StemCells21

09/02/2026

https://www.stemcells21.com/new-study-links-exosomes-to-biological-aging/

In this study, led by first authors Sandip Kumar Patel and Joanna Bons, along with corresponding author Birgit Schilling from The Buck Institute for Research on Aging, researchers found that exosomes—tiny particles released by cells—carry molecular signatures that indicate both biological aging and cellular senescence. These signatures include proteins, lipids, and microRNAs associated with inflammation, oxidative stress, and tissue remodeling. The findings could enhance our understanding of biological aging and help in developing future anti-aging therapies.

A new research paper featured on the cover of Volume 17, Issue 8 of Aging (Aging-US) was published on July 30, 2025, titled “Exosomes released from senescent

06/02/2026

https://www.stemcells21.com/this-discovery-could-let-bones-benefit-from-exercise-without-moving/

Researchers have discovered a biological switch that explains why movement keeps bones strong. The protein senses physical activity and pushes bone marrow stem cells to build bone instead of storing fat, slowing age-related bone loss. By targeting this “exercise sensor,” scientists believe they could create drugs that mimic exercise at the molecular level. The approach could protect fragile bones in people who are unable to stay active.

Researchers from the Department of Medicine at the School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong (HKUMed) have identified a

28/11/2025

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01/08/2025

On July 31, 2025, SC21 Bio-Pharma Laboratories by Stem Cells 21 Co., Ltd. with the Faculty of Science, Mahidol University signed a Memorandum of Understanding (MOU) to establish a research collaboration focused on Advanced Therapy Medicinal Products (ATMPs).

The collaboration aims to:

- Advance preclinical research using ATMPs under GMP standards
- Promote the exchange and dissemination of research findings
- Drive the creation of new intellectual property that will support the development of innovative medical products and accelerate clinical advancement in Thailand.
- Drive the development of innovative products and clinical advancements

The MOU was signed by Assoc. Prof. Dr. Prasit Suwanlert, Dean of the Faculty of Science, Mahidol University, and Mr. Paul Michael Collier, Managing Director of SC21 Bio-Pharma Laboratories. The signing ceremony was witnessed by executives, faculty members, and staff at Chalermprakiat Building, Mahidol University, Phaya Thai Campus.

This collaboration aims to develop GMP-grade preclinical studies, share groundbreaking knowledge, and drive innovation in regenerative medicine and cell therapy.

The event featured inspiring talks from researchers, spotlighting the future of ATMPs and Thailand’s leadership in cell-based innovations

04/06/2025

https://sc21.com/extracellular-vesicles-evs/

Extracellular Vesicles contain biomolecules, such as RNA, proteins, lipids and carbohydrates, which play an important role in cell communication.

Recent findings have ignited huge interest in EVs for their role in intercellular communication, pathogenesis, and as possible reservoirs of biomarkers. This system has been referred to as the Bio-internet, a cellular information exchange system.

SC21 lab studies the effect of extracellular vesicles on immunomodulation, regeneration pathways, and uses novel methods for extracellular vesicle isolation from cell cultures and biological fluids.

EVs provide a new era of cellular-derived therapies in a cell-free-cell therapy manner.

Extracellular Vesicles (EVs)

01/04/2025

Enhance Stem Cell Treatments with Personalized Therapeutic Synergy

At StemCells21, we understand that the success of mesenchymal stem cell (MSC) treatments goes beyond the infusion or injection itself. The body’s internal environment must be optimized to support stem cell activity, guide their homing to damaged tissues, and promote effective regeneration. That’s where Stem Cell Treatment Supportive Therapies come in — a curated selection of personalized treatments designed to enhance MSC targeting, activation, and overall therapeutic outcome.

Why Are Supportive Therapies Important?
Stem cells are highly responsive to their surrounding biological environment. When the body is inflamed, nutritionally imbalanced, or lacking in cellular energy, stem cells may not perform optimally. By improving microcirculation, reducing oxidative stress, correcting deficiencies, and creating mild, controlled microtrauma, supportive therapies prime the body for superior stem cell engagement and regeneration.

-Enhance Stem Cell Therapy – These therapies also help to:
-Increase cellular activity and mitochondrial function
-Promote stem cell homing to target tissues
-Stimulate local tissue repair and immune modulation
-Enhance detoxification and nutrient absorption
-Extend the longevity and impact of MSC treatments

https://www.stemcells21.com/supportive-therapies/

30/01/2025

Introducing REPLAY Essentials 2 Step Face Mask - Placenta Face Mask - your ultimate secret to unlocking a radiant, age-defying complexion.

21/01/2025

Relief from Chronic Back Pain with Targeted Injections at IntelliHealthPlus Clinic

We offer cutting-edge targeted injection therapy designed to address chronic back pain conditions in real time. Using advanced regenerative treatments, our approach aims to promote recovery, reduce discomfort, and improve mobility.

Imagine a life where movement isn’t restricted by pain. Our advanced injection therapies are here to help you regain mobility, improve your quality of life, and finally feel like yourself again.

Your journey to a pain-free life starts here. Let us help you take the first step.

⊕ Learn More:
https://ihplus.com/degenerative-disc-treatment/
.
➕ Contact us for a FREE consultation :
📞+66(0)2-650-7709
📧 Info@ihplus.com
🌐 www.Ihplus.com
Line: http://nav.cx/hOGUFfo ()

14/01/2025

14/01/2025

Living with back pain? At IntelliHealthPlus Clinic by StemCells21, we offer cutting-edge targeted injection therapy designed to address chronic back pain conditions in real time.

IH+ Approach Unique...

✔️ Precision Treatments:
Advanced imaging technology ensures targeted, accurate delivery to the source of your pain.
✔️ Innovative Therapies:
Leveraging regenerative medicine, including cellular therapy solutions, for optimal healing and relief.
✔️ Personalized Care:
Tailored treatment plans based on your unique condition and needs.

Using advanced regenerative treatments, our approach aims to promote recovery, reduce discomfort, and improve mobility.

Imagine a life where movement isn’t restricted by pain. Our advanced injection therapies are here to help you regain mobility, improve your quality of life, and finally feel like yourself again. Your journey to a pain-free life starts here. Let us help you take the first step.

⊕ Learn More:
https://ihplus.com/degenerative-disc-treatment/
.
➕ Contact us for a FREE consultation :
📞+66(0)2-650-7709
📧 Info@ihplus.com
🌐 www.Ihplus.com
Line: http://nav.cx/hOGUFfo ()

01/01/2025