BioSurfaces LLC

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BioSurfaces LLC

BioSurfaces is a leader in producing medical devices using our proprietary electrospinning process (Bio-Spun).

Our Bio-Spun materials induce tissue integration, reduce foreign body reaction, are structurally versatile and can locally deliver drug(s). BioSurfaces, LLC seeks to improve the quality of medical care by augmenting existing and emerging medical approaches with our cutting-edge nanotechnology. The use of yesterday’s technology in today’s medical devices causes unacceptable complication rates and fatalities. The direct implementation of our nanotechnology allows us to deliver innovative solutions that show significant improvements over industry standards. We believe that our solutions are the future of biomedical devices, and will dramatically improve patients’ quality of care upon their use.

01/27/2026

Week 1 – Optimist vs. Realist – The Struggle Is Real

What happens when a lifelong scientific optimist runs head-first into the realities of biotech entrepreneurship?

In this week’s blog, Matt shares an honest look at fundraising, stalled deals, broken partnerships, and why optimism fuels discovery—but doesn’t always translate cleanly to business. He also highlights why IVRT and Bio-Spun™ scaffolds give us confidence as momentum builds toward more human-relevant, non-animal testing models.

If you’ve ever balanced hope with hard-earned realism, this one will resonate.

👉 Read the full post: https://www.biosurfaces.us/single-post/week-1-optimist-vs-realist-the-struggle-is-real

01/16/2026

We’ve been laying the groundwork for what’s next — and we’re excited to start sharing it.

Over the coming weeks/months, we’ll be releasing a new publication based on our In Vitro Research Tools (IVRT) and the benefits of our material for tissue model development, alongside a new and improved Spin Cycle page that dives into new data and updated insights. We’re also putting the finishing touches on an IVRT animation, scheduled to drop next month, that brings the work to life in a new way.

There’s a lot ahead, and this is just the beginning. Stay tuned for what’s coming next.

01/09/2026

The U.S. Senate has unanimously passed the FDA Modernization Act 3.0, directing FDA to update drug regulations to reflect modern nonclinical testing approaches, including in vitro and other human-relevant methods.

As regulators continue to embrace New Approach Methodologies (NAMs), platforms like BioSurfaces’ IVRT (In Vitro Research Tools) are increasingly important. BioSurfaces’ IVRT platform supports nonclinical research by enabling reproducible, human-relevant in vitro data generation—aligned with FDA’s push to modernize drug development and reduce reliance on animal testing.

This legislation reinforces a clear direction: future-ready science will be human-relevant, data-driven, and in vitro–enabled.

Learn more about BioSurfaces’ IVRT products: https://www.biosurfaces.us/ivrt

12/19/2025

✨ Week 11 – Reflecting on a Busy Year at BioSurfaces ✨

As we close in on the end of the year, Matt shares an inside look at how far our small-but-mighty team has come — from strengthening our investor messaging to seeing global growth in our Bio-Spun™ IVRT product line.

2024 began with uncertainty, but 2025 has far exceeded expectations. We’ve:
🔹 Expanded our customer base and global distribution
🔹 Seen strong validation of our Bio-Spun™ scaffolds across new tissue models
🔹 Continued to innovate in cell therapy, medical devices, and internal technologies
🔹 Restarted key programs including our NuSpun™ Vascular Graft and Bio-Spun™ Fistula Plug

There’s nothing better than seeing years of hard work start turning into real traction — and we're heading into 2026 with momentum and optimism.

Matt also reflects personally on the challenges, the wins, and the support of our readers who follow our journey each week.

Read the full Week 11 blog here: https://www.biosurfaces.us/single-post/week-11-reflecting-on-a-busy-year

And from all of us at BioSurfaces — wishing you a warm, healthy, and happy holiday season!

12/01/2025

🎉 BioSurfaces End-of-Year Sale Is Live! 🎉

As 2025 approaches, we’re offering exclusive year-end discounts on our Bio-Spun™ In Vitro Research Tools. Whether you’re scaling up studies or planning for next year’s experiments, now is the perfect time to save.

💥 Special Pricing Available Through December 31st
🧪 Bio-Spun™ Plates
🧫 Bio-Spun™ Inserts
🧵 Custom Electrospun Scaffolds
👉 Shop the sale here: https://www.biosurfaces.us/ivrtstore

11/28/2025

Why Are We Still Growing Human Cells on Flat Plastic?

This week’s blog dives into a critical issue: most benchtop tools used today don’t reflect how cells behave in the human body. It’s a big reason why 93% of drugs fail once they reach clinical trials, costing billions and delaying real treatments.

BioSurfaces’ Bio-Spun™ IVRT technology is gaining major traction — new distributors, global agreements, co-marketing deals, and external researchers showing beautiful 3D tissue growth on our scaffold. After 22 years derisking this platform, we’re hitting a major turning point and continuing our Series A raise to scale what’s next.

If you care about reducing animal testing, improving drug success rates, or creating more human-relevant models, this is a must-read.

👉 Check out the full blog: https://lnkd.in/eAsXX-BD

11/21/2025

Six years ago today, our website had visitors from 43 countries. Today, we’re proud to share that this number has grown to 129 countries. 🌍

The graphic below truly shows how far we’ve come — and just how global the interest in our technology has become. (The shaded blue regions represent where users are visiting from; darker blue indicates higher activity.)

As we move into 2026, our focus shifts to the next phase: turning this worldwide engagement into meaningful customer partnerships.

Stay tuned — we’ll soon be announcing special end-of-year pricing on our In Vitro Research Tools (IVRT) product line. Big things ahead!

11/07/2025

During a recent trip to Arizona, Matt and Tina met an unlikely teacher—a pigeon they named “Broken Wing.” 🕊️

What started as a simple lunch break turned into a reflection on facing challenges, taking risks, and believing in the journey—even when the odds aren’t perfect.

Check out this week’s blog to see how Broken Wing’s story connects to BioSurfaces’ own path forward.

➡️ Read here: https://www.biosurfaces.us/single-post/week-9-broken-wing

10/20/2025

🌟 Advancing Cell Therapy, One Chamber at a Time 🌟

Our Bio-Spun™ Cell Chamber is redefining how long-term cell-based therapies are delivered — combining biomaterials innovation with practical design for real-world treatment challenges.

Built to support sustained therapeutic delivery, enhanced cell viability, and seamless integration with research and clinical applications — Bio-Spun™ technology is helping turn what once seemed impossible into reality.

🎥 Watch the video to see how we’re shaping the future of regenerative medicine.

For more information about our product offerings click here:
https://lnkd.in/d5hjN2Hv

10/10/2025

🍂 Week 8 – Let’s Shock the World!

Fall is here — and while the leaves are changing, so is the world of biomaterials. In the latest blog, Matt reflects on the balance between business growth and innovation, the importance of working with true do-ers, and why it’s time for the medical device industry to take bold steps forward.

From presenting at the BioInterface meeting to seeing electrospinning rise as a mainstay technology, Matt shares why now is the moment to challenge the status quo and shock the world with innovation.

💥 Read the full blog here: https://lnkd.in/ejx3VWQN

10/02/2025

🚀 Big news from BioSurfaces!

Our CEO, Matt, had the opportunity to present at the SIBF (Society for Biomaterials Foundation) event, sharing how BioSurfaces is leveraging our Bio-Spun™ technology to transform both in vitro research tools and therapeutic applications.

It was an incredible platform to highlight not only our growth and innovation, but also the potential impact of nanofiber-based scaffolds in advancing science and healthcare.

👏 Huge thanks to SIBF for the invitation and to everyone who engaged in thoughtful discussions about where this technology is heading!

10/01/2025

We’re proud to share that Rayan Hodroj presented her poster at SIBF:

Bio-Spun™ Cell Chamber: An Innovative Electrospun Composite Cell Chamber Designed to Promote Tissue Integration, Minimize Fibrosis, Provide Immunoprotection and Deliver a Targeted Therapeutic

This work highlights the potential of the Bio-Spun™ Cell Chamber to address key challenges in cell-based therapies.

You can view the full poster here 👉https://www.biosurfaces.us/_files/ugd/b56c33_2ec80409d0694e1e9f49f65c3732a871.pdf

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200 Homer Avenue
Ashland, MA
01721

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http://www.biosurfaces.us/

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