14/07/2025
I recommended Creatine as a supplement for Thyroid Dysfunction. Client antidotes include feeling better than ever before with energy skyrocketing, but here is the science of it.
Creatine positively impacts the innate immune system.
This is another big one for thyroid patients, specifically those with Hashimoto’s thyroiditis.
Creatine has been shown to act on the immune system and is considered to have immunomodulatory potential (8).
effects of creatine on the immune system
More specifically, it has been shown to down-regulated something called toll-like receptors.
These are the same receptors that, when dysfunctional, lead to autoimmune diseases like Hashimoto’s and Graves’.
This means creatine may have the potential to be used as a treatment for balancing the immune system in those with these autoimmune thyroid conditions!
And when you look at the numbers, both Hashimoto’s and Graves’ disease account for the majority of cases of both hypothyroidism and hyperthyroidism making this a very interesting treatment.
As you probably are all aware if you have one of these conditions, there are very few actual treatments that target the immune component of these diseases.
Most of the treatments focus primarily on the thyroid function aspect while ignoring the more important immune component.
We may be able to add creatine to the list of thyroid-altering treatments along with CBD, LDN, vitamin D3, black seed oil, pycnogenol, and more.
On top of this benefit of toll-liked receptors, creatine has also been shown to alter the release of inflammatory cytokines by influencing the NFkb pathway.
For perspective, this is the same pathway that turmeric (curcumin) acts on to reduce inflammation and curcumin has over 1,000 studies showing its efficacy as well.