Academic Medicine Research Institute - AMRI

Academic Medicine Research Institute - AMRI ​The Academic Medicine Research Institute (AMRI) is a one-stop research enabler that provides admi

Join the conversation on designing and implementing equitable AI in real-world care!Hear from Clin Asst Prof Alvin Ngeow...
24/04/2026

Join the conversation on designing and implementing equitable AI in real-world care!

Hear from Clin Asst Prof Alvin Ngeow, Clin Assoc Prof Oh Choon Chiat, Prof Nick Sevdalis, and Clin Assoc Prof (Dr) Tan Ngiap Chuan as they explore how the nature of technology-driven innovation, clinical need, patient perspectives, and organisational support interact to determine implementation success.

Sign up now at https://for.sg/rgr20may or scan the QR code in the image below!

Singapore General Hospital
SingHealth Polyclinics
SingHealth
National University of Singapore



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

  Radioembolization-induced liver disease (REILD) is a potentially life-threatening complication that can develop after ...
23/04/2026

Radioembolization-induced liver disease (REILD) is a potentially life-threatening complication that can develop after yttrium-90 (Y-90) radioembolization.

Researchers from Singapore General Hospital(SGH) were determined to find associations between liver toxicity and Y-90 dosimetry.

Their study observed severe liver toxicity at absorbed doses below the recommended dose thresholds to nontumorous liver. Albumin-bilirubin (ALBI) scores greater than or equal to 2 predicted for postprocedural liver toxicities.

Read more in Nuclear Medicine Communications, Wolters Kluwer: https://bit.ly/4pDvniI

AMC researchers involved: Joanna Rui En Fong, Kaina Chen, Charles Xian Yang Goh, Hian Liang Huang, Kelvin Siu Hoong Loke, Aaron Kian Ti Tong



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

How are we advancing immunotherapy and precision care for chronic Hepatitis B?  At our latest Research Grand Rounds, Pro...
21/04/2026

How are we advancing immunotherapy and precision care for chronic Hepatitis B?

At our latest Research Grand Rounds, Prof Antonio Bertoletti and Asst Prof Nina Le Bert shared how emerging immune monitoring tools and novel immunotherapeutic strategies are reshaping HBV management. From siRNA-based treatments to therapeutic vaccines, these approaches aim to restore immune function and enable more personalised care.

Attended by more than 350 participants, the session was moderated by Dr Daniel Mahadzir from SingHealth Duke-NUS Global Health Institute.

Thank you to all who joined us! Missed the session? Catch up on the highlights here: https://for.sg/rgr-15-apr-2026

Duke-NUS Medical School
SingHealth Duke-NUS Global Health Institute
SingHealth

17/04/2026

Save the date for the next Research Grand Rounds on 20 May at 12.30pm!

Dive into designing and implementing equitable AI in real-world care.

More details coming soon!

Clin Asst Prof Alvin Ngeow
Clin Assoc Prof Oh Choon Chiat
Prof Nick Sevdalis
Clin Assoc Prof (Dr) Tan Ngiap Chuan

Singapore General Hospital
SingHealth Polyclinics
SingHealth
National University of Singapore



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

  Recent clinical studies have alluded to an association between chronic rhinosinusitis (CRS) and cognition, possibly me...
16/04/2026

Recent clinical studies have alluded to an association between chronic rhinosinusitis (CRS) and cognition, possibly mediated by local and systemic neuroinflammation.

Researchers from Sengkang General Hospital, SingHealth, Duke-NUS Medical School, Singapore National Eye Centre / Singapore Eye Research Institute performed a meta-analysis to clarify the association of CRS diagnosis or treatment with cognitive function and dementia.

Their findings showed that CRS is associated with 9% poorer global cognitive function, while CRS treatment is associated with 8-9% improvements in processing speed and working memory.

Read more in Rhinology, European Rhinologic Society: https://bit.ly/3L0VzoI

AMC researchers involved: Esther Yanxin Gao, Benjamin Kye Jyn Tan, Kai Lin Chan, Claire Jing-Wen Tan, Liu Xuandao, Laura Tay, Ecosse Lamoureux, Neville Wei Yang Teo, Tze Choong Charn



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

This International Biomedical Laboratory Scientists (BLS) Day, we celebrate our research community driving innovation an...
15/04/2026

This International Biomedical Laboratory Scientists (BLS) Day, we celebrate our research community driving innovation and advancing translational , turning laboratory insights into meaningful impact for patients and healthcare systems.

In line with this year’s theme, “Biomedical Laboratory Scientists Promoting Sustainability in Clinical Diagnostics,” we also recognise the growing importance of integrating sustainable practices into research and diagnostic innovation. 🌱

Here’s to the people behind the science️ 🧪

SingHealth
Duke-NUS Medical School



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

  One more day to our Research Grand Rounds on Advancing Immunotherapy for Chronic Hepatitis B: From Immune Monitoring t...
14/04/2026

One more day to our Research Grand Rounds on Advancing Immunotherapy for Chronic Hepatitis B: From Immune Monitoring to Novel Therapeutic Strategies ⏰ – register now at https://for.sg/rgr15apr!

Interested in learning how advances in immune monitoring are reshaping the fight against chronic Hepatitis B Virus (HBV)?

Join Prof Antonio Bertoletti, Asst Prof Nina Le Bert and Dr Daniel Mahadzir as they share insights into how emerging immunotherapeutic strategies are advancing immunotherapy and precision care for chronic hepatitis B.

Sign up now at https://for.sg/rgr15apr or scan the QR code in the image below!

Duke-NUS Medical School
SingHealth
SingHealth Duke-NUS Global Health Institute



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

Healthcare transformation isn’t just about new technology – it's about changing how we think. 💡 📊  Meet Assoc Prof Sean ...
10/04/2026

Healthcare transformation isn’t just about new technology – it's about changing how we think. 💡 📊

Meet Assoc Prof Sean Lam, your not-so-usual scientist who proves that impactful healthcare hashtag doesn’t only happen at the bench or bedside – it happens in systems, models and data.

As a Deputy Director of the SingHealth Health Services Research Centre (HSRC) and Head of Data Science at SingHealth Duke-NUS Academic Medical Centre, he combines a foundation in modelling and optimisation with data science and systems thinking to improve health services delivery at scale.

During COVID-19, his predictive modelling work across institutions including Singapore General Hospital demonstrated that healthcare capacity is not fixed – it is dynamically expandable.

Catch the full interview here: https://for.sg/interview-with-assoc-prof-sean-lam

Healthcare transformation isn’t just about new technology – it's about changing how we think. 💡 📊 Meet Assoc Prof Sean Lam, your not-so-usual scientist who proves that impactful healthcare doesn’t only happen at the bench or bedside – it happens in systems, models and data. A...

  Knee osteoarthritis (OA) is a prevalent degenerative joint disease that affects the tibiofemoral and patellofemoral jo...
09/04/2026

Knee osteoarthritis (OA) is a prevalent degenerative joint disease that affects the tibiofemoral and patellofemoral joints, subchondral bone, and adjacent soft tissues.

Researchers from Changi General Hospital (CGH) conducted a randomised, controlled, double-blind clinical trial at an outpatient specialist medical centre according to the CONSORT guidelines.

Their findings showed that both hyaluronic acid with platelet-rich-plasm (HA+PRP) and HA treatments were effective in reducing pain and improving function in patients with knee OA over 12 months. While HA demonstrated greater early pain relief, the addition of PRP was associated with a significant reduction in bone marrow oedema at 12 months.

Read more in Journal of Clinical Medicine, MDPI: https://bit.ly/4nHWGbr

AMC researchers involved: Mandy Zhang, Kelvin Chew, Mon Hnin Tun, Victor Tan, Chung Sien Ng, Benedict Tan

Collaborators: Patrick Goh (Sports Medicine International), Kenneth Sheah (Imaging Consulting), Baoying Lim (SportsIN Orthopaedic Clinic)



Visit Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

This World Health Day, as global attention turns to Universal Health Coverage, the goal of ensuring everyone can access ...
07/04/2026

This World Health Day, as global attention turns to Universal Health Coverage, the goal of ensuring everyone can access the care they need is more important than ever.

“ezyMRI began with a simple question: how do we bring MRI closer to the patients who need it most? With SCOUT and SHIP’s guidance in protecting and translating our innovation, we are turning that vision into a point-of-care platform that expands access and supports more equitable healthcare.” - Asst Prof Le Thu Thao, Lead PI

ezyMRI, a portable MRI system developed through a clinician-engineer collaboration between Asst Prof Thu-Thao Le (Principal Investigator) from National Heart Research Institute Singapore (NHRIS), National Heart Centre Singapore and SUTD Singapore University of Technology & Design (SUTD), aims to bring magnetic resonance imaging (MRI) closer to patients beyond traditional hospital settings.

With support from SingHealth Intellectual Property (SHIP) and SingHealth Technology Incubator (SCOUT), the research team is advancing towards clinical validation and commercialisation, demonstrating how the SingHealth Duke-NUS AMC translational research ecosystem transforms research into real-world impact.

Catch the full interview here: https://for.sg/world-health-day-2026

Team ezyMRI includes: Thu-Thao Le, Shaoying Huang, Nicole Hoong, Heng Jing Han, David Ticacala, Muhammad Adam, Su Boyang, Bao Ru Leong, Tim K*m (Peter) Cheng, Calvin Chin, Yew Lok Woo, Tan Eu Jin, Tang Zilu, Lai Si Yuan

This World Health Day, as global attention turns to Universal Health Coverage, the goal of ensuring everyone can access the care they need is more important than ever. “ezyMRI began with a simple question: how do we bring MRI closer to the patients who need it most? With SCOUT and SHIP’s guidanc...

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