Hogan Lab at Michigan Medicine University of Michigan

07/23/2025

Dr Hogan and Lukacs recently published a review article in Nature Review Immunology discussing how different routes of exposure to food antigens can contribute to allergic sensitization and describe how mast cells ultimately drive the allergic reaction to these food allergens.

https://pubmed.ncbi.nlm.nih.gov/40571771/

05/14/2025

Congratulations to Jazib Uddin, the Hogan Lab and our collaborators, O’Roirdan, Lukacs, Denson, Haberman, O’Dwyer, Divanovic, Weaver, Nusrat and Parkos Labs on the publication of the article in JCI Insight describing a role for STARD7 in intestinal epithelial mitochondrial function and barrier integrity and susceptibility to IBD.

Outstanding team effort between Cincinnati Children’s Hospital and Michigan Medicine!

3Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

04/22/2025

Congratulations to Hogan Lab's very own Dr Hock Tay for winning the M-FARA Symposium's poster contest this year! Dr Baker (pictured with Hock) presented him with the award for his poster entitled "T-Cell Heterogeneity in the Intestinal Mucosa: Transcriptional Programs Driving IL-9 and IL-13 Production and T-Cell Pathogenicity in Food Allergy."

03/05/2025

It was great catching up and reminiscing with old friends and mentors at this year's AAAAI Conference.
Pic 1: Ariel Munitz PhD, Mark Rothenberg MD PhD, Simon Hogan PhD, Yushi Wang
Pic 2: Luqman Seidu MD, Miguel Stein MD, Ariel Munitz PhD, Simon Hogan PhD, Jennifer Bullock MD

Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's
Ariel Munitz

01/31/2025

The MHWFAC Annual Report is out and there are so many exciting things that came out of 2024. Make sure to check out page 16 for a highlight of the work Dr Hogan and Dr Susie Min have been focusing on regarding allergic disorders of the esophagus.

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12/23/2024

Hogan Lab wishes everyone a Happy holiday season!
We wish everyone a joyful and prosperous 2025!

12/17/2024

Great having Hogan lab Alumni Sunil Tomar PhD visiting from San Diego!

Sunil is doing awesome work in San Diego with Poseida Therapeutics!

During his visit, Sunil was kind enough to talk with trainee's about his experiences in the Lab and journey in Biotechnology and Industry!

Keep up the great work Sunil!

11/04/2024

https://www.facebook.com/photo/?fbid=1046841480566573&set=a.204183541499042

As we celebrate our 75th anniversary, we're reconnecting with distinguished alumni to reflect on their experiences and the impact JCSMR has had on their careers. Today, we feature Professor Simon Hogan (Hogan Lab at Michigan Medicine University of Michigan), Askwith Research Professor of Food Allergy and Professor of Pathology at the University of Michigan, Ann Arbor, USA.

Read: https://jcsmr.anu.edu.au/news-events/news/finding-community-jcsmr-journey-self-doubt-scientific-excellence

Science at The Australian National University

09/27/2024

Kudos to Christian Rizza for his seminar talk last week at the Pathology Research Seminar Series! Christian presented an enthralling talk on "Utilizing Human Inducible Pluripotent Stem Cells to Study Mast Cells". Way to go, Christian!

08/14/2024

Congratulations to Gila Idelman and Christian Rizza on acceptance of their manuscript in the journal Mucosal Immunology!

This joint effort by the Hogan, Schuler and Baker labs within the Mary H. Weiser Food Allergy Center describes the usage of a human inducible pluripotent stem cell system to study developmental trajectories of mast cells.

Mast cells (MCs) are derived from CD34+ hematopoietic progenitors, consist of different subtypes and are involved in several inflammatory conditions. However, our understanding of human MC developmental trajectories and subtypes have been limited by a scarcity of suitable cellular model s...

07/09/2024

Lab member Dr James Krempski’s study on transcriptional programs involved in vascular endothelial dysfunction in severe IgE mediated reactions has been accepted for publication in the Journal of Allergy and Clinical Immunology.
Congratulations to James and the Hogan Lab members and our collaborators in the Shaomeng Wang Lab and Obi Lab at Michigan Medicine on this great achievement! Click the link to read our article, "IL-4-STAT6 axis amplifies histamine-induced vascular endothelial dysfunction and hypovolemic shock."
University of Michigan Department of Pathology
Michigan Medicine

https://pubmed.ncbi.nlm.nih.gov/38777155/

06/11/2024

The Hogan Lab would like to welcome Paula Reichel to the team as a PhD candidate!
Paula is finishing her rotation project focused on the role of STARD7 in IBD. In addition, she is planning her PhD project which will investigate the connection between food antigen uptake in the GI tract by antigen passages and the escalation from sensitization to food allergy.