23/10/2025
From gains to decline: effects of structured pre-dialytic exercise training and detraining on physical fitness, quality of life, and inflammation in haemodialysis patients
Authors: Shu-Chun Huang, Ji-Tseng Fang, Yu-Chieh Huang, Chun-Yueh Lin, Ching-Chung Hsiao
People receiving maintenance haemodialysis often have low endurance, weak muscles, and reduced quality of daily life, leading to poorer health outcomes. While exercise during or on non-dialysis days has shown benefits, little is known about exercising just before dialysis. In this study, patients joined a 6-month supervised programme combining aerobic and strength exercises before dialysis. The programme improved endurance, strength, muscle mass, and quality of life. Most gains faded within 3 months after training ended, except muscle mass, which was maintained. Exercise before dialysis did not change blood markers of inflammation, suggesting minimal pro- or anti-inflammatory effects. Overall, this approach was effective, and easy to follow, providing a practical alternative to existing exercise models. Sustained strategies are needed to preserve the benefits.
https://doi.org/10.2340/jrm.v57.44067