
28/07/2025
Greater Initial IOP Fluctuation Predicts Long-term Progression in PACG
The relationship was seen in an Asian population, known for greater prevalence of primary angle-closure.
IOP spikes and fluctuations may disproportionately damage the optic nerve because of anatomical constraints like shallow anterior chamber and crowded angle in primary angle-closure glaucoma, thus making these eyes uniquely vulnerable to IOP variability. What’s more, greater IOP fluctuations may disrupt homeostatic mechanisms, in turn leading to loading and unloading stress which can lead to subsequent tissue damage and VF progression.
Read more: https://www.reviewofoptometry.com/article/greater-initial-iop-fluctuation-predicts-longterm-progression-in-pacg