
21/12/2023
Cannabidiol found effective as post-surgery pain management without side effects
A non-addictive painkiller with no side effects could change millions of lives for the better.
Cannabidiol, most commonly referred to as CBD, is an active component naturally present in ma*****na. It is the second most abundant active ingredient found in the plant and has been the subject of increasing public and scientific interest in the few years.
Despite the known and legitimate uses for this compound, there are also a lot of unfounded claims about alleged benefits and possible uses that have not been demonstrated yet. But a new paper from the New York University (NYU) comes to shed light on one thing the compound can do — and do well. According to the findings, pills laden with CBD can help reduce post-surgery shoulder pain.
Even better, the study finds no safety concerns associated with the compound when used for this role.
One less pain in the shoulder
“There is an urgent need for viable alternatives for pain management, and our study presents this form of CBD as a promising tool after arthroscopic rotator cuff repair,” says lead investigator Michael J. Alaia, MD, associate professor in the Department of Orthopedic Surgery at NYU Langone Health, in a media release.
“It could be a new, inexpensive approach for delivering pain relief, and without the side effects of anti-inflammatory drugs like NSAIDs and addiction risks linked to op**tes. Additionally, CBD has the benefit of pain relief without the psychotropic effects associated with THC or ma*****na.”
The study was carried out by researchers at the Department of Orthopedic Surgery at NYU Langone Health using a pill named ORAVEXXTM. This tablet was designed specifically to be used as a non-addictive, fast-absorbing oral CBD pain treatment option.
It found that the tablet can safely be used to manage pain following a minimally-invasive shoulder surgery procedure, namely rotator cuff surgery.
A total of 99 patients aged 18-75 from two medical locations — NYU Langone Health and Baptist Health and the Jacksonville Orthopaedic Institute — were part of the study. They were all given a low dose of Percocet following their surgery, and then randomly assigned to receive either a placebo or the CBD-containing tablet. After waiting for the effects of the op**te Percocet to wear off, each patient took their assigned tablets three times per day for two weeks. Throughout this time, the patients were asked to self-report the levels of pain they were experiencing using the Visual Analog Scale pain score.
Even on the first day of the experiment, the patients in the CBD group experienced, on average, 23% less pain than those in the placebo group. On the first and second day, the CBD patients also reported 22% and 25% more satisfaction with their pain control compared to the placebo group.