Neural Stem Cell Institute

09/04/2025

Available now at Stem Cell Reports: Our study led by Farhad Farjood, Nathan Boles and Jeffrey Stern reveals the surprising heterogeneity of retinal pigment epithelium (RPE) cells in the human eye using single cell transcriptomics and proteomics. Using the cell surface proteins identified with BioLegend's CITE-seq panel, we describe unique spatial patterns that suggest functional differences for RPE subpopulations in the eye.

- with Swapna Nandakumar, Taylor Bertucci, Thomas Kiehl, Steven Lotz, Yue (Jenny) Wang, Jacob Black, Skanda Sai, Jade Kozak, Brigitte Arduini and Sally Temple

This work was supported by the National Eye Institute and Luxa Biotechnology LLC.

Full text | https://zurl.co/4hwI6
International Society for Stem Cell Research

Cell Press

Farjood et al. has set the stage for characterizing RPE heterogeneity by using single-cell sequencing technology to identify cell surface markers compatible with isolating each subpopulation for further study. Using these markers, select RPE subpopulations are shown to have unique localization withi...

08/11/2025

🔊 Are you a detail-oriented PhD scientist with cell biology or experience? Interested in development of a novel clinical stage cell replacement therapy for dry age-related (AMD)? We are !

Learn more: https://zurl.co/uwrDd

07/29/2025

Today, Liz Fisher presents "PLD3 contributions to vascular dysfunction in the context of AD" during the poster session at !

Poster | #107171
Time | 7:30AM – 4:15PM
Where | Exhibit Hall

07/27/2025

Today at : Taylor Bertucci presents "APOE4 alters vascular cells in cognitively normal brains and in vitro models revealing early pathogenic AD contributions of endothelial cells."

Session | Dissecting molecular disease mechanisms
Time | 2:00 – 3:30PM
Location | Hall G

07/21/2025

Coming up at , Taylor Bertucci and Liz Fisher will present data related to APOE and PLD3 contributions to vascular dysfunction in Disease. Check it out!

Alzheimer's Association | https://zurl.co/jgQ7m

The Alzheimer's Association International Conference is the world's largest forum for the dementia research community. Toronto, Canada, and online.

06/13/2025

🔊 Just announced! Susan Sharfstein of SUNY Polytechnic Institute
led a successful grant application to develop next generation devices enabling advanced real-time measurement and manipulation in cellular systems. Our own Tom Kiehl, Taylor Bertucci and Brigitte Arduini will collaborate with this interdisciplinary team from University at Albany, SUNY, AIM Photonics, Binghamton University, Hudson Valley Community College, and Bronx Community College.

06/03/2025

We had a terrific time with the students hosted by Albany College of Pharmacy and Health Sciences and the CBET program! These students are the future of pharmacy, biomanufacturing, bioengineering, and cell science. We love to see it!

Many thanks to Brigitte Arduini, Liz Fisher, Runia Roy, Jade Kozak, Carmen Nazario, Dylan Murphy, Susan Goderie, Habiba Khan, Sally Temple and Jeffrey Stern!

06/02/2025

Proceedings from the 2024 Global Tau Conference are available through the Alzheimer's Association in collaboration with Curepsp and the .

Full text | https://zurl.co/0AnwI

Recent years have seen major advances in tau-associated brain disorders through interdisciplinary research spanning molecular biology, neuroimaging, clinical trials, and therapeutic development. The...

05/29/2025

Paul D. Tonko we're so glad we had an opportunity to discuss our work with you today! We deeply appreciate your advocacy in support of our shared goal - to improve healthcare options for patients and ultimately develop cures for Alzheimer's Disease, Macular Degeneration and other neurodegenerative conditions.

05/22/2025

We were thrilled to host Dr. Kristen Brennand of Yale University this week! She gave a terrific talk on "Using Stem Cells to Explore the Genetics Underlying Brain Disease."

05/17/2025

Congrats to the winners and to everyone who completed the CDPHP !

Times Union coverage | https://zurl.co/DDAjZ

Jared Lamson and Karen Bertasso-Hughes claimed top honors at the 2025 CDPHP Workforce Team Challenge in Albany, finishing first in the 3.5-mile race.

05/16/2025

We had a blast at the CDPHP ! Jack Huber took 2nd place overall for the 2nd year in a row and the whole team enjoyed the event.