30/12/2025
What are causes of degenerate cells in blastocyst?
Embryo cells that get damaged or cell death in blastocyst stage during the assisted reproductive technology or embryo which is from natural fertilization. It can occur from 2 natural processes which are Necrosis and Apoptosis.
The damages that occur from Necrosis process are involved in swelling of cells and breakage of cell walls. The damages that occur from Apoptosis process is involved in development stage of cell including few cells and egg shell which is called Zona Pellucida: ZP
Also, cells will stop developing in a blastocyst stage which is due to the shrinkage of cells. It leads to damages in nucleus area, cell wall area and DNA.
The causes stated above can predict the damage rate in embryo cells. For embryo at Blastocyst Day 5 which is in good quality, the damage rate or dead rate will be