20/04/2025
✅ Normal WBC Differential (% of total leukocytes)
Neutrophils - 55–70%
Lymphocytes - 20–40%
Monocytes - 2–8%
Eosinophils - 1–4%
Basophils - 0.5–1%
🔹 Interpretation by Cell Type
Neutrophils ↑
✔️ Bacterial infections
✔️ Acute inflammation
✔️ Steroid use (demargination)
✔️ Left shift = ↑ bands (immature neutrophils)
Lymphocytes ↑
✔️ Viral infections (e.g., EBV, CMV)
✔️ Chronic infections (e.g., TB)
✔️ Leukemias (CLL)
Monocytes ↑
✔️ Chronic inflammation
✔️ Recovery phase of infection
✔️ Malignancy
Eosinophils ↑ (Eosinophilia)
✔️ NAACP Mnemonic:
* Neoplasia
* Asthma
* Allergies
* Chronic adrenal insufficiency
* Parasitic infections (especially helminths)
Basophils ↑
✔️ Chronic myeloid leukemia (CML)
✔️ Allergic reactions, myeloproliferative disorders
