cancer was detected indicating that the patch method appears safe. Although not significant, wound area reduction was higher in the patch group as was change in transepidermal water loss indicating that the patch creates a moist environment. Each wound healing method was associated with high patient satisfaction.

https://doi.org/10.2340/actadv.v106.43586

The Seasonal Trend of Brittle Nails: A Google Trends Analysis of English-speaking CountriesAuthors: Eric McMullen, Mahan...
23/04/2026

The Seasonal Trend of Brittle Nails: A Google Trends Analysis of English-speaking Countries

Authors: Eric McMullen, Mahan Maazi, Jonathan Berkowitz, Matthew Berkowitz, Jeffrey Donovan

https://doi.org/10.2340/actadv.v106.adv-2025-0238

Quality of Life in a Swedish Cohort of Patients with Mycosis FungoidesAuthors: Daria Hub, Kristina Drott, Emma Belfrage,...
23/04/2026

Quality of Life in a Swedish Cohort of Patients with Mycosis Fungoides

Authors: Daria Hub, Kristina Drott, Emma Belfrage, Andreas Sonesson

Mycosis fungoides (MF) is a cutaneous T-cell lymphoma with an often indolent course and few options for curative treatment. Hence, patients with MF often live with the diagnosis for many years. Therefore, the goal of treatment is to ensure stability of patients with MF.
Our study showed that the disease’s symptoms, such as pruritus, are the factors that affect patients’ quality of life the most. Moreover, patients with higher levels of a signalling protein called thymus and activation-regulated chemokine/ chemokine (C-C) ligand 17 in the blood are in this study generally likely to have lower quality of life.

https://doi.org/10.2340/actadv.v106.adv-2026-0364

"HealthRelatedQualityofLife

Reconsidering Efficacy and Safety: A Critical Appraisal of Repurposing Anti-inflammatory Targeted Drugs in Darier diseas...
23/04/2026

Reconsidering Efficacy and Safety: A Critical Appraisal of Repurposing Anti-inflammatory Targeted Drugs in Darier disease

Authors: Estelle Burle, Juliette Mazereeuw-Hautier, Maella Severino-Freire

https://doi.org/10.2340/actadv.v106.adv-2026-0322

Noninvasive Skin Surface Sampling Identifies Elevated IL-1β and IL-6 in Paediatric Atopic Dermatitis PatientsAuthors: Am...
23/04/2026

Noninvasive Skin Surface Sampling Identifies Elevated IL-1β and IL-6 in Paediatric Atopic Dermatitis Patients

Authors: Amir Horev, Sapir Gabay, Yuliya Valdman-Grinshpoun, Topaz Alfer, Amir Szitenberg, Navit Ogen-Shtern

This study offers a painless, child-friendly method to understand atopic dermatitis (AD) in children. Instead of using invasive skin biopsies, we used special bandages to collect samples, making it much more comfortable for young patients. Our findings showed that
certain inflammatory molecules, like IL-1β and IL-6, are consistently elevated in children with AD, which helps us better understand the disease’s underlying biology. The research also reveals that these molecular patterns differ based on individual characteristics like age and gender, and different areas of the body. Ultimately, this new method provides a valuable tool for physicians to track the disease and develop future personalized monitoring and treatment strategies, with reduced discomfort to children.

https://doi.org/10.2340/actadv.v106.adv-2025-0010

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