Phytoscience Innovation And Consults Ltm

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15/12/2023

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*What causes type 1 diabetes?* Type 1 diabetes occurs when your immune system, the body’s system for fighting infection,...
15/12/2023

*What causes type 1 diabetes?*
Type 1 diabetes occurs when your immune system, the body’s system for fighting infection, attacks and destroys the insulin-producing beta cells of the pancreas. Scientists think type 1 diabetes is caused by genes and environmental factors, such as viruses, that might trigger the disease. Studies such as TrialNet External link are working to pinpoint causes of type 1 diabetes and possible ways to prevent or slow the disease.

*What causes type 2 diabetes?*
Type 2 diabetes—the most common form of diabetes—is caused by several factors, including lifestyle factors and genes.

Overweight, obesity, and physical inactivity
You are more likely to develop type 2 diabetes if you are not physically active and are overweight or have obesity. Extra weight sometimes causes insulin resistance and is common in people with type 2 diabetes. The location of body fat also makes a difference. Extra belly fat is linked to insulin resistance, type 2 diabetes, and heart and blood vessel disease. To see if your weight puts you at risk for type 2 diabetes, check out these Body Mass Index (BMI) charts.

*Insulin resistance*
Type 2 diabetes usually begins with insulin resistance, a condition in which muscle, liver, and fat cells do not use insulin well. As a result, your body needs more insulin to help glucose enter cells. At first, the pancreas makes more insulin to keep up with the added demand. Over time, the pancreas can’t make enough insulin, and blood glucose levels rise.

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23/11/2023
23/11/2023

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23/11/2023

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*What is diabetes?*
Diabetes is a disease that occurs when your blood glucose, also called blood sugar, is too high. Blood glucose is your main source of energy and comes from the food you eat. Insulin, a hormonemade by the pancreas, helps glucose from food get into your cells to be used for energy. Sometimes your body doesn’t make enough—or any—insulin or doesn’t use insulin well. Glucose then stays in your blood and doesn’t reach your cells.

*TYPE 2 DIABETES*
A chronic condition that affect the way the body procceses blood sugar (glucose).
With type 2 diabets, the body either
doesnt produce enough insulin or its resists insulin

*TYPE 1 DIABETES*
A chronic condition in which the pancres produce little or no insulin

In typically appears in adolescence.

*✅STEM CELL THERAPY FOR DIABETES.*

Stem Cell therapy is another most effective treatment for diabetes mellitus because scientists have already proved that _(DoubleStemcell and crystalcells)_ stem cells can be differentiates into pancreatic beta-islet cells. Diabetes is metabolic and autoimmune disease means our body attacks to our own pancreatic cells as foreign cells so the treatment with stem cells _(DoubleStemcell and crystalcell)_ provide immune-regulatory properties and stops the immune attack by secreting anti-inflammatory cytokines (IL-10, TGF-beta and IL-1). Stem cell treatment shows good improvement in diabetes patient because double stem cells,has the capacity to regenerate the beta islets cells.

*TYPE-1 DIABETES:*

stem cell can differentiate or regenerate into pancreatic beta- islet cells & produce more insulin.

♻️ Stem cells therapy also differentiates into new vascularization so it provideds good environment for beta islets regeneration

♻ Stem cell provides immune-regulatory properties by secreting anti-inflammatory cytokines and stop inflammation into the pancreas cells.

*TYPE-2 DIABETES:*

♻ Patient with type-2 diabetes have both insulin resistance and insulin deficiency so stem cell can regenerate into functional beta islets.

♻ After stem cell migration to the injured or dysfunctional area, it repair/regenerate that area so stem cell therapy reduces the resistance property of fat, liver and muscle for insulin.

♻ Stem cell therapy creates immune-regulatory property.

Double Stemcell crystal cell is the best solution to any type of diabetes. And it cures it permanently.

*COMPLICATIONS Of Diabetes:-*

Both type 1 and type 2 diabetes ultimately lead to high blood sugar levels, a condition called “Hyperglycemia”. Over a long period of time, hyperglycemia damages the retina of the eye, the blood vessels of the kidneys, the nerves, and other blood vessels.

*1.Damage to the retina from diabetes* (diabetic retinopathy) is a leading cause of blindness.

*2. Damage to the kidneys* from diabetes (diabetic nephropathy) is a leading cause of kidney failure.

*3. Damage to the nerves* from diabetes (diabetic neuropathy) is a leading cause of foot wounds and ulcers, which frequently lead to foot and leg amputations.

*4. Damage to the nerves* in the autonomic nervous system can lead to paralysis of the stomach, chronic diarrhea, and an inability to control heart rate and blood pressure during postural changes.

*5. Diabetes accelerates atherosclerosis*, (the formation of fatty plaques inside the arteries), which can lead to blockages or a clot (thrombus). Such changes can then lead to heart attack, stroke, and decreased circulation in the arms and legs (peripheral vascular disease).

*6. Diabetes predisposes* people to elevated blood pressure, high levels of cholesterol and triglycerides. These conditions both independently and together with hyperglycemia, increase the risk of heart disease, kidney.

Note:
Currently available treatment .

(medicines, diet, insulin injection and exercise)
can control blood sugar but cannot cure diabetes. Over the past several years, doctors have attempted to cure diabetes via transplanting functional insulin producing beta-islet cells and pancreas from donor.

However, the requirement for steroid immunosuppressant therapy to prevent rejection of the pancreatic cells, increases the metabolic demand on insulin-producing cells and eventually they may exhaust their capacity to produce insulin and also shown deleterious effect on pancreas cell and shown less successful result.
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