Centre for Healthy Longevity - CHL

30/04/2025

Could your “normal” vitamin levels be quietly shortening your health-span?

A new publication from the NUS Academy for Healthy Longevity shows that even mild gaps in vitamins B6, B9, B12, D and K can drain energy, blur cognition, weaken immunity, and erode bone strength, long before any clinical deficiency is flagged. Standard Dietary Reference Intakes are based on the “average” person and often ignore genetics, lifestyle, and nutrient interactions. That means many of us fall below truly optimal levels.

The study suggests that biomarker-guided, precision supplementation could help redefine what “enough” really means—supporting longer, healthier lives tailored to everyone.

This work, led by Muhammad Daniel Azlan Mahadzir, Sheryl Tan, Dr Elena Sandalova, Dr Ee Moon Chin, and Prof Andrea B. Maier, lays the foundation for setting evidence-based thresholds that personalise nutrition.

Read more: https://doi.org/10.1016/j.mad.2025.112062

Which micronutrient do you think most people overlook? B-vitamins, vitamin D, or something else? Let us know in the comments!

22/01/2025

The public registration is now open. Join us in Singapore!

Sign up at https://medicine.nus.edu.sg/trp/healthy-longevity/events/global-conference-on-gerophysics/

23/12/2024

We are thrilled to announce the world's first conference on , a new scientific discipline forging conceptual and methodological bridges between physics and biogerontology.

We welcome biologists, physicists, and professionals from other disciplines to join us in Singapore on 5-6 March 2025. Together, we aim to cultivate a shared language and interdisciplinary dialogue that lay the groundwork for a field that could transform our understanding of aging and .

ABSTRACT SUBMISSION is now open! All selected presenters will be given a FREE PASS to attend the conference. Travel grants for students and early-career researchers are available based on merits and needs.

More details at https://medicine.nus.edu.sg/trp/healthy-longevity/events/global-conference-on-gerophysics/.

13/12/2024

Join Prof. Andrea B. Maier for an immersive journey into the future of healthcare at the -accredited Healthy Longevity Intensive Course for Healthcare Professionals 2025 organized by NUS Academy for Healthy Longevity

In this 2-day program, you’ll explore the latest in gerodiagnostics, gerointervention, biomarkers of aging, oral and reproductive health, alternative medicine, and ethical considerations in healthy longevity.

Gain innovative insights, engage with leading experts, and network with like-minded professionals passionate about advancing longevity medicine.

Don’t miss this opportunity to reshape how we approach aging and health in clinical practice.

Register now at: https://www.gevme.com/healthy-longevity-intensive-course-66900791

23/10/2024

Join Prof. Andrea Maier from the Academy for Healthy Longevity for an engaging fireside chat on Thursday, October 24th at 7 PM! 🌟

📍 Venue: Trapeze Rec. Club, 27 Tanjong Pagar Rd.

Don’t miss this opportunity to explore the latest insights into healthy aging and longevity. See you there!

**Fireside chat with Prof. Andrea Maier from the Center for Healthy Longevity** Prof. Andrea B. Maier is a prolific researcher in the field of geroscience — the intersecti

21/10/2024

🚀 Registration Now Open: Founders Longevity Forum Singapore: Unlock Healthy Longevity 🚀

Be part of this landmark event hosted by Founders Forum Group in collaboration with the NUS Academy for Healthy Longevity and Longevity.Technology. Mark your calendars for February 27th-28th in vibrant Singapore!

This unique collaboration promises to bring together the best innovators and minds in longevity - clinicians, academics, investors, executives and entrepreneurs, to drive knowledge, connectivity and growth in this sector.

📍WHERE 📍

Set in Singapore, —a dynamic hub where innovation meets investment in the heart of the APAC region. With the city at the forefront of rapid technological advancements, we're setting the stage to bring together the best innovators and minds in longevity - clinicians, academics, investors, executives and entrepreneurs. Join us at the Park Royal Beach Road!

🧠 WHAT’S ON DECK?
After the morning plenary, our two-day forum will feature three key tracks:

- Clinical Longevity Interventions

- Consumer Longevity

- Longevity Investment (for investor ticket holders)
➕ Join us for an special gala dinner on Day 1—network and celebrate with industry leaders!

📝 HOW TO REGISTER 📝

This event has been tailored for current academics and clinicians within the longevity field, biotech and consumer health founders & executives, pharma executives, corporate executives, and investors.

To register, start by completing this questionnaire. If you’re eligible, you’ll receive a link to complete registration to determine your eligibility and ticket type. Following this, if you are eligible you will receive a link to register.

Questionnaire: https://lnkd.in/epR7ySdi
We hope to see you there!

18/10/2024

Can multivitamins and mineral supplementation reduce biological age?

We are excited to announce the launch of recruitment for our CEDIRA clinical trial, studying the effects of multivitamins and mineral supplements! Register here: https://nus.syd1.qualtrics.com/jfe/form/SV_2fb8G29nLfl1U7s

27/09/2024

Our new research reveals that high conscientiousness in middle-aged and older adults, typically linked to better health, may also increase the likelihood and severity of suicidal behavior, particularly among those struggling with depression.

Interestingly, this association diminishes in those with severe physical illness, suggesting that conscientiousness might influence su***de risk differently based on health status. Read full paper here: https://doi.org/10.1016/j.comppsych.2024.152523

26/09/2024

Our latest research revealed that protein supplementation boosts muscle mass in community-dwelling older adults. Surprisingly, the effect is consistent regardless of the dose, frequency, or timing of the supplementation.

Key takeaways:
- Protein supplementation boosts muscle mass, especially in those living independently.
- The effectiveness of protein supplementation in boosting muscle mass is not significantly influenced by the dose (≥30g vs.

25/09/2024

In our latest research, we delve into the cutting-edge role of lipids in ageing and how lipidomics might be the key to unlocking healthier, longer lives. Our review explores how lipid profiles could serve as biomarkers of healthy ageing and even lead to the development of a "lipid clock" to predict future health outcomes.

This breakthrough could revolutionize precision medicine and boost healthy longevity.

Read the full paper here: https://doi.org/10.1016/j.arr.2024.102432

24/09/2024

Scientists are closer than ever! Biomarkers of aging, which help predict how our bodies age, are showing promise for improving health as we get older. But there’s a catch—translating these discoveries into everyday healthcare has been tricky. This new research by experts, including Prof. Andrea Maier, highlights the biggest challenges and what needs to be done to bring these amazing tools into clinical settings. From making them more affordable to ensuring they work for everyone, the recommendations pave the way for a healthier future!

23/09/2024

Did you know your gut might hold the secret to aging well? 🌱🧠
Researchers at NUS have uncovered how certain gut bacteria change as we age. Led by Prof. Andrea Maier, the study found that some microbes may help us live healthier, longer lives. This could lead to new ways to improve health in old age!
Curious about the details? Check it out here: https://www.nature.com/articles/s41467-024-52097-9