寶家健康管理公司 / Tcell-1原生益菌

寶家健康管理公司 / Tcell-1原生益菌 讓我們所有家族朋友攜手迎接我們的世代來臨,T-CELL「以菌制菌」新世代

🦠 高纖=養腸道菌=護大腦📚 研究重點整理1️⃣ 高纖飲食 → 強化腸道菌生態 *🧫 腸道菌分解纖維 → 產生短鏈脂肪酸(SCFAs) *🛡 丁酸(Butyrate)維持腸道屏障、降低發炎 *🔄 強化「腸–腦軸」雙向溝通 *🧠 與較低失智風...
08/02/2026

🦠 高纖=養腸道菌=護大腦

📚 研究重點整理
1️⃣ 高纖飲食 → 強化腸道菌生態
*🧫 腸道菌分解纖維 → 產生短鏈脂肪酸(SCFAs)
*🛡 丁酸(Butyrate)維持腸道屏障、降低發炎
*🔄 強化「腸–腦軸」雙向溝通
*🧠 與較低失智風險、較佳認知功能有關

2️⃣ 纖維攝取高 → 失智風險較低
*📉 高纖族群死亡風險下降 15–30%
*📊 2022年研究:高纖攝取者失智風險較低
*🦠 補充益生元3個月 → 雙歧桿菌增加、認知表現提升

3️⃣ 低纖=菌相失衡=慢性發炎
*⚠️ 阿茲海默症患者腸道中
➜ 產丁酸菌較少
➜ 發炎指數較高
*🧬 丁酸不足,腦部保護力下降

🌱 怎麼養好腸道菌?
*🌾 全穀物
*🫘 豆類
*🍎 水果
*🥜 堅果種子
*🥦 多樣植物性飲食
📌 建議每日約 25–30克膳食纖維

📣 Tcell-1 原生益菌特點
* 來自人體腸道的原生菌株
* 有助於調整腸道菌叢平衡
* 協助建立穩定腸道微生態
* 與益生元搭配,可形成「菌+菌糧」支持環境

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🦠 High Fiber = Nourished Gut Microbiota = Brain Protection

📚 Key Research Findings
1️⃣ A High-Fiber Diet → Strengthens the Gut Microbiota Ecosystem
*🧫 Gut microbiota break down fiber, producing short-chain fatty acids (SCFAs)
*🛡 Butyrate helps maintain the intestinal barrier and reduce inflammation
*🔄 Strengthens communication along the gut–brain axis
*🧠 Associated with a lower risk of dementia and better cognitive function

2️⃣ High Fiber Intake → Lower Risk of Dementia
*📉 Mortality risk reduced by 15–30% in high-fiber groups
*📊 A 2022 study showed that high fiber intake is associated with a lower risk of dementia
*🦠 Three months of prebiotic supplementation → increased Bifidobacterium levels and improved cognitive performance

3️⃣ Low Fiber Intake = Microbial Imbalance = Chronic Inflammation
*⚠️ In Alzheimer’s patients:
➜ Fewer butyrate-producing bacteria
➜ Higher inflammation indices
*🧬 Butyrate deficiency leads to reduced brain protection

🌱 How to Maintain a Healthy Gut Microbiota
*🌾 Whole grains
*🫘 Legumes
*🍎 Fruits
*🥜 Nuts and seeds
*🥦 A diverse, plant-based diet
📌 Recommended daily intake: approximately 25–30 grams of dietary fiber

📣 Tcell-1 Native Probiotics — Key Features
* Native strains derived from the human gut
* Help regulate gut microbiota balance
* Support the establishment of a stable gut microbiota
* When paired with prebiotics, they help create a supportive “bacteria + prebiotic diet” environment

高纖飲食能改善健康、延長壽命,甚至保護大腦。然而,許多人仍未達到這項「關鍵營養素」的建議攝取量。

☕️ 咖啡 × 腸道菌:關鍵不在咖啡,在「糖」🦠 1️⃣ 黑咖啡 OK,加糖才是問題 *✅ 黑咖啡:對腸道影響相對單純 *❌ 含糖咖啡(糖漿、奶精、風味拿鐵)  ➜ 高糖 + 高咖啡因  ➜ 成為腸道菌失衡的誘因 *👉 問題通常來自「添加物...
04/02/2026

☕️ 咖啡 × 腸道菌:關鍵不在咖啡,在「糖」

🦠 1️⃣ 黑咖啡 OK,加糖才是問題
*✅ 黑咖啡:對腸道影響相對單純
*❌ 含糖咖啡(糖漿、奶精、風味拿鐵)
➜ 高糖 + 高咖啡因
➜ 成為腸道菌失衡的誘因
*👉 問題通常來自「添加物」

🍬 2️⃣ 糖會改變腸道菌相
*🦠 促進「促發炎菌」增生
*📉 抑制好菌生長
*⚠️ 造成菌叢失衡(dysbiosis)
研究指出:
*添加糖可能增加腸躁症風險
*改變腸道微生物群,與代謝疾病有關

🔥 3️⃣ 糖會降低短鏈脂肪酸(SCFAs)
*❌ 抑制丁酸等SCFAs產生
*❌ 腸道內壁保護力下降
*❌ 發炎機率上升
👉 腸道屏障變弱 → 發炎惡性循環

💨 4️⃣ 腸胃不適的來源
*糖分 ➜ 血糖波動 ➜ 腸蠕動異常
*常見症狀:
🌀 脹氣
🌀 便秘
🌀 腹瀉
🌀 胃食道逆流
*📌 咖啡因 + 糖 = 胃酸分泌增加

🌿 對腸道更友善的選擇
*💧 溫水(可加檸檬)
*🍵 無糖茶(薄荷、薑茶)
*☕️ 黑咖啡 / 少量鮮乳
*🌰 用肉桂取代糖調味

📣 Tcell-1 原生益菌:
*🧬 支持原生腸道菌群平衡
*🛡 幫助維持腸道屏障健康
*🔄 協助建立穩定的菌相環境
*🌱 支持短鏈脂肪酸產生的菌群基礎

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

☕️ Coffee × Gut Microbiota: The Key Isn’t the Coffee — It’s the Sugar

🦠 1️⃣ Black Coffee Is Fine; Added Sugar Is the Problem
*✅ Black coffee: has relatively mild effects on the gut
*❌ Sugary coffee (syrups, creamers, flavored lattes):
➜ High sugar + high caffeine
➜ Can trigger gut microbiota imbalance
*👉 The real issue usually comes from additives.

🍬 2️⃣ Sugar Alters the Gut Microbiota
*🦠 Promotes the growth of pro-inflammatory bacteria
*📉 Inhibits the growth of beneficial bacteria
*⚠️ Leads to gut dysbiosis
Studies indicate:
*Adding sugar may increase the risk of irritable bowel syndrome (IBS)
*Altered gut microbiota is associated with metabolic diseases

🔥 3️⃣ Sugar Reduces Short-Chain Fatty Acids (SCFAs)
*❌ Inhibits the production of SCFAs such as butyrate
*❌ Reduces protection of the intestinal lining
*❌ Increases the risk of inflammation
👉 A weakened intestinal barrier → a vicious cycle of inflammation

💨 4️⃣ Sources of Gastrointestinal Discomfort
*Sugar → blood sugar fluctuations → abnormal intestinal motility
*Common symptoms:
🌀 Bloating
🌀 Constipation
🌀 Diarrhea
🌀 Acid reflux
*📌 Caffeine + sugar → increased gastric acid secretion

🌿 More Gut-Friendly Alternatives
*💧 Warm water (optionally with lemon)
*🍵 Unsweetened tea (e.g., mint or ginger tea)
*☕️ Black coffee or coffee with a small amount of fresh milk
*🌰 Use cinnamon instead of sugar for natural flavor

📣 Tcell-1 Probiotics
*🧬 Support a balanced gut microbiota
*🛡 Help maintain a healthy intestinal barrier
*🔄 Assist in establishing a stable microbial environment
*🌱 Support the microbial foundation for short-chain fatty acid production

你每天早上都會來一杯咖啡嗎?如果你喝黑咖啡,對你的腸道健康安全無虞。但如果你有加糖,可能會給腸道帶來麻煩。

🧓✨ 長壽的秘密,在腸道?2023年兩篇研究分別刊登於📘《Nature Aging》📗《Nature Microbiology》都指出:👉 百歲人瑞的腸道菌相,確實與一般人不同。🔬 研究一|中國廣西 1,575人研究👥 近300位百歲人瑞發...
02/02/2026

🧓✨ 長壽的秘密,在腸道?
2023年兩篇研究分別刊登於
📘《Nature Aging》
📗《Nature Microbiology》
都指出:
👉 百歲人瑞的腸道菌相,確實與一般人不同。

🔬 研究一|中國廣西 1,575人研究
👥 近300位百歲人瑞

發現重點:
🦠 人瑞腸道中出現特殊「組合菌」
▪️ 擬桿菌屬(Bacteroides)
▪️ 志賀氏菌屬(Shigella)

📌 特點:
▪️ 菌相分布平均
▪️ 擬桿菌屬表現突出
▪️ 雖然多樣性不如年輕人
▪️ 但菌群結構穩定
👉 研究推測:可能與長壽有關。

🔬 研究二|丹麥團隊研究日本176名人瑞
發現:
🌿 腸道菌「高度多樣性」
🦠 細菌多樣性高
🧬 病毒多樣性也高
特別的是:
人瑞體內的病毒
👉 幫助腸道菌穩定發展
👉 降低發炎機率
這種「菌與病毒共生平衡」
可能是長壽關鍵之一。

🔰國衛院研究員指出:
長壽必須具備三大因子:
🧬 1️⃣ 先天基因
🥗 2️⃣ 飲食習慣
🌍 3️⃣ 生活環境
其中「飲食」確實會影響腸道菌平衡,
而「菌相穩定」,是幫助健康老化的重要條件。

🌱 常見「長壽菌」有哪些?
▪️ 雙歧桿菌(Bifidobacterium)
▪️ 阿克曼菌(Akkermansia)
▪️普拉梭菌(Faecalibacterium prausnitzii)
▪️克里斯滕氏菌(Christensenella)
這些菌大多與「膳食纖維」有關。

🥣 怎麼幫助體內長出長壽菌?
多吃富含纖維與多酚的食物:
🥣 燕麥
🍎 蘋果
🥦 各類蔬果
🍓 草莓
🧅 洋蔥
🍫 可可
👉 打造「多樣、穩定、不發炎」的腸道環境。

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🧓✨ Does the Secret to Longevity Lie in the Gut?
Two studies published in 2023 in:
📘 Nature Aging
📗 Nature Microbiology
both point out:
👉 The gut microbiota of centenarians is indeed different from that of the general population.

🔬 Study 1 | Guangxi, China: A study of 1,575 people
👥 Including nearly 300 centenarians

Key findings:
🦠 A unique “combination of bacterial species” was found in the intestinal tracts of centenarians:
▪️ Bacteroides
▪️ Shigella

📌 Characteristics:
▪️ Evenly distributed gut microbiota
▪️ A prominent presence of Bacteroides
▪️ Although overall diversity was lower than in younger individuals
▪️ The microbial structure was stable
👉 Researchers speculate that this stability may be related to longevity.

🔬 Study 2 | Danish research team studying 176 Japanese centenarians
Findings:
🌿 High gut microbiota diversity
🦠 High bacterial diversity
🧬 High viral diversity
Notably, the viruses found in centenarians:
👉 Help maintain stable gut microbiota
👉 Reduce the likelihood of inflammation
This “symbiotic balance between bacteria and viruses”
may be one of the keys to longevity.

🔰 Researchers at the National Health Research Institutes (NHRI) point out that three key factors are essential for longevity:
🧬 1️⃣ Genetic predisposition
🥗 2️⃣ Dietary habits
🌍 3️⃣ Living environment

Diet plays a significant role in shaping gut microbiota balance,
and a stable gut microbiota is crucial for healthy aging.

🌱 What are some common “longevity bacteria”?
▪️ Bifidobacterium
▪️ Akkermansia
▪️ Faecalibacterium prausnitzii
▪️ Christensenella
Most of these bacteria are closely linked to dietary fiber intake.

🥣 How can you help your gut grow longevity-associated bacteria?
Eat more foods rich in fiber and polyphenols:
🥣 Oatmeal
🍎 Apples
🥦 A variety of fruits and vegetables
🍓 Strawberries
🧅 Onions
🍫 Cocoa
👉 Aim to create a diverse, stable, and low-inflammatory gut environment.

腸道菌叢影響人體免疫、代謝及神經系統等,已被多項研究證實,能左右人體健康,研究發現,只要多吃膳食纖維,採取健康的生活型態,能幫助腸道養出好菌,但是不是只要培養出好菌,就能遠離疾病、健康長壽?

🧠失智並非一夕之間發生,但我們可以一天天遠離它。越來越多研究指出:👉 阿茲海默症不只是腦病👉 可能從「腸道菌失衡」開始📚 2025《Cells》回顧研究:腸道異常 → 發炎擴散 → 影響大腦🦠 腸道菌失衡,如何影響大腦?當壞菌增加時:▪️ ...
31/01/2026

🧠失智並非一夕之間發生,但我們可以一天天遠離它。
越來越多研究指出:
👉 阿茲海默症不只是腦病
👉 可能從「腸道菌失衡」開始
📚 2025《Cells》回顧研究:
腸道異常 → 發炎擴散 → 影響大腦
🦠 腸道菌失衡,如何影響大腦?
當壞菌增加時:
▪️ 腸壁變「滲漏」
▪️ 全身發炎上升
▪️ 血腦屏障變脆弱
▪️ 有害物質(脂多醣、自由基)進入腦部
🔥 結果:
β類澱粉蛋白、Tau蛋白堆積加速
→ 神經慢性發炎
→ 認知功能下降
這就是「腸–腦軸」的影響力。

🔬 失智患者的腸道菌特徵
⬇️ 好菌減少
▪️ Eubacterium rectale
▪️ Lachnospira
⬆️ 壞菌增加
▪️ Escherichia
▪️ Shigella
❗️ 丁酸(butyrate)變少
→ 腸壁保護力下降
→ 神經保護力減弱
→ 記憶形成受影響
👉 大腦健康,其實從腸道開始。

🌱 想顧記憶?從「養腸3法」開始
1️⃣ 補對「益生元」—餵養好菌
🥬 洋蔥、大蒜、蘆筍(FOS)
🍌 綠香蕉、燕麥、冷馬鈴薯(抗性澱粉)
🍎 蘋果、奇異果(果膠、多酚)
👉 每餐至少一種

2️⃣ 補充「益生菌」
🛡 不同菌種功能不同:
Lactobacillus rhamnosus GG:改善腹瀉、調節免疫
Bifidobacterium longum:產生丁酸、減少焦慮與神經發炎
Lactobacillus plantarum:修補腸壁、降低腸漏

3️⃣ 穩定菌相基本盤
😴 睡好 → 好菌增加
🚶 運動 → 提升多樣性
🧘 壓力低 → 發炎下降

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🧠 Dementia doesn't develop overnight — but we can gradually distance ourselves from it.
A growing body of research indicates:
👉 Alzheimer's is not just a brain disease
👉 It may begin with gut microbiota imbalance
📚 A 2025 Cells review study:
Gut abnormalities → inflammation spreads → affects the brain
🦠 How does gut microbiota imbalance affect the brain?
When harmful bacteria increase:
▪️ The intestinal wall becomes more permeable
▪️ Systemic inflammation increases
▪️ The blood-brain barrier weakens
▪️ Harmful substances (lipopolysaccharides, free radicals) enter the brain
🔥 Result:
Accelerated accumulation of beta-amyloid and tau proteins
→ Chronic neuroinflammation
→ Decline in cognitive function
This is the influence of the gut–brain axis.
🔬 Gut Microbiota Characteristics in Dementia Patients
⬇️ Decreased beneficial bacteria:
▪️ Eubacterium rectale
▪️ Lachnospira
⬆️ Increased harmful bacteria:
▪️ Escherichia
▪️ Shigella
❗️ Reduced butyrate levels
→ Less intestinal wall protection
→ Weakened neuroprotection
→ Impaired memory formation
👉 Brain health actually begins in the gut.

🌱 Want to improve memory? Start with these 3 gut-health strategies:
1️⃣ Increase prebiotics — feed beneficial bacteria
🥬 Onions, garlic, asparagus (FOS)
🍌 Green bananas, oats, cold potatoes (resistant starch)
🍎 Apples, kiwis (pectin, polyphenols)
👉 Aim to include at least one of these at each meal.

2️⃣ Supplement with probiotics
🛡 Different strains have different functions:
Lactobacillus rhamnosus GG: improves diarrhea, regulates immunity
Bifidobacterium longum: produces butyrate, reduces anxiety and neuroinflammation
Lactobacillus plantarum: repairs the intestinal wall, reduces leaky gut

3️⃣ Maintain a stable gut microbiota
😴 Good sleep → increases beneficial bacteria
🚶 Regular exercise → increases microbial diversity
🧘 Low stress levels → reduce inflammation

65歲的林小姐,跟醫師抱怨自己腦霧、健忘愈來愈嚴重,連自家車號都記不起來。她擔心是失智症前兆,特地到醫院做認知功能檢查,結果卻一切正常。台北榮總遺傳諮詢科醫師張家銘表示,腦霧、健忘問題不一定出在大腦,有....

👶🏫 托嬰中心不只共學,也在「共菌」📚 根據《Nature》大型研究:▪ 入園 1 個月內 → 同班孩子腸道菌開始變得相似▪ 約 3 個月後 → 👦 來自「同學」的菌種比例 28% 👨‍👩‍👧 來自家庭的比例 20%➡️ 同學影響甚至超過家...
28/01/2026

👶🏫 托嬰中心不只共學,也在「共菌」
📚 根據《Nature》大型研究:
▪ 入園 1 個月內 → 同班孩子腸道菌開始變得相似
▪ 約 3 個月後 →
 👦 來自「同學」的菌種比例 28%
 👨‍👩‍👧 來自家庭的比例 20%
➡️ 同學影響甚至超過家人
▪ 傳播最多的是「好菌」
✔ 比菲多菌
✔ 擬桿菌
✔ 幫助消化母乳、副食品的菌種
❗ 不是急性感染的病原菌
❗ 和「環境髒不髒」關係不大
能留下來,是因為它們適合嬰兒腸道

💊 有趣發現:服用抗生素之後
嬰兒服用抗生素 → 菌群受損
👶 在托嬰中心
➡️ 更容易從「同學」獲得新菌株
➡️ 有助菌群恢復
這種「共菌機制」可能成為天然的菌相重建方式

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

👶🏫 Childcare centers not only foster shared learning, but also “shared gut flora.”
📚 According to a large-scale study published in Nature:
▪ Within one month of enrollment → children in the same class begin to develop similar gut flora.
▪ After approximately three months:
👦 28% of a child’s bacteria come from classmates
👨‍👩‍👧 20% come from family
➡️ Classmates exert an even greater influence than family members.
▪ The most prevalent bacteria are beneficial ones:
✔ Bifidobacteria
✔ Lactobacilli
✔ Bacteria that help digest breast milk and complementary foods
❗ Not pathogens that cause acute infections
❗ Not significantly related to “environmental cleanliness”
They persist because they are well-suited to an infant’s gut environment.

💊 An interesting finding: After taking antibiotics,
Infants who receive antibiotics → experience gut microbiota disruption.
👶 In daycare settings,
➡️ It becomes easier for them to acquire new strains of bacteria from classmates
➡️ Which supports gut microbiota recovery
This “commensal mechanism” may be a natural way to rebuild the gut microbiota.

托嬰中心的「同學」不只是「共學」還「共菌」。科普專家葉綠舒引述《自然》(Nature)的一篇大型期刊指出,嬰兒進入托嬰中心後的短短一個月內,同班孩子的腸道菌開始變得比較像;到了大約三個月後,孩子腸道中來自托嬰...

😴 睡不好,其實是在「打亂腸道菌」* 睡眠不足 ≠ 只是累  ➜ 直接影響腸道菌叢平衡* 腸道菌一亂  ➜ 免疫、代謝、情緒、腸道功能全被牽動📊 研究重點(2025 系統性回顧+統合分析)* 急性或長期睡眠不足  ➜ 腸道菌叢明顯失衡* 睡...
26/01/2026

😴 睡不好,其實是在「打亂腸道菌」
* 睡眠不足 ≠ 只是累
➜ 直接影響腸道菌叢平衡
* 腸道菌一亂
➜ 免疫、代謝、情緒、腸道功能全被牽動

📊 研究重點(2025 系統性回顧+統合分析)
* 急性或長期睡眠不足
➜ 腸道菌叢明顯失衡
* 睡不好 → 菌叢亂 → 健康風險上升

🧬 睡眠不足時,腸道菌會怎樣?
① 🌈 菌相多樣性下降
* 菌種越多樣
➜ 腸道越穩定、抗壓性越好
* 😵 睡不好
➜ 菌變單一、韌性下降
② 🧪 好菌減少,壞菌抬頭
* 乳酸菌(Lactobacillus)等好菌⬇️
* 與發炎、代謝失衡相關的菌⬆️
* Firmicutes : Bacteroidetes 比例上升
➜ 常見於肥胖、代謝問題
🔑 改善睡眠=調整腸道菌的關鍵開關
🛏 實用建議(直接影響菌相)
* 固定睡眠時間(假日也一樣)
* 睡前少滑手機、平板(避免藍光)
* 不吃太晚的宵夜(腸道也要休息)
* 下午後減少咖啡因
* 白天曬太陽+規律運動
➜ 有助提升菌相多樣性

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

😴 Poor sleep actually disrupts your gut microbiota.
* Sleep deprivation ≠ just being tired
➜ It directly affects the balance of your gut microbiota.
* When the gut microbiota is disrupted
➜ The immune system, metabolism, mood, and gut function are all affected.

📊 Research Focus (2025 Systematic Review + Integrative Analysis)
* Acute or chronic sleep deprivation
➜ Leads to significant imbalances in the gut microbiota.
* Poor sleep → Microbiota disruption → Increased health risks

🧬 What happens to the gut microbiota when you're sleep-deprived?
① 🌈 Decreased gut microbiota diversity
* The more diverse the bacterial species,
➜ The more stable and resilient the gut becomes.
* 😵 Poor sleep
➜ Leads to a less diverse microbiota and reduced resilience.
② 🧪 Decreased beneficial bacteria, increased harmful bacteria
* Beneficial bacteria such as Lactobacillus ⬇️
* Bacteria associated with inflammation and metabolic imbalance ⬆️
* Increased Firmicutes:Bacteroidetes ratio
➜ Commonly seen in obesity and metabolic disorders.
🔑 Improving sleep = a key lever for adjusting the gut microbiota
🛏 Practical suggestions (with direct impact on gut microbiota):
* Maintain a consistent sleep schedule (even on weekends)
* Minimize screen time and avoid blue light before bed
* Avoid late-night snacks (your digestive system needs rest)
* Reduce caffeine intake in the afternoon
* Get sunlight during the day + exercise regularly
➜ Both support greater microbiota diversity

睡眠不足不僅造成精神差、易胖這類問題!醫師提醒,越來越多研究發現:睡不好,也會影響腸道菌叢,這會牽動免疫、代謝、情緒,甚至讓身體發炎而影響健康!

🦠 腸道,不只是消化器官照顧腸道,就是在為一輩子的健康打底。🧠 腸道菌 × 腸腦軸 腸道透過「腸腦軸」24 小時與大腦對話: ✔️ 調控免疫 ✔️ 影響情緒與壓力 ✔️ 參與代謝與體重調節🌱 腸道菌能幫你: ✔️ 分解膳食纖維 ✔️ 製造維...
23/01/2026

🦠 腸道,不只是消化器官
照顧腸道,就是在為一輩子的健康打底。

🧠 腸道菌 × 腸腦軸
腸道透過「腸腦軸」24 小時與大腦對話:
✔️ 調控免疫
✔️ 影響情緒與壓力
✔️ 參與代謝與體重調節

🌱 腸道菌能幫你:
✔️ 分解膳食纖維
✔️ 製造維生素 B 群、K
✔️ 產生短鏈脂肪酸,維持腸道穩定

🛡 好菌多=身體穩定
當菌相平衡時:
✅ 抗發炎
✅ 免疫力穩定
✅ 情緒較平穩
✅ 代謝效率較好

⚠️ 最傷腸道菌
高糖飲食、加工食物、熬夜、長期壓力 👉
❌ 好菌減少
❌ 壞菌增加
❌ 發炎、肥胖、過敏、憂鬱風險上升

💊 不只抗生素會影響腸道菌
研究發現,以下藥物也可能改變菌相,影響甚至停藥後仍存在:
▪️ 抗憂鬱藥
▪️ 抑制胃酸藥(如胃藥)
▪️ 部分心血管用藥

📌 醫師共同提醒
藥物一定要依照醫囑使用,避免不必要或長期濫用。

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🦠 The gut is more than just a digestive organ.
Taking care of your gut lays the foundation for lifelong health.

🧠 Gut Microbiota × Gut–Brain Axis
The gut communicates with the brain 24/7 through the gut–brain axis, which:
✔️ Regulates immunity
✔️ Influences mood and stress
✔️ Participates in metabolism and weight regulation

🌱 Gut microbiota can help you:
✔️ Break down dietary fiber
✔️ Produce B vitamins and vitamin K
✔️ Produce short-chain fatty acids that maintain gut stability

🛡 More beneficial bacteria = a more stable body
When the gut microbiota is balanced:
✅ Anti-inflammatory effects
✅ Stable immunity
✅ More stable mood
✅ Better metabolic efficiency

⚠️ The most harmful factors for gut microbiota
High-sugar diets, processed foods, staying up late, and chronic stress can lead to:
❌ Reduced beneficial bacteria
❌ Increased harmful bacteria
❌ Increased risk of inflammation, obesity, allergies, and depression

💊 Not only antibiotics affect gut microbiota
Studies have found that the following medications may also alter the gut microbiota—and effects can persist even after discontinuation:
▪️ Antidepressants
▪️ Antacids (such as stomach medications)
▪️ Certain cardiovascular medications

📌 Medical note:
Medications should be taken as prescribed to avoid unnecessary or prolonged misuse.

現在臺灣的飲食受到西方文化的影響,越來越多的加工食品還有醃漬品,都會造成腸道菌種的破壞。必須要吃原型食物,才能確保腸道菌種健康。值得注意的是平常攝取高糖飲食、加工食物、熬夜以及壓力,其實就會讓我們的腸...

21/01/2026

🔥 過去我們以為「痛」只是發炎後的副產品,但研究發現:
👉 痛覺神經本身,可能在保護腸道

🧠 關鍵角色:TRPV1+ 痛覺神經
Cell(2022)研究在小鼠中發現:
❌ 抑制或移除痛覺神經
➡️ 腸道發炎更嚴重
➡️ 修復能力下降
➡️ 腸道菌相明顯失衡

🌱 好菌 × 痛覺神經 = 腸道保護力
補殖革蘭氏陽性Clostridium屬菌
➡️ 透過痛覺神經
➡️ 促進腸道修復、降低發炎
⚡ 關鍵訊號:P 物質
痛覺神經受損 → P 物質下降
補充 P 物質 → 恢復TRPV1+痛覺神經與腸菌協同的組織保護作用

🧬 在人類 IBD 患者也看到相同線索
腸道活檢中,痛覺神經相關基因表現異常

🌿 照顧腸道,也要善待神經
✔ 過度使用止痛或抑神經藥物、長期壓力、飲食失衡,都可能間接影響腸道修復力。
✔ 多樣化飲食、減少不必要藥物、管理壓力, 可能就是預防腸道慢性發炎的關鍵。

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🔥 We used to think pain was merely a byproduct of inflammation, but research has shown that:
👉 Pain receptors themselves may help protect the gut

🧠 Key Player: TRPV1⁺ Pain Receptors
A Cell (2022) study in mice found that:
❌ Inhibiting or removing pain receptors
➡️ Led to more severe gut inflammation
➡️ Reduced repair capacity
➡️ Significant gut microbiota imbalance

🌱 Beneficial bacteria × Pain receptors = Gut protection
Proliferation of Gram-positive Clostridium bacteria
➡️ Acts through pain receptors
➡️ Promotes gut repair and reduces inflammation
⚡ Key signal: Substance P
Damage to pain nerves → decreased Substance P
Supplementing Substance P → restored the tissue-protective function of TRPV1⁺ pain nerves and gut microbiota collaboration

🧬 Similar findings in human IBD
Intestinal biopsies from IBD patients show abnormal expression of pain nerve–related genes

🌿 Taking care of the gut also means treating the nerves kindly.
✔ Overuse of painkillers or nerve-suppressing medications, chronic stress, and dietary imbalance can all indirectly impair gut repair.
✔ A diverse diet, minimizing unnecessary medications, and managing stress may be key strategies for preventing chronic intestinal inflammation.

https://health.ltn.com.tw/article/breakingnews/5308560

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🦠 胰臟癌=癌王 ➜ 死亡率高、早期難發現 * 🔬 近年研究發現: 腸道菌是被長期低估的關鍵角色🚪 當腸道失守,風險就打開了* 🧱 正常情況:腸道屏障會把細菌關在腸道* ⚠️ 若長期: @ 高油高糖飲食 @ 慢性發炎 @ 壓力過大、代謝失衡...
19/01/2026

🦠 胰臟癌=癌王
➜ 死亡率高、早期難發現
* 🔬 近年研究發現:
腸道菌是被長期低估的關鍵角色

🚪 當腸道失守,風險就打開了
* 🧱 正常情況:腸道屏障會把細菌關在腸道
* ⚠️ 若長期:
@ 高油高糖飲食
@ 慢性發炎
@ 壓力過大、代謝失衡
➡️ 腸道通透性上升
👉 細菌或其代謝物可能「越界」
* 🧬 研究發現:
✔️ 胰臟腫瘤中可檢測到細菌
✔️ 部分來源正是「腸道」
* 📚 2025《British Journal of Cancer》綜論證實
➜ 腸道菌參與胰臟癌發展過程

🧨 進入胰臟後,腸道菌在做什麼?
* 增加 DNA 損傷
* 放大慢性發炎
* 干擾免疫清除癌細胞
👉 打造「適合癌細胞生存的環境」

🛡 醫師臨床 3 大建議
① 把腸道穩定當長期投資
* 固定進食時間
* 避免暴食
* 少高油、高糖、超加工食物

② 正視腸道發炎訊號
* 腹脹、排便亂
* 對食物愈來愈敏感
➡️ 是屏障鬆動的提醒,不是小毛病

③ 穩定作息=保護腸道
* 規律睡眠
* 白天接觸自然光
* 適度活動
👉 幫腸道與免疫重新對齊節奏

🥦 調整腸道菌的 2 個核心原則
① 先餵菌,再補菌
* 益生元 > 益生菌
✔️ 可溶性膳食纖維
✔️ 天然多醣體

② 益生元+益生菌一起用
有食物,好菌才留得下來
菌相才能真正定殖、回穩

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🦠 Pancreatic Cancer = The “King of Cancers”
➜ High mortality rate and difficult to detect in the early stages
* 🔬 Recent findings show:
Gut microbiota plays a key role that has long been underestimated

🚪 When the gut barrier is compromised, risk increases
* 🧱 Normal situation: The gut barrier keeps bacteria contained within the gut
* ⚠️ If long-term:
@ High-fat, high-sugar diet
@ Chronic inflammation
@ Excessive stress, metabolic imbalance
➡️ Intestinal permeability increases
👉 Bacteria or their metabolites may “cross the border”
* 🧬 Research has found:
✔️ Bacteria can be detected in pancreatic tumors
✔️ Some of these originate from the gut
* 📚 A 2025 British Journal of Cancer review confirms:
➜ Gut bacteria participate in the development of pancreatic cancer

🧨 What happens when gut bacteria reach the pancreas?
* Increase DNA damage
* Amplify chronic inflammation
* Interfere with the immune system’s ability to clear cancer cells
👉 This creates an environment that favors cancer survival

🛡 3 Key Clinical Recommendations from Doctors
① Treat gut health as a long-term investment
* Maintain regular mealtimes
* Avoid overeating
* Limit high-fat, high-sugar, and highly processed foods

② Do not ignore signs of gut inflammation
* Bloating, irregular bowel movements
* Increasing food sensitivities
➡️ These are warning signs of a weakened gut barrier—not minor issues

③ Stable lifestyle = Stronger gut health
* Regular sleep patterns
* Daytime exposure to natural light
* Moderate physical activity
👉 Helps re-align gut and immune system rhythms

🥦 Two core principles for regulating gut microbiota

① Feed bacteria first, then add more
* Prebiotics > Probiotics
✔️ Soluble dietary fiber
✔️ Natural polysaccharides

② Use prebiotics + probiotics together
With food, beneficial bacteria survive
Only then can the gut microbiota truly colonize and stabilize

胰臟癌因為死亡率偏高,向來被稱為癌王;而作家小彤自己也正在積極對抗胰臟癌。台北榮總遺傳優生科主任張家銘表示,近年不少研究發現,「腸道菌」影響胰臟癌甚鉅。「當腸道失守、壞菌進駐胰臟,胰臟癌風險,就此被打...

🦠 腸道菌失衡,代謝就會跟著亂 腸道菌失衡 ➜ 腸道內壁變脆弱 ➜ 毒素滲漏 ➜ 引發慢性低度發炎 發炎是代謝失控的幕後推手 ➜ 體重上升、血糖不穩、疲勞感加重⏳ 短短 2 週就可能改變腸道菌組成 關鍵不是補充品 ➜ 而是「你每天吃什麼」🍽...
17/01/2026

🦠 腸道菌失衡,代謝就會跟著亂
腸道菌失衡
➜ 腸道內壁變脆弱
➜ 毒素滲漏
➜ 引發慢性低度發炎

發炎是代謝失控的幕後推手
➜ 體重上升、血糖不穩、疲勞感加重

⏳ 短短 2 週就可能改變腸道菌組成
關鍵不是補充品
➜ 而是「你每天吃什麼」

🍽 吃什麼,會決定你是哪一種菌相
2024《Nutrients》綜論(26 項研究):

🍔飲食至少影響 20% 腸道菌組成

西方飲食(高糖、高加工)
➜ 養出「不利代謝」的菌
原型食物、纖維多
➜ 支持「穩定代謝」的菌

🍩 為什麼你會「突然很想吃甜的」?
某些壞菌(如念珠菌)
➜ 會刺激迷走神經
➜ 直接操控食慾

📢 大腦收到的不是「你餓了」
➜ 而是「菌在要糖」

🧘‍♂️ 菌相穩定時,身體會怎樣?
✔️ 正餐就能滿足
✔️ 不一直想吃零食
✔️ 精力穩定
✔️ 睡眠品質好

🥗 養好腸道菌的 3 大生活策略
① 少超加工,多原型
高糖、超加工食品
➜ 明顯降低菌相多樣性
全食物
➜ 幫助修復腸道生態

② 植物多樣性是王道
每週 ≥30 種植物性食物
➜ 菌相多樣性最高
每天至少 5–7 種蔬果

③ 纖維要慢慢加
🎯 目標:25–30 g/天
➕ 方法:
* 沙拉加豆類
* 白飯換藜麥
* 多一份水果
⚠️ 太快 ➜ 脹氣、腹脹

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🦠 Gut Microbiota Imbalance Disrupts Metabolism

Gut microbiota imbalance leads to:
➜ Weakened intestinal lining
➜ Toxin leakage
➜ Chronic low-grade inflammation

Inflammation is the driver of metabolic disorders
➜ Weight gain, unstable blood sugar, increased fatigue

⏳ Gut microbiota composition can change within just 2 weeks
The key is not supplements—
➜ But what you eat every day

🍽 What you eat determines your gut microbiota
A 2024 Nutrients review (26 studies) reported:

🍔Diet influences at least 20% of gut microbiota composition

Western dietary patterns (high sugar, highly processed):
➜ Encourage bacteria that impair metabolic function
Whole, fiber-rich foods:
➜ Support bacteria that promote metabolic stability

🍩 Why do you suddenly crave sweets?

Certain harmful bacteria (e.g., Candida) can:
➜ Stimulate the vagus nerve
➜ Directly influence appetite

📢 The brain doesn’t receive the message “You’re hungry”
➜ Instead, it receives “The bacteria want sugar”

🧘‍♂️ What happens when gut microbiota is stable?
✔️ Satisfied with regular meals
✔️ Fewer cravings for snacks
✔️ Stable energy levels
✔️ Improved sleep quality

🥗 3 Lifestyle Strategies for Healthy Gut Microbiota

① Less processed, more whole foods
High-sugar, ultra-processed foods:
➜ Significantly reduce microbiota diversity
Whole foods:
➜ Help repair gut integrity

② Plant-based diversity matters
≥30 plant-based foods per week
➜ Highest microbiota diversity
Aim for at least 5–7 types of vegetables + fruits daily

③ Gradually increase fiber intake
🎯 Target: 25–30 g/day
➕ Practical methods:
* Add beans to salads
* Replace white rice with quinoa
* Add an extra serving of fruit
⚠️ Increasing too quickly ➜ Bloating, abdominal discomfort

這是《掌握代謝健康》(Mastering Metabolic Health)的第三部分: 代謝健康是驅動你身體的引擎。從腸道和肝臟功能到屏幕使用時間和日照,探索建立持久韌性的關鍵。

🦠 顧腸道=打造鋼鐵免疫力* 🛡 約 70% 的免疫細胞都在腸道* 🤧 常感冒、容易累 ➜ 問題不一定是缺維生素 C ➜ 可能是腸道菌失衡👉 腸道顧好,免疫才會強🧑‍🏫 腸道菌:免疫系統的「魔鬼教官」* 🥦 好菌分解膳食纖維 ➜ 產生 短鏈...
15/01/2026

🦠 顧腸道=打造鋼鐵免疫力
* 🛡 約 70% 的免疫細胞都在腸道
* 🤧 常感冒、容易累
➜ 問題不一定是缺維生素 C
➜ 可能是腸道菌失衡
👉 腸道顧好,免疫才會強

🧑‍🏫 腸道菌:免疫系統的「魔鬼教官」
* 🥦 好菌分解膳食纖維
➜ 產生 短鏈脂肪酸(SCFAs)
* 🧱 SCFAs 的作用:
@ 強化腸道黏膜
@ 降低過度發炎
@ 防止病菌亂闖(腸漏)

🥗 日常 3 大腸道免疫守則
① 多吃「好菌的食物」(益生質)
✔ 蔬菜、洋蔥、大蒜
✔ 蘆筍、全穀類、天然纖維
② 少做破壞腸道的事
* 🍬 高糖飲食
* 🍺 過量酒精
* 💊 濫用止痛藥
➡️ 都會破壞腸道黏膜與免疫屏障
③ 適量發酵食物
✔ 無糖優格
✔ 納豆
✔ 味噌
👉 提供天然好菌,幫助菌相平衡

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🦠 Protecting Your Gut = Building Ironclad Immunity
* 🛡 Approximately 70% of immune cells reside in the gut
* 🤧 Frequent colds, easy fatigue
➜ The problem isn’t necessarily a vitamin C deficiency
➜ It could be a gut microbiota imbalance
👉 A healthy gut supports a strong immune system

🧑‍🏫 Gut Microbiota: The “Drill Instructors” of the Immune System
* 🥦 Beneficial bacteria break down dietary fiber
➜ Producing short-chain fatty acids (SCFAs)
* 🧱 Functions of SCFAs:
@ Strengthen the intestinal mucosa
@ Reduce excessive inflammation
@ Prevent pathogens from invading (leaky gut)

🥗 3 Daily Gut Immunity Rules
① Eat more “good bacteria food” (prebiotics)
✔ Vegetables, onions, garlic
✔ Asparagus, whole grains, natural fiber
② Avoid things that damage your gut
* 🍬 High-sugar foods
* 🍺 Excessive alcohol
* 💊 Overuse of painkillers
➡️ These damage the gut mucosa and immune barrier
③ Eat fermented foods in moderation
✔ Sugar-free yogurt
✔ Natto
✔ Miso
👉 Provides natural good bacteria and helps balance the gut microbiota

許多人都知道「腸道是人類的第二個大腦」,但其實腸道也是抗病的免疫指揮中心。科博特診所院長劉博仁指出,人體有將近7成的免疫細胞都駐紮在腸道裡,常有患者感冒詢問是否要吃維生素C,而他則會反問患者是否肚子脹氣....

🦠🛡 為什麼一直補免疫力,卻還是常生病? 👉 因為真正的免疫指揮中心,不在白血球,而在「腸道菌」🧠 免疫力不是看數字 * 🧪 白血球正常 ≠ 免疫穩定 * 🦠 腸道菌相決定   @ 免疫要不要啟動   @ 發炎會不會失控⚙️ 腸道菌怎麼「指...
12/01/2026

🦠🛡 為什麼一直補免疫力,卻還是常生病?
👉 因為真正的免疫指揮中心,不在白血球,而在「腸道菌」

🧠 免疫力不是看數字
* 🧪 白血球正常 ≠ 免疫穩定
* 🦠 腸道菌相決定
@ 免疫要不要啟動
@ 發炎會不會失控

⚙️ 腸道菌怎麼「指揮」免疫?
* 🧈 產生短鏈脂肪酸(如丁酸)
➜ 降低慢性發炎
* 🛑 訓練免疫煞車系統
➜ 減少過敏、自體免疫
* 📡 透過腸–肺、腸–腦、腸–關節軸線
➜ 影響全身疾病風險

⚠️ 為什麼年紀越大免疫越亂?
* 📉 腸道菌多樣性下降
* 🔥 慢性低度發炎上升(發炎型老化)
* 💉 感染風險↑、疫苗效果↓

💊 益生菌不是萬靈丹,但吃對很重要
* 🎯 不同菌株,功能完全不同
* ❌ 亂吃 ≠ 有效
* ✔️ 重點是「養菌環境」
@ 益生元(膳食纖維)
@ 規律作息
@ 避免濫用抗生素

🥗 顧免疫,先顧腸道
* 🌾 高纖飲食
* 🥛 發酵食物
* 💤 穩定睡眠
* 🚶‍♀️ 規律活動

☀️☀️☀️☀️☀️☀️☀️☀️☀️☀️

🦠🛡 Why do I still get sick so often despite constantly boosting my immunity?
👉 Because the true command center of the immune system isn’t white blood cells—it’s the gut microbiota.

🧠 Immunity isn’t just about numbers.
* 🧪 A normal white blood cell count ≠ a stable immune system
* 🦠 The gut microbiota determines:
@ Whether the immune system should be activated
@ Whether inflammation gets out of control

⚙️ How does the gut microbiota “command” the immune system?
* 🧈 Produces short-chain fatty acids (such as butyrate)
➜ Reduces chronic inflammation
* 🛑 Trains the immune “braking system”
➜ Reduces allergies and autoimmune disorders
* 📡 Acts through the gut–lung, gut–brain, and gut–joint axes
➜ Influences systemic disease risk

⚠️ Why does the immune system become more disordered with age?
* 📉 Decreased gut microbiota diversity
* 🔥 Increased chronic low-grade inflammation (“inflammaging”)
* 💉 Higher infection risk and reduced vaccine effectiveness

💊 Probiotics are not a panacea, but taking them correctly is crucial
* 🎯 Different strains have completely different functions
* ❌ Random probiotic use ≠ effective results
* ✔️ The key is creating the right “growth environment”:
@ Prebiotics (dietary fiber)
@ A regular sleep schedule
@ Avoiding antibiotic overuse

🥗 To protect your immunity, start with your gut
* 🌾 High-fiber diet
* 🥛 Fermented foods
* 💤 Consistent sleep
* 🚶‍♀️ Regular physical activity

很多人以為免疫力好不好,關鍵在白血球數值或有沒有感冒,其實真正影響免疫系統走向的,是腸道裡那個我們看不見、卻天天運作的微生態世界。台北榮總遺傳諮詢科醫師張家銘表示,近年研究發現,腸道菌相不只是消化幫手...

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