Dr. Jason Winkelmann

03/12/2026

Part 3: Migraines are really complex. But that doesn't mean treatments automatically need to be. Starting with, and mastering, the basics is essential. It may not completely end your migraines but it will make all other treatments more effective. So what do you have to lose?

03/11/2026

Part 2: Migraines are really complex. But that doesn't mean treatments automatically need to be. Starting with, and mastering, the basics is essential. It may not completely end your migraines but it will make all other treatments more effective. So what do you have to lose?

03/09/2026

Part 1: Migraines are really complex. But that doesn't mean treatments automatically need to be. Starting with, and mastering, the basics is essential. It may not completely end your migraines but it will make all other treatments more effective. So what do you have to lose?

03/08/2026

https://www.mytruehealthcenters.com/post/magnesium-for-chronic-pain

Can magnesium help chronic pain? Learn how magnesium affects nerve signaling, muscle tension, mitochondria, and central sensitization—and why it may support pain regulation, but isn’t a standalone solution.

03/07/2026

Putting it all together: why you should be consuming more magnesium for your chronic pain, and what to take for best results.

You shouldn't try a new therapy unless you understand why you are doing it. You've heard all the wonderful things about magnesium, but how does it help chron...

03/06/2026

Part 5: Not all magnesium supplements are created equal.
Magnesium is an unstable ion, it must be bound to something to be absorbed.
For chronic pain, the goal is absorption and bioavailability.

The most effective forms for systemic magnesium replenishment:
• Magnesium glycinate
• Magnesium citrate
The one to avoid for pain support:
• Magnesium oxide (poor absorption, primarily a diuretic)

If you’ve tried magnesium and it “didn’t work,” the issue is often:
• The wrong form
• Insufficient dosing
• No loading phase

In this video, I explain:
• How to think about magnesium dosing
• Why RDA levels are often too low for chronic pain
• How to identify your working dose

Magnesium isn’t a cure-all—but it is foundational physiology.

03/05/2026

Part 4: One of the most powerful pain receptors in your nervous system is the NMDA receptor.
When activated, it amplifies pain signals and contributes to central sensitization, the process where the nervous system becomes overly responsive.
Magnesium naturally regulates this receptor.
It:
• Helps control excess glutamate
• Blocks excessive calcium influx
• Reduces abnormal pain signaling
In fact, magnesium binds to this receptor at a significant percentage of the strength of ketamine—one reason it has been studied in CRPS and post-surgical pain reduction.
If you feel like your nervous system is “stuck on high,” this mechanism is critical.
In this video, I break down:
• How NMDA receptors amplify pain
• Why centralized pain persists even after tissue healing
• Why magnesium may reduce morphine requirements post-surgery

03/04/2026

Part 3: Did you know magnesium is required to convert plant-based omega-3s into their active anti-inflammatory forms?
Most people know EPA and DHA reduce inflammation. But if you rely on plant sources (ALA), your body must convert them, and that pathway requires magnesium-dependent enzymes.
Without adequate magnesium, this already inefficient process becomes even weaker.
For patients with chronic inflammation, autoimmune pain, or centralized sensitivity, this matters.
In this video, I explain:
• Why ALA must convert to EPA and DHA
• The magnesium-dependent enzymes in that pathway
• Why inflammation persists even when you “eat clean”
Magnesium doesn’t just relax muscles—it influences inflammatory chemistry at the enzymatic level.

03/03/2026

Part 2: If you have chronic pain and fatigue, magnesium may be affecting something deeper than muscle tension. It may be affecting your cellular energy.
ATP is your body’s energy molecule. But ATP is unstable on its own. Magnesium binds to ATP, stabilizing it so it can be transported to tissues that need repair.
No magnesium = inefficient energy delivery.
And when energy production is compromised, tissue repair slows. Pain lingers. Recovery stalls.
If you’ve tried magnesium but “didn’t feel more energy,” it may not be about energy in the way you think. It may be about tissue healing and mitochondrial stability.
In this video, I explain:
• Why magnesium is required for ATP stability
• The connection between fatigue and chronic pain
• Why bioavailability matters more than brand names

03/02/2026

Part 1: If you live with chronic pain and constantly tight, achy muscles, magnesium may be one of the most overlooked pieces of the puzzle.
Magnesium is not just “a supplement for cramps.” It directly regulates muscle contraction at the cellular level. When calcium binds inside your muscle fibers, the muscle contracts. Magnesium is what displaces calcium so the muscle can relax.
If you feel like your body is always braced, guarded, or stuck in tension—even when imaging is normal—this mechanism matters.
But here’s the key: form and dosing determine whether magnesium actually works.
In this video, I break down:
• Why magnesium is nature’s muscle relaxer
• How calcium-magnesium balance affects chronic pain
• Why many people say “magnesium didn’t work for me”

03/01/2026

https://www.mytruehealthcenters.com/post/fat-and-chronic-pain

Discover why dietary fat is misunderstood and how it affects inflammation, mitochondrial energy, and nerve sensitivity in chronic pain.

02/28/2026

Putting it all together. Fat is an essential nutrient for healing all chronic pain conditions. But the wrong kind can make things much worse.

Dietary fat has been misunderstood for decades, yet it plays a critical role in chronic pain recovery. In this video, I explain why healthy fats are essentia...