Plusmed Fertility Agency

09/05/2021

Happy Mother’s Day to all the mothers: to the Mothers we love, to the mothers we miss, the mothers with biological children, adopted children, fostered children, the women with big hearts but empty arms, to bereaved mothers 🌸

08/03/2021

Plusmed Fertility Agency wishing you happy International Women’s day! 🌷
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You all are amazing and one of a kind. Be happy, shine on and always believe in your dreams ❤️

27/02/2021

You often ask us how long the infertility treatment can last.
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In this episode Frequently Asked Questions our reproductologist, obstetrician and gynaecologist Dr. Valeria Skrypynets will explain you everything that you need to know about duration of the infertility treatment.
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Enjoy ❤️

05/02/2021

Diagnostic Value of semen analysis 🧬
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A standard semen analysis is the first test to assess male factor infertility in a couple. Semen sample with altered s***m parameters suggests male factor оf infertility and guide towards more advanced investigations, genetic testing and treatments.
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The semen analysis provides an indication of male fertility but is not an absolute test for fertility because it does not assess important aspects of s***m function, for example the ability of the s***matozoa to locate and pe*****te an egg.
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❗️ It is important to recognize that an individual’s semen quality can vary considerably between samples, even in men with normal semen parameters. As a result, at least two or three semen analyses are needed, each several weeks apart, in order to get a good idea of an individual’s average semen quality.
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🔺 The finding of no s***matozoa in the ej*****te (called azoos***mia) suggests either an absence of s***m production or obstruction to s***m outflow. It is most important to examine an azoos***mic semen sample carefully whether the ej*****te contains even a few s***matozoa. If a few s***matozoa can be found (called ‘virtual’ azoos***mia), the technique of single s***m microinjection may be successful.
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🔺 S***m motility is often impaired in men with idiopathic (meaning the cause unknown) poor s***m production. However, there are other important conditions which predominantly effect s***m motility, such as s***m autoimmunity, a condition that accounts for about 6% of male infertility.
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🔺 S***matozoa shape is an important predictive indicator of s***m fertilizing ability. Compared with other species, human beings have a relatively small percentage of s***matozoa showing a normal morphology, with just 15% normal forms being regarded as the lower limit of normal.
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Despite its deceptive simplicity, routine semen analysis requires attention to details to maximize its diagnostic usefulness. It is also a valuable tool in discussing the likelihood of spontaneous pregnancy over a given period of time and/or the possible need for assisted reproduction.
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👨🏻‍⚕️ Oleh Chernichenko - Urologist/andrologist in Medical Center “Plusmed”

A standard semen analysis is the first test to assess male factor infertility in a couple. Semen sample with altered s***m parameters suggests male factor оf infertility and guide towards more advanced investigations, genetic testing and treatments. The semen analysis provides an indication of male...

23/01/2021

Is s*xual abstinence of a man important before using ART?
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We have asked ourselves this question and conducted our own research❗️
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In order to study the quantitative indicators of the semen analysis and the extent of s***m DNA fragmentation depending on the time of abstinence of men, we have analyzed the test results of 193 men aged 20 to 55 years. Indicators of semen analysis were calculated manually in the Makler chamber.
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The analysis of the obtained data revealed an authentic increase over the time of abstinence of the amount of ej*****te, the concentration of s***matozoa per 1 ml of ej*****te on average, the total number of s***matozoa. In addition, the percentage of total motile s***matozoa, as well as progressively motile s***matozoa, increases with time of abstinence. The optimal indicators for fertilization are on the 6-8 day of abstinence.
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With increasing abstinence time, we observed an authentic increase in the extent of s***m DNA fragmentation. The optimal abstinence time for the extent of s***m DNA fragmentation is 1-2 days, with which the indicator increases.
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A number of trends have been identified:
🔻 There was a slight increase in the morphology range of normal s***m forms. With the time of abstinence, the percentage of immotile s***matozoa decreases. The share of non-progressive motile s***m decreased by 1–1.2%.
🔺 In 193 patients there was an increase in the concentration and total number of s***m, the share of motile, progressive motile s***matozoa and morphology indicators of normal s***m forms, which has positive effect for fertilization, however, increases also the extent of s***m DNA fragmentation, which negatively affects fertilization.
Optimal important indicators of the semen analysis are on the 6 - 8 day, and the extent of s***m DNA fragmentation – 1 - 2 day of abstinence.
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Therefore, 2 days of abstinence is optimal for ICSI fertilization to maintain a low level of s***m DNA fragmentation. While for IUI - it was recommended to have 5 days of abstinence in order to maintain a sufficient level of DNA fragmentation and a high percentage of progressive motile s***matozoa.
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👨🏽‍⚕️ Fedir Kurtiak - Head of the Embryology Department of Plusmed Medical Center

⠀We have asked ourselves this question and conducted our own research! In order to study the quantitative indicators of the semen analysis and the extent of s***m DNA fragmentation depending on the time of abstinence of men, we have analyzed the test results of 193 men aged 20 to 55 years. Indicat...

12/01/2021

New year, new episode of Frequently asked Questions with our reproductologist, obstetrician and gynaecologist Dr. Valeria Skrypynets 🧑🏼‍⚕️
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And today you can find out how to determine the endometrial implantation window.
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Enjoy 💙

01/01/2021

Plusmed Fertility Agency wishing that the new year will bring joy, love, peace, and happiness to you. 🎄
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Wishing you a Happy New Year 2021, from our hearts to yours ❤️

05/12/2020

Male infertility and obesity
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Infertility is a serious medical and social problem. The frequency of infertile couples is constantly increasing.
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The male factor of infertility occurs with almost the same frequency as the female’s and has been constantly progressing for the last 50 years.
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Obesity is considered to be one of the reasons for the alteration of reproductive system.
Being overweight suppresses testosterone, stimulates the female hormone estradiol, inhibits s***m production, reduces s*xual function, causes insulin resistance and leads to diabetes, hypertension and their bad consequences.
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Obesity is determined by body mass index (BMI) using the formula: body weight (kg)/height (m2)
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Studies have shown that overweight (BMI 25-29 kg/m2) and obesity (BMI> 30 kg/m2) in men significantly increases the incidence of infertility.
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How to start the diagnosis from the view of an andrologist❓
🔺 Semen analysis (s***mogram) + Test for S***m DNA Fragmentation.
🔺 Hormonal reproductive profile (total testosterone, free testosterone, FSH, LH, prolactin)
🔺 Carbohydrate metabolism (glucose, insulin, C-peptide, glycosylated hemoglobin, HOMA index)
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How to treat❓
🔺 Low-calorie diet aimed at weight loss. Quitting smoking and alcohol.
🔺 Regular aerobic exercise of medium intensity (morning exercise, hiking, swimming, running) lasting 30-45 minutes from 3 to 5 times a week, as well as any other possible set of exercises.
🔺 Pharmacological correction of carbohydrate metabolism disorders if necessary
🔺 Treatment of endothelial dysfunction
🔺 Antioxidant therapy if necessary
🔺 Restoration of testosterone function and inhibition of estradiol (female
s*x hormone) if necessary.
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It is recommended to treat such patients mutually by andrologist and endocrinologist. It’s also important to follow gynecologist’s recommendations for the female partner in order to achieve the common goal and become happy parents.
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Remember that the absence of obesity is not just reproductive health, but also high quality of life and a guarantee of longevity!
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👨🏻‍⚕️ Oleh Chernichenko - Urologist/andrologist in Medical Center “Plusmed”

Infertility is a serious medical and social problem. The frequency of infertile couples is constantly increasing.⠀The male factor of infertility occurs with almost the same frequency as the female’s and has been constantly progressing for the last 50 years.⠀Obesity is considered to be one of t...

12/11/2020

New episode of “Frequently asked questions” is now available 😍
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Today our reproductologist, obstetrician and gynaecologist Dr. Valeria Skrypynets talks about hyperstimulation syndrome. Enjoy 💙

24/10/2020

Intrauterine insemination (IUI) 🧬
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One of the simplest forms of infertility treatment, the main task of which is to increase the number of s***m that reach the egg and fertilize it independently, is intrauterine insemination (IUI).
It involves transfer of the s***m into the uterine cavity to facilitate fertilization.
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Treatment using IUI may be recommended in the following cases:
🔺infertility of unclear genesis
🔺ovulation factor infertility
🔺cervical factor infertility
🔺female immunological reactions to s***m
🔺male subfertility
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How to prepare❓
This procedure requires clear preparation, which includes:
🔺 preparation of a s***m sample. For IUI, we can use your partner's s***m, which he will provide directly at our medical center, or use frozen s***m or donor s***m.
Then the ej*****te will undergo a special treatment to separate the highly active s***m from the low-quality s***m and to release the s***m from the immature elements, which in turn can cause an allergic reaction.
🔺 observation of ovulation. The timing of IUI plays a major role, so it is very important to monitor for appearance of signs of expected ovulation.
🔺selection of the optimal time for the procedure. Most IUI procedures are performed in a day or two after the onset of ovulation. To do this, our doctor will draw up a scheme that you will clearly follow and comply the recommendations provided to you.
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The stages of IUI:
🔻The first stage. Appointment with a gynecologist, during which an ultrasound examination will be performed, if necessary - a procedure to determine the patency of the fallopian tubes, and other tests.
The partner needs to do a semen analysis.
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🔻The second stage. The partner must provide the semen on the day of the IUI procedure. Then the doctor using a soft thin catheter through the cervical canal will insert previously prepared semen into the uterine cavity.
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Plusmed Fertility Agency can offer:
🔺consultation and full support of a gynecologist-reproductologist
🔺 wide choice of young, healthy and carefully examined donors
🔺anonymity
🔺 donor s***m for unmarried women

https://plusmedfertility.com/intrauterine-insemination-iui/

10/09/2020

New episode of Frequently asked questions ❔
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Today our reproductologist, obstetrician and gynaecologist Dr. Valeria Skrypynets talks about superovulation stimulation and its types
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Enjoy 💜
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03/09/2020

Principles of male infertility treatment
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Currently, in the treatment of male infertility, the most acceptable are the following statements:
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🔸 all diagnostic and treatment actions for both of married couple should be coordinated, taking into account the woman's reproductive reserve
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🔸 attempts of the treatment should be limited in time
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🔸 eliminate all adverse factors, recommend an adequate rhythm of s*xual life, improve working conditions, recommend proper nutrition. Cancel medications that are not essential and can be harmful to s***m
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🔸 if the basic disease (causative factor) is identified, the treatment should be pathogenic. In cases of idiopathic teratozoos***mia it is recommended to use vitamins, antioxidants, agents that improve microcirculation
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🔸 in case of urethra or additional go**ds inflammation the treatment should be carried out
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🔸 correction of cryptorchidism should be done at the age of 3 years
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🔸 detected varicocele, regardless of its severity, is a subject of surgical treatment
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🔸 during hormone therapy, the length of an uninterrupted course should correspond to 2.5 months, considering the duration of the cycle of s***matogenesis 72-76 day
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🔸 the purpose of androgen therapy of primary (hypergonadotropic) hypogonadism is to maintain a normal male phenotype and enhance s*xual function. The chances of infertility correction in this situation are minimal
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🔸 antiestrogens and gonadotropins of chorionic gonadotropin, recombinant luteinizing hormone (LH) and follicle-stimulating hormone (FSH) have been used relatively successfully for the treatment of infertility due to secondary (hypogonadotropic) hypogonadism. Excessive exposure of prolactin can be blocked by bromocriptinum or dostinex
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🔸 detection of autoimmune infertility requires special treatment
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🔸 in obstructive azoos***mia, attempts of immediate surgical restore of the vas deferens should be limited to uncomplicated situations that allow you to expect a relatively stable result. In other cases, considering the current capabilities of assisted reproductive technologies, attempts should be directed to extract s***m from the epididymis (PESA) or te**is (TESE) followed by IVF-ICSI (in vitro fertilization) by injecting a single s***m into the egg’s cytoplasm
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🔸in case of secretory infertility, a high-tech operation can be performed using the microscope (microTESE) followed by IVF-ICSI as well.
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👨🏻‍⚕️ Oleh Chernichenko - Urologist/andrologist in Medical Center “Plusmed”

Currently, in the treatment of male infertility, the most acceptable are the following statements: 🔸 all diagnostic and treatment actions for both of married couple should be coordinated, taking into account the woman’s reproductive reserve⠀🔸 attempts of the treatment should be limited in ...