07/19/2025
Let’s talk about something that should never have become controversial: low-dose vaginal estrogen.
For decades, we’ve had solid evidence showing it’s one of the safest and most effective tools we have for treating genitourinary symptoms of menopause—like dryness, painful s*x, and recurrent UTIs. But thanks to an outdated black box warning, many doctors hesitate to prescribe it, and countless women suffer unnecessarily.
At Thursdays FDA hearing, Dr. Rachel Rubin delivered a bold, evidence-backed message: this warning is doing more harm than good.
Every year, millions of women end up in the ER for preventable UTIs. We're talking billions in avoidable healthcare costs—and even more importantly, years of avoidable pain, fear, and frustration.
It’s time to drop the fearmongering and let the data lead. Removing this label could drastically reduce infections, protect long-term health, and give women back control over their bodies.
The science is on our side. The question is—will the FDA finally listen?