ClearFlow, Inc.

04/24/2026

Avoid retained blood around the heart, reduce the risk of POAF.

Clear chest tubes proactively with the PleuraFlow® Active Clearance Technology® (ACT) System.

Check it out at https://clearflow.com/

04/22/2026

Improve clinical conditions of cardiac patients, reduce post-surgery complications.
Active chest tube clearance (ATC) more effective than conventional chest tube (CT), a recent meta-analysis.

After heart surgery, the chest tube removes lost mediastinal blood. Clogging of the chest tube may induce inadequate evacuation of fluids surrounding the lungs and heart, leading to deadly consequences. This meta-analysis compared the effectiveness of active chest tube clearance (ATC) with conventional chest tube (CT) in lowering the incidence of retained blood complications after heart surgery. We conducted a systematic search of the available databases to identify cohort studies or clinical trials that met our inclusion criteria. Studies that compared active tube clearance and conventional tube in cardiac surgery were included. The fixed or random-effects model was used to determine the pooled effect estimates upon the heterogeneity of collected data. This review included 7003 people from five cohort studies and three clinical trials. This meta-analysis provides evidence on the positive effect of active maintenance of chest tube patency during the first hours of cardiac surgery, which resulted in reducing the incidence of complications.

More on this systematic review and meta-analysis can be found here: https://doi.org/10.1007/s42399-022-01257-3

AUTHORS & AFFILIATIONS:
Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt
Mohammed Tarek Hasan, Abdulrahman Ibrahim Hagrass, Mohamed Nabil Elkhrashy, Mohamed Hamouda, Anas Zakarya Nourelden & Ahmed Bostamy Elsnhory
International Medical Research Association (IMedRA), Cairo, Egypt
Mohammed Tarek Hasan, Abdulrahman Ibrahim Hagrass, Mohamed Nabil Elkhrashy, Mohamed Hamouda, Noura Mohamed shada, Sarah M. Hashem, Mohammed Al-kafarna, Hossam Waleed Almadhoon, Khaled Mohamed Ragab, Anas Zakarya Nourelden & Ahmed Bostamy Elsnhory
Gamal Abdel Nasser Axis, The 3rd Settlement, New Cairo, Egypt
Abdulrahman Ibrahim Hagrass
Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
Noura Mohamed shada & Sarah M. Hashem
Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine
Mohammed Al-kafarna
Faculty of Dentistry, Al-Azhar University, Gaza, Palestine
Hossam Waleed Almadhoon
Faculty of Medicine, Minia University, Minia, Egypt
Khaled Mohamed Ragab

CONTRIBUTIONS:
Conception and design of the work by Khaled Mohamed Ragab and Ahmed Bostamy Elsnhory.
Selection process and data collection by Mohammed Tarek Hasan, Mohamed Nabil Elkhrashy, Mohamed Hamouda, Noura Mohamed shada, and Sarah M. Hashem.
Data analysis and interpretation by Abdulrahman Ibrahim Hagrass and Khaled Mohamed Ragab.
Drafting the article by Mohammed Al-kafarna and Hossam Waleed Madhoon.
Critical revision and editing of the article by Abdulrahman Ibrahim Hagrass, Ahmed Bostamy Elsnhory, and Anas Zakarya Nourelden.
CORRESPONDING AUTHOR:
Correspondence to Abdulrahman Ibrahim Hagrass.

After heart surgery, the chest tube removes lost mediastinal blood. Clogging of the chest tube may induce inadequate evacuation of fluids surrounding the lungs and heart, leading to deadly consequences. This meta-analysis compared the effectiveness of active chest tube clearance (ATC) with conventio...

04/16/2026

Get support for common challenges of the PleuraFlow® Active Clearance Technology® (ACT) System in the ICU and operating room.

Use the new ClearFlow Assistant app any time, right from your mobile device. Check it out: https://clearflow.com/clinical-support/

04/14/2026

Surgeons see serious adverse complications associated with clogged chest tubes, a common cause for hospital readmission. What steps can be taken to reduce these readmissions? https://t.co/9UY83Ed93X

https://www.clearflow.com/chest-tube-clogging-is.../

Chest Tube Clogging is Associated with Significantly Higher Rates of A-Fib and Other Hospital Complications Chest tubes clog after cardiac surgery. This is a known fact that has been acknowledged by 100% of surgeons surveyed, most of whom also report seeing serious adverse complications associated w...

04/10/2026

Reduce hospital stay.

Provide patients with a rapid return to pre-surgery activities related to sternal closure following cardiothoracic surgery. Take a look at the ClearFix Rigid Sternal Fixation system and get started.

For the science behind plate fixation read: Orthopedic Principles to Facilitate Enhanced Recovery After Cardiac Surgery created by Marc Gerdisch, MD, FACS, FACC, FHRS, MD, Keith Allen, Yoshifumi Naka, MD, PhD, Mark Bonnell, MD, Kevin Landolfo, MD, John Grehan, MD, PhD, Kendra J. Grubb, MD, MHA, FACC, MD, David J. Cohen, MD, T. Sloane Guy, MD, Nirav C. Patel, MD, Vinod Thourani, MD.

For a demo of the ClearFix Rigid Sternal Fixation system,
reach out to Tony Mathiason here on Linkedin.

Check it out at https://lnkd.in/gtt28_jV

04/08/2026

Minimize Retained Blood Syndrome (RBS) and reduce

• Reinterventions.
• In-hospital mortality.
• Intensive care unit and hospital stays.
• Incidence of renal replacement therapy.

Don't let RBS block your patient's recovery. Check out your options at https://www.clearflow.com/

04/06/2026

The standard, often overlooked, practice by Dr. Gillinov, Chief of Cardiac Surgery at the Cleveland Clinic.

Marc Gillinov, MD, Chairman of the Department of Thoracic and Cardiovascular Surgery at the Cleveland Clinic, shared the importance and benefit of avoiding chest drain occlusion to prevent the inflammatory consequences of retained blood after cardiac surgery. Watch the entire webinar from the Arab Health Conference filmed in January 2022. https://lnkd.in/dNgPU_Vj

You can avoid chest drain occlusion and prevent complications and hospital costs with the PleuraFlow system that Dr. Gillinov mentions. Find documentation here: https://clearflow.com/

03/26/2026

Improve cost and quality care for cardiac surgery patients.
PleuraFlow®ACT®System — a catheter system developed by cardiothoracic surgeons for better outcomes.

Get started here: https://clearflow.com/

03/24/2026

Surgery efficiencies, reduced costs, and overall better outcomes for your patients.

When you follow the evidence-based ERAS Cardiac Surgery Society around the use of Rigid Sternal Fixation systems, you improve your patients postoperative recovery, reduce complications, and save on your budget.

For the science behind plate fixation read: Orthopedic Principles to Facilitate Enhanced Recovery After Cardiac Surgery created by Marc Gerdisch, MD, FACS, FACC, FHRS, MD, Keith Allen, Yoshifumi Naka, MD, PhD, Mark Bonnell, MD, Kevin Landolfo, MD, John Grehan, MD, PhD, Kendra J. Grubb, MD, MHA, FACC, MD, David J. Cohen, MD, T. Sloane Guy, MD, Nirav C. Patel, MD, Vinod Thourani, MD.

For a demo of the ClearFix Rigid Sternal Fixation system,
reach out to Tony Mathiason here on Linkedin.

Check it out at https://lnkd.in/gMgY3_NU

03/19/2026

Reduce readmissions, a strategy.

Approximately 20% of readmissions are caused by pleural or pericardial effusions.

The "Leave no clot behind" strategy appears to reduce the complications from effusions and impact outcomes.

Large volume clots must be surgically evacuated in a re-exploration procedure in the early days after surgery. Smaller, more focal clots that compress the heart can lead to hemodynamic compromise (pericardial tamponade) that can threaten the patient's life. These can require a subsequent drainage pr...

03/17/2026

Surgery cost savings that improve outcomes for all hospital patients.

When you use the ClearFix Rigid Sternal Fixation system at your facility, you improve postoperative recovery, reduce complications, and save on budgets that can be redirected to improve facilities and equipment which contribute to better patient outcomes and quality of care.

For the science behind plate fixation read: Randomized, multicenter trial comparing sternotomy closure with rigid plate fixation to wire cerclage created by Keith Allen, Vinod Thourani, MD, Yoshifumi Naka, MD, PhD, Kendra J. Grubb, MD, MHA, FACC, MD, Grehan, MD, PhD, Nirav Patel, MD, T. Sloane Guy MD, Kevin Landolfo, MD, Marc Gerdisch, MD, FACS, FACC, FHRS, MD, Mark Bonnell, MD, and David J. Cohen, MD.

For a demo of the ClearFix Rigid Sternal Fixation system,
reach out to Tony Mathiason here on Linkedin.

Check it out at https://lnkd.in/gtt28_jV

03/06/2026

Surgery efficiencies, reduced costs, and overall better outcomes for your patients.

When you follow the evidence-based ERAS Cardiac Surgery Society around the use of Rigid Sternal Fixation systems, you improve your patients postoperative recovery, reduce complications, and save on your budget.

For the science behind plate fixation read: Randomized, multicenter trial comparing sternotomy closure with rigid plate fixation to wire cerclage created by Keith Allen, Vinod Thourani, MD, Yoshifumi Naka, MD, PhD, Kendra J. Grubb, MD, MHA, FACC, MD, John Grehan, MD, PhD, Nirav Patel, MD, T. Sloane Guy, MD, Kevin Landolfo, MD, Marc Gerdisch, MD, FACS, FACC, FHRS, MD, Mark Bonnell, MD, and David J. Cohen, MD.

For a demo of the ClearFix Rigid Sternal Fixation system,
reach out to Tony Mathiason here on Linkedin.

Check it out at https://lnkd.in/gMgY3_NU